cis-acting RNA elements required for replication of bovine viral diarrhea virus–hepatitis C virus 5′ nontranslated region chimeras

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

1988 • 1,325 citations

Internal ribosome entry site within hepatitis C virus RNA

1992 • 914 citations

Transmission of Hepatitis C by Intrahepatic Inoculation with Transcribed RNA

1997 • 718 citations

Molecular Characterization of Pestiviruses

1996 • 506 citations

The mechanism of RNA recombination in poliovirus

1986 • 503 citations

Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants

1987 • 476 citations

Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA

1996 • 450 citations

Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism

1993 • 435 citations

Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein.

1990 • 428 citations

Sequence analysis of the 5' noncoding region of hepatitis C virus.

1992 • 410 citations

Secondary structure of the 5′ nontranslated regions of hepatitis C virus and pestivirus genomic RNAs

1992 • 402 citations

Unique features of internal initiation of hepatitis C virus RNA translation.

1995 • 340 citations

Dengue type 4 virus mutants containing deletions in the 3' noncoding region of the RNA genome: analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys

1996 • 322 citations

Structure of the 3' terminus of the hepatitis C virus genome

1996 • 286 citations

Transcription of infectious yellow fever RNA from full-length cDNA templates produced by in vitro ligation.

1989 • 281 citations

Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA.

1996 • 255 citations

Structural Requirements for Initiation of Translation by Internal Ribosome Entry within Genome-Length Hepatitis C Virus RNA

1996 • 253 citations

Sequence and structural elements that contribute to efficient encephalomyocarditis virus RNA translation

1992 • 229 citations

An RNA pseudoknot is an essential structural element of the internal ribosome entry site located within the hepatitis C virus 5' noncoding region.

1995 • 220 citations

Genetic Analysis of Internal Ribosomal Entry Site on Hepatitis C Virus RNA: Implication for Involvement of the Highly Ordered Structure and Cell Type-Specific Transacting Factors

1997 • 209 citations

Spontaneous and Engineered Deletions in the 3′ Noncoding Region of Tick-Borne Encephalitis Virus: Construction of Highly Attenuated Mutants of a Flavivirus

1998 • 208 citations

Nucleotide sequence of classical swine fever virus strain Alfort/187 and transcription of infectious RNA from stably cloned full-length cDNA

1996 • 203 citations

Pestivirus translation initiation occurs by internal ribosome entry

1995 • 189 citations

Ligation-anchored PCR: a simple amplification technique with single-sided specificity.

1992 • 181 citations

Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus.

1996 • 162 citations

Attenuation of Mengo virus through genetic engineering of the 5′ noncoding poly(C) tract

1990 • 161 citations

Almost the entire 5′ non‐translated region of hepatitis C virus is required for cap‐independent translation

1995 • 159 citations

Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication

1997 • 150 citations

Infectious Bovine Viral Diarrhea Virus (Strain NADL) RNA from Stable cDNA Clones: a Cellular Insert Determines NS3 Production and Viral Cytopathogenicity

1998 • 149 citations

Internal entry of ribosomes is directed by the 5' noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon

1997 • 147 citations

5′ and 3′ untranslated regions of pestivirus genome: primary and secondary structure analyses

1993 • 144 citations

A conserved helical element is essential for internal initiation of translation of hepatitis C virus RNA

1994 • 141 citations

Growth-Restricted Dengue Virus Mutants Containing Deletions in the 5′ Noncoding Region of the RNA Genome

1995 • 136 citations

Combinatorial Screening and Rational Optimization for Hybridization to Folded Hepatitis C Virus RNA of Oligonucleotides with Biological Antisense Activity

1997 • 131 citations

Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes

1996 • 122 citations

Serine protease of pestiviruses: determination of cleavage sites

1997 • 110 citations

Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes

1996 • 100 citations

Complete Genomic Sequence of Border Disease Virus, a Pestivirus from Sheep

1998 • 97 citations

Encephalomyocarditis viruses with short poly(C) tracts are more virulent than their mengovirus counterparts

1995 • 75 citations

The Influence of AUG Codons in the Hepatitis C Virus 5′ Nontranslated Region on Translation and Mapping of the Translation Initiation Window

1996 • 69 citations

A common structural core in the internal ribosome entry sites of picornavirus, hepatitis C virus, and pestivirus

1996 • 59 citations

Replication of the genomic RNA of a positive-strand RNA animal virus from negative-sense transcripts.

1994 • 58 citations

RNA promoters located on (-)-strands of a subviral RNA associated with turnip crinkle virus.

1997 • 50 citations

Structure and Function of the Hepatitis C Virus Internal Ribosome Entry Site

1995 • 35 citations

A novel dicistronic AAV vector using a short IRES segment derived from hepatitis C virus genome

1997 • 34 citations

Revertant analysis of J-K mutations in the encephalomyocarditis virus internal ribosomal entry site detects an altered leader protein

1996 • 32 citations

Effects of Defined Mutations in the 5′ Nontranslated Region of Rubella Virus Genomic RNA on Virus Viability and Macromolecule Synthesis

1998 • 30 citations

Tandem mengovirus 5' pseudoknots are linked to viral RNA synthesis, not poly(C)-mediated virulence

1996 • 17 citations