Parameters of cholesterol metabolism in the human hepatoma cell line, Hep-G2.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

The picomole determination of free and total cholesterol in cells in culture.

1978 • 440 citations

Regulation of Hepatic Metabolism

1986 • 394 citations

Apolipoprotein B: Structural and Metabolic Heterogeneity

1983 • 351 citations

Characterization of proteoliposomes containing apoprotein A-I: a new substrate for the measurement of lecithin: cholesterol acyltransferase activity.

1982 • 300 citations

Characterization of the asialoglycoprotein receptor in a continuous hepatoma line.

1981 • 273 citations

Isolation and characterization of polypeptides of human serum lipoproteins

1969 • 271 citations

Characterization of the major apolipoproteins secreted by two human hepatoma cell lines

1981 • 259 citations

Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro

1980 • 241 citations

A cholesteryl ester transfer complex in human plasma.

1980 • 214 citations

The Regulation of Hepatic Triglyceride Metabolism by Free Fatty Acids

1971 • 201 citations

Intrahepatic assembly of very low density lipoproteins. Effect of fatty acids on triacylglycerol and apolipoprotein synthesis.

1982 • 179 citations

Maintenance of cytochrome P-450 and metabolism of aflatoxin B1 in primary hepatocyte cultures

1977 • 178 citations

Purification and substrate specificity of lecithin—cholesterol acyl transferase from human plasma

1971 • 172 citations

Proteolytic processing of human preproapolipoprotein A-I. A proposed defect in the conversion of pro A-I to A-I in Tangier's disease.

1983 • 167 citations

The asialoglycoprotein receptor internalizes and recycles independently of the transferrin and insulin receptors

1983 • 161 citations

Bile acid secretion by cultured rat hepatocytes. Regulation by cholesterol availability.

1983 • 146 citations

Effects of estrogen on apolipoprotein secretion by the human hepatocarcinoma cell line, HepG2.

1985 • 134 citations

The metabolism in vitro of human low-density lipoprotein by the human hepatoma cell line Hep G2

1983 • 130 citations

Lipoprotein apolipoprotein synthesis by human hepatoma cells in culture

1981 • 130 citations

Regulation of cholesterol esterification and biosynthesis in monolayer cultures of normal adult rat hepatocytes.

1980 • 127 citations

Sex Steroid Modulation of Fatty Acid Utilization and Fatty Acid Binding Protein Concentration in Rat Liver

1980 • 124 citations

Hepatic cholesterol and bile acid metabolism in subjects with gallstones: comparative effects of short erm feeding of chenodeoxycholic and ursodeoxycholic acid.

1980 • 119 citations

Hepatology: A Textbook of Liver Disease

1983 • 113 citations

7-Ketocholesterol. Its effects on hepatic cholesterogenesis and its hepatic metabolism in vivo and in vitro.

1977 • 113 citations

Control of 3-hydroxy-3-methylglutaryl coenzyme A reductase by endogenously synthesized sterols in vitro and in vivo.

1977 • 110 citations

Determination of hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in man

1974 • 105 citations

Characterization of a human hepatic receptor for high density lipoproteins.

1985 • 104 citations

Secretion of very low density lipoproteins enriched in cholesteryl esters by cultured rat hepatocytes during simulation of intracellular cholesterol esterification

1980 • 99 citations

Determination of hepatic cholesterol 7α-hydroxylase activity in man

1974 • 97 citations

Effect of fatty acids on lipid and apoprotein secretion and association in hepatocyte cultures.

1983 • 97 citations

Catabolism of human low density lipoproteins by human hepatoma cell line HepG2

1984 • 94 citations

The pathway of the asialoglycoprotein-ligand during receptor-mediated endocytosis: a morphological study with colloidal gold/ligand in the human hepatoma cell line, Hep G2.

1983 • 78 citations

Utilization of exogenous free fatty acids for the production of very low density lipoprotein triglyceride by livers of carbohydrate-fed rats

1971 • 69 citations

Chromosomes of human hepatoma cell lines

1982 • 65 citations

Biosynthesis of human preapolipoprotein A-IV.

1984 • 64 citations

Effects of compactin, mevalonate and low-density lipoprotein on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2

1984 • 64 citations

Studies on the mechanisms of the rapid modulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in intact liver by mevalonolactone and 25-hydroxycholesterol

1980 • 54 citations

Hepatic cholesterol metabolism in normo- and hyperlipidemic patients with cholesterol gallstones.

1979 • 44 citations

Acyl-coenzyme A:Cholesterol acyltransferase in human liver. In vitro detection and some characteristics of the enzyme

1980 • 44 citations

Cholesterol can stimulate secretion of apolipoprotein B by cultured human hepatocytes

1985 • 40 citations

Lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity from the isolated perfused rabbit liver.

1984 • 40 citations

Splanchnic Metabolism of Plasma Apolipoprotein B

1981 • 40 citations

Promotion of sterol efflux and net transport by apolipoprotein E in lecithin: Cholesterol acyltransferase deficiency

1982 • 39 citations

Bile acid feeding and hepatic sterol metabolism: Effect of deoxycholic acid

1980 • 37 citations

Cholesterol Metabolism and Lipolytic Enzymes

1979 • 32 citations

Regulation of Low Density Lipoprotein Receptor Function in a Human Hepatoma Cell Line

1984 • 26 citations

Activity and Regulation of Low Density Lipoprotein Receptors in a Human Hepatoblastoma Cell Line

1984 • 25 citations

Precursor supply and hepatic enzyme activities as regulators of triacylglycerol synthesis in isolated hepatocytes and perfused liver

1982 • 23 citations

Acyl-Coenzyme A—Cholesterol Acyltransferase Activity in Human Liver

1979 • 20 citations

Cholesterol 7 alpha-hydroxylase from human liver: partial purification and reconstruction into defined phospholipid-cholesterol vesicles.

1981 • 15 citations

Some aspects of the control of hepatic cholesterol biosynthesis.

1977 • 12 citations