Characterization of the major apolipoproteins secreted by two human hepatoma cell lines

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Separation of plasma lipoproteins by density-gradient ultracentrifugation

1975 • 1,114 citations

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

1981 • 568 citations

Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver.

1976 • 543 citations

Formation of cholesteryl ester-rich particulate lipid during metabolism of chylomicrons

1970 • 496 citations

The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E.

1980 • 462 citations

Relative contributions by liver and intestine to individual plasma apolipoproteins in the rat.

1979 • 443 citations

Rapid hepatic clearance of the canine lipoproteins containing only the E apoprotein by a high affinity receptor. Identity with the chylomicron remnant transport process.

1980 • 428 citations

Regulation of the hepatic uptake of triglyceride-rich lipoproteins in the rat. Opposing effects of homologous apolipoprotein E and individual C apoproteins.

1980 • 372 citations

Determinants of hepatic uptake of triglyceride-rich lipoproteins and their remnants in the rat.

1980 • 365 citations

Effect of apoproteins on hepatic uptake of triglyceride emulsions in the rat.

1980 • 359 citations

Human apolipoprotein E isoprotein subclasses are genetically determined.

1981 • 341 citations

Hepatitis B surface antigen produced by a human hepatoma cell line

1976 • 323 citations

Hepatic catabolism of rat and human lipoproteins in rats treated with 17 alpha-ethinyl estradiol.

1979 • 322 citations

Rat Intestine Secretes Discoid High Density Lipoprotein

1978 • 264 citations

Very low density lipoprotein synthesis and secretion by cultured rat hepatocytes.

1979 • 238 citations

Chylomicron clearance in normal and hyperlipidemic man

1976 • 218 citations

The intestine as a source of apolipoprotein A1.

1977 • 210 citations

Biosynthesis of lymph and plasma lipoprotein apoproteins by isolated perfused rat liver and intestine

1973 • 207 citations

Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver.

1978 • 197 citations

Comparative Specificity of Microbial Proteinases

1974 • 195 citations

Isoprotein specificity in the hepatic uptake of apolipoprotein E and the pathogenesis of familial dysbetalipoproteinemia.

1980 • 191 citations

Quantitative studies of the metabolism of chylomicron triglycerides and cholesterol by liver and extrahepatic tissues of sheep and dogs

1971 • 173 citations

Apoproteins of the lipoproteins in a nonrecirculating perfusate of rat liver

1976 • 161 citations

Secretion of the arginine-rich and A-I apolipoproteins by the isolated perfused rat liver

1977 • 160 citations

Identification of circulating apolipoproteins synthesized by rat small intestine in vivo.

1978 • 147 citations

Intestinal apoproteins during fat absorption.

1978 • 135 citations

Lipogenesis and the synthesis and secretion of very low density lipoprotein by avian liver cells in nonproliferating monolayer culture. Hormonal effects.

1977 • 134 citations

Isoproteins of human apolipoprotein A-I demonstrated in plasma and intestinal organ culture.

1980 • 130 citations

Characterization of a unique human apolipoprotein E variant associated with type III hyperlipoproteinemia.

1980 • 123 citations

Biosynthesis of plasma apolipoproteins by rat small intestine without dietary or biliary fat.

1981 • 120 citations

Secretion of Cholesterol-Rich Lipoproteins by Perfused Livers of Hypercholesterolemic Rats

1979 • 110 citations

Binding, interiorization and degradation of cholesterol ester-labelled chylomicron-remnant particles by rat hepatocyte monolayers

1977 • 107 citations

Origin and transport of the A-I and arginine-rich apolipoproteins in mesenteric lymph of rats.

1978 • 107 citations

Rates of removal and degradation of chylomicron remnants by isolated perfused rat liver.

1978 • 96 citations

Quantification of the hepatic contribution to the catabolism of high density lipoproteins in rats.

1979 • 92 citations

High affinity binding of chylomicron remnants to rat liver plasma membranes.

1979 • 91 citations

Catabolism of the apoprotein of low density lipoproteins by the isolated perfused rat liver.

1978 • 88 citations

Identity of Very Low Density Lipoprotein Apoproteins of Plasma and Liver Golgi Apparatus

1970 • 80 citations

Preparative isoelectric focussing of apolipoproteins C and E from human very low density lipoproteins

1979 • 76 citations

Secretion of apolipoproteins in very low density and high density lipoproteins by perfused rat liver

1974 • 72 citations

Studies on the polymorphism of human apolipoprotein A-I

1980 • 65 citations

In vivo uptake of human and rat low density and high density lipoprotein by parenchymal and nonparenchymal cells from rat liver

1978 • 63 citations

The uptake of high density lipoprotein cholesteryl ester in the perfused rat liver.

1980 • 62 citations

Uptake and degradation of 125I-labelled high density lipoproteins in rat liver cells in vivo and in vitro

1979 • 62 citations

Apoprotein Synthesis by Human Duodenojejunal Mucosa

1978 • 61 citations

Production of apolipoproteins E and A-I by rat hepatocytes in primary culture

1980 • 55 citations

Lipoprotein secretion by isolated rat hepatocytes: characterization of the lipid-carrying particles and modulation of their release.

1980 • 44 citations

Low density lipoprotein receptors and catabolism in primary cultures of rabbit hepatocytes

1979 • 43 citations

Uptake and degradation of iodine-labelled chylomicron remnant particles by monolayers of rat hepatocytes

1978 • 40 citations

Comparison of the metabolism of chylomicrons and chylomicron remnants by the perfused liver

1978 • 30 citations