Chordin Is Required for the Spemann Organizer Transplantation Phenomenon in Xenopus Embryos

A molecular mechanism for the effect of lithium on development.

1996 • 2,270 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

1994 • 1,114 citations

FORMATION AND FUNCTION OF SPEMANN'S ORGANIZER

1997 • 836 citations

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

1996 • 757 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

Morpholino antisense oligomers: the case for an RNase H-independent structural type

1999 • 635 citations

Morpholino Oligos: Making Sense of Antisense?

2002 • 538 citations

The organizer factors Chordin and Noggin are required for mouse forebrain development

2000 • 528 citations

The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos

1988 • 521 citations

β-catenin translocation into nuclei demarcates the dorsalizing centers in frog and fish embryos

1996 • 516 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

The establishment of spemann's organizer and patterning of the vertebrate embryo

2000 • 424 citations

Cleavage of Chordin by Xolloid Metalloprotease Suggests a Role for Proteolytic Processing in the Regulation of Spemann Organizer Activity

1997 • 398 citations

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

1994 • 396 citations

The L45 loop in type I receptors for TGF‐β family members is a critical determinant in specifying Smad isoform activation

1998 • 390 citations

Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins

1997 • 350 citations

Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development

1999 • 338 citations

dino and mercedes, two genes regulating dorsal development in the zebrafish embryo

1996 • 325 citations

The early development of Xenopus laevisby P. Hausen and M. Riebesell, Springer-Verlag, 1991. £78.50 (vii + 142 pages) ISBN 3 540 53740 6

1993 • 323 citations

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.

1994 • 307 citations

Twisted gastrulation is a conserved extracellular BMP antagonist

2001 • 302 citations

Regional specification within the mesoderm of early embryos of Xenopus laevis

1987 • 286 citations

The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling

2000 • 278 citations

Genetics of polyploid Xenopus

1986 • 257 citations

Endogenous patterns of TGFβ superfamily signaling during early Xenopus development

2000 • 256 citations

Multiple Bone Morphogenetic Protein 1-related Mammalian Metalloproteinases Process Pro-lysyl Oxidase at the Correct Physiological Site and Control Lysyl Oxidase Activation in Mouse Embryo Fibroblast Cultures

2001 • 234 citations

The Biology of Xenopus

1996 • 212 citations

The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors

1998 • 205 citations

Twisted gastrulation can function as a BMP antagonist

2001 • 202 citations

Bmp Activity Gradient Regulates Convergent Extension during Zebrafish Gastrulation

2002 • 187 citations

Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling

2001 • 187 citations

Differenzierungspotenzen isolierter Teile der Urodelengastrula

1938 • 187 citations

Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems

2002 • 172 citations

Gene expression in the embryonic nervous system of Xenopus laevis.

1988 • 166 citations

Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos

1997 • 162 citations

Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling

2001 • 153 citations

Bone Morphogenetic Protein-1 Processes Probiglycan

2000 • 132 citations

Neural Induction in the Absence of Mesoderm: β-Catenin-Dependent Expression of Secreted BMP Antagonists at the Blastula Stage in Xenopus

2001 • 126 citations

Creation of a Sog Morphogen Gradient in the Drosophila Embryo

2002 • 108 citations

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

2002 • 106 citations

Differenzierungspotenzen isolierter Teile der Anurengastrula

1938 • 87 citations

The Role of BMP Signaling in Outgrowth and Patterning of the Xenopus Tail Bud

2001 • 83 citations

BMP1-Related Metalloproteinases Promote the Development of Ventral Mesoderm in Early Xenopus Embryos

1998 • 66 citations

Goosecoid Regulates the Neural Inducing Strength of the Mouse Node

1999 • 32 citations