Effects of purinergic and adrenergic antagonists in a rat model of painful peripheral neuropathy

Quantitative assessment of tactile allodynia in the rat paw

1994 • 6,953 citations

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

1992 • 3,001 citations

Efficient Analysis of Experimental Observations

1980 • 2,012 citations

THE MANAGEMENT OF PAIN

1954 • 1,496 citations

A P2X purinoceptor expressed by a subset of sensory neurons

1995 • 1,014 citations

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

1995 • 988 citations

Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain

1994 • 803 citations

Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia

1993 • 730 citations

Heritability of nociception I: Responses of 11 inbred mouse strains on 12 measures of nociception

1999 • 648 citations

A hypothesis on the physiological basis for causalgia and related pains

1986 • 566 citations

Causalgia and Other Reflex Sympathetic Dystrophies

1973 • 481 citations

Distinct ATP receptors on pain-sensing and stretch-sensing neurons

1997 • 452 citations

Comparison of three rodent neuropathic pain models

1997 • 407 citations

Suramin: an anticancer drug with a unique mechanism of action.

1989 • 370 citations

Purinergic receptors: their role in nociception and primary afferent neurotransmission

1996 • 356 citations

Suramin: With Special Reference to Onchocerciasis

1978 • 291 citations

Recent research on the biological activity of suramin.

1993 • 281 citations

Painful peripheral states and sympathetic blocks.

1978 • 276 citations

INTRAVENOUS REGIONAL SYMPATHETIC BLOCK WITH GUANETHIDINE

1974 • 267 citations

Noradrenaline-ATP co-transmission in the sympathetic nervous system

1991 • 264 citations

A unifying purinergic hypothesis for the initiation of pain

1996 • 241 citations

Heritability of nociception II. ‘Types’ of nociception revealed by genetic correlation analysis

1999 • 236 citations

URINARY INFECTION IN THE TWO SEXES

1966 • 235 citations

Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathic injury

1999 • 214 citations

Effects of sympathectomy on a rat model of peripheral neuropathy

1993 • 212 citations

Sympathetic and afferent somata projecting in hindlimb nerves and the anatomical organization of the lumbar sympathetic nervous system of the rat

1988 • 199 citations

Noradrenaline and ATP as cotransmitters in sympathetic nerves

1990 • 191 citations

Effects of sympathectomy in a model of causalgiform pain produced by partial sciatic nerve injury in rats

1991 • 186 citations

Sympathetic sprouting in the dorsal root ganglia of the injured peripheral nerve in a rat neuropathic pain model

1996 • 183 citations

Acute nociception mediated by hindpaw P2X receptor activation in the rat

1997 • 180 citations

The Chemical Neuroanatomy of Sympathetic Ganglia

1993 • 175 citations

The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat

1999 • 174 citations

Abnormalities of sympathetic innervation in the area of an injured peripheral nerve in a rat model of neuropathic pain

1993 • 162 citations

Rapid sprouting of sympathetic axons in dorsal root ganglia of rats with a chronic constriction injury

1997 • 156 citations

Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay.

1996 • 154 citations

Sympathectomy alleviates mechanical allodynia in an experimental animal model for neuropathy in the rat

1991 • 153 citations

Causalgia

1967 • 146 citations

Anatomical evidence for genetic differences in the innervation of the rat spinal cord by noradrenergic locus coeruleus neurons

1992 • 130 citations

Sensory and sympathetic contributions to nerve injury-induced sensory abnormalities in the rat

1995 • 108 citations

Different strains and substrains of rats show different levels of neuropathic pain behaviors

1999 • 104 citations

Effects of guanethidine on sensitization to natural stimuli and self-mutilating behaviour in rats with a peripheral neuropathy

1991 • 102 citations

Lumbar sympathectomy failed to reverse mechanical allodynia- and hyperalgesia-like behavior in rats with L5 spinal nerve injury

1999 • 94 citations

Antinociceptive effect of intrathecally administered P2-purinoceptor antagonists in rats

1994 • 92 citations

The noradrenergic innervation of the spinal cord: differences between two substrains of Sprague-Dawley rats determined using retrograde tracers combined with immunocytochemistry

1991 • 91 citations

Peripheral adenosine 5′-triphosphate enhances nociception in the formalin test via activation of a purinergic p2X receptor

1997 • 89 citations

Adenosine triphosphate-evoked vascular changes in human skin: Mechanism of action

1981 • 78 citations

Small noradrenergic storage vesicles isolated from rat vas deferens--biochemical and morphological characterization.

1980 • 68 citations

Present status of chemotherapy and chemoprohylaxis of human trypanosomiasis in the Eastern Hemisphere

1980 • 63 citations

Strain differences in adrenergic sensitivity of neuropathic pain behaviors in an experimental rat model

1997 • 58 citations

Adrenergic sensitivity of the sensory receptors modulating mechanical allodynia in a rat neuropathic pain model

1999 • 56 citations

Intrathecal Neostigmine, but Not Sympathectomy, Relieves Mechanical Allodynia in a Rat Model of Neuropathic Pain

1998 • 48 citations

Mechanical hyperalgesia after spinal nerve ligation in rat is not reversed by intraplantar or systemic administration of adrenergic antagonists

1999 • 46 citations

Norepinephrine Rekindles Mechanical Allodynia in Sympathectomized Neuropathic Rat

1995 • 38 citations

Purinergic cotransmission: sympathetic nerves

1996 • 36 citations

Noradrenaline release from rat sympathetic neurons evoked by P2-purinoceptor activation

1994 • 36 citations

INTERACTION BETWEEN ADENOSINE TRIPHOSPHATE AND NORADRENALINE IN THE ISOLATED VAS DEFERENS OF THE GUINEA‐PIG

1980 • 35 citations

THE EFFECTS OF ADENINE NUCLEOTIDES ON CUTANEOUS AFFERENT NERVE ACTIVITY

1978 • 34 citations

Organomegaly and histopathology in an animal model of mucopolysaccharidosis induced by suramin

1982 • 29 citations

Analgesic activity of anticancer agent suramin

1992 • 29 citations

Guanethidine for reflex sympathetic dystrophy.

1994 • 8 citations