Effects of sympathectomy in a model of causalgiform pain produced by partial sciatic nerve injury in rats

The Pharmacological Basis of Therapeutics

1986 • 2,365 citations

A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury

1990 • 1,819 citations

Ongoing activity in peripheral nerves: the physiology and pharmacology of impulses originating from a neuroma

1975 • 610 citations

A hypothesis on the physiological basis for causalgia and related pains

1986 • 566 citations

Injuries of Nerves and their Consequences

1872 • 527 citations

Causalgia and Other Reflex Sympathetic Dystrophies

1973 • 481 citations

Reflex Sympathetic Dystrophy

1987 • 381 citations

Two modes of cutaneous reinnervation following peripheral nerve injury

1979 • 319 citations

Development of ongoing activity, mechanosensitivity, and adrenaline sensitivity in severed peripheral nerve axons

1981 • 289 citations

Noradrenaline hyperalgesia is mediated through interaction with sympathetic postgahglionic neurone terminals rather than activation of primary afferent nociceptors

1986 • 286 citations

Painful peripheral states and sympathetic blocks.

1978 • 276 citations

Activation of myelinated afferents ending in a neuroma by stimulation of the sympathetic supply in the rat

1981 • 254 citations

Psychophysical observations on patients with neuropathic pain relieved by a sympathetic block

1989 • 249 citations

Ephaptic transmission in chronically damaged peripheral nerves

1979 • 241 citations

Ongoing activity in peripheral nerve: Injury discharge

1974 • 240 citations

Nerve pathophysiology and mechanisms of pain in causalgia

1983 • 236 citations

A new method of destroying adrenergic nerves in adult animals using guanethidine

1971 • 222 citations

A-fibers mediate mechanical hyperesthesia and allodynia and C-fibers mediate thermal hyperalgesia in a new model of causalgiform pain disorders in rats

1990 • 221 citations

The production and prevention of experimental anesthesia dolorosa

1979 • 219 citations

Classification of chronic pain

1986 • 215 citations

Sensory Functions of the Skin in Primates

1976 • 190 citations

Pain Mechanisms: A Physiologic Interpretation of Causalgia and its Related States

1944 • 171 citations

POST-TRAUMATIC PAIN AND THE CAUSALGIC SYNDROME

1944 • 168 citations

Ectopic adrenergic sensitivity in damaged peripheral nerve axons in the rat

1981 • 160 citations

Unmyelinated nociceptive units in two skin areas of the rat

1983 • 149 citations

Causalgia

1967 • 146 citations

Spontaneous impulse generation in normal and denervated dorsal root ganglia: Sensitivity to alpha-adrenergic stimulation and hypoxia

1984 • 143 citations

Sympathetic facilitation of sustained discharges of polymodal nociceptors

1989 • 140 citations

PRELIMINARY OBSERVATIONS ON THE PATHOPHYSIOLOGY OF HYPERALGESIA IN THE CAUSALGIC PAIN SYNDROME

1976 • 136 citations

Neural activity originating from a neuroma in the baboon

1985 • 122 citations

Activation of unmyelinated afferents in chronically lesioned nerves by adrenaline and excitation of sympathetic efferents in the cat

1987 • 106 citations

Sympathetic Activation of A-Delta Nociceptors

1985 • 104 citations

Activation of fibers via experimentally produced stump neuromas of skin nerves: Ephaptic transmission or retrograde sprouting?

1982 • 102 citations

Afterdischarge and interactions among fibers in damaged peripheral nerve in the rat

1987 • 99 citations

Effects of injury on trigeminal and spinal somatosensory systems

1988 • 98 citations

Electrical stimulation of the upper thoracic portion of the sympathetic chain in man.

1948 • 86 citations

La Chirurgie de la Douleur.

1939 • 77 citations

Collateral sprouting in skin and sensory recovery after nerve injury in man

1987 • 76 citations

Primary afferent and spinal sensory neurons that respond to brief pulses of intense infrared laser radiation: A preliminary survey in rats

1982 • 75 citations

Biochemical and functional evaluation of the sympathectomy produced by the administration of guanethidine to newborn rats.

1975 • 73 citations

Reflex sympathetic dystrophies and algodystrophies: historical and pathogenic considerations

1987 • 64 citations

Selectivity of neuronal degeneration produced by chronic guanethidine treatment

1977 • 48 citations

La Chirurgie de la Douleur.

1940 • 46 citations

Neurophysiological Analysis of Efferent Sympathetic and Afferent Fibers in Skin Nerves with Experimentally Produced Neuromata

1981 • 42 citations

Discharge of tritium-labeled guanethidine by sympathetic nerve stimulation as evidence that guanethidine is a false transmitter

1966 • 41 citations

Abnormal and collateral innervations of sympathetic and peripheral sensory fields associated with a case of causalgia

1984 • 38 citations

Reproductive physiology and behavior in the male rat following acute and chronic peripheral adrenergic depletion by guanethidine

1985 • 31 citations

Lack of sensitization of primary afferent receptors by prostaglandins in a rat model of causalgic chronic pains

1988 • 26 citations

Does sympathetic activity modify afferent inflow at the receptor level in man?

1983 • 25 citations

Factors affecting the action of guanethidine on adrenergic neurones

1971 • 22 citations

Guanethidine adrenergic neuropathy: an animal model of selective autonomic neuropathy

1988 • 21 citations

Contrasting time course of catecholamine accumulation and of spontaneous discharge in experimental neuromas in the rat

1988 • 18 citations

Augmentation of the Pressor Response to Guanethedine by Inhibition of Catechol O-Methyltransferase

1961 • 12 citations

A STUDY OF THE SYMPATHOMIMETIC ACTION OF GUANETHIDINE ON THE ISOLATED ANOCOCCYGEUS MUSCLE OF THE RAT

1978 • 9 citations