Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid

The retinoids—Biology, chemistry and medicine

1996 • 1,192 citations

STRUCTURE AND FUNCTION OF THE MANNOSE 6-PHOSPHATE/INSULINLIKE GROWTH FACTOR II RECEPTORS

1992 • 1,056 citations

The Retinoids-Biology, Chemistry and Medicine

1994 • 987 citations

Insulin-like growth factor II receptor as a multifunctional binding protein

1987 • 858 citations

Retinoids and their receptors in differentiation, embryogenesis, and neoplasia

1991 • 856 citations

Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.

1994 • 593 citations

Vitamin A and Retinoids in Health and Disease

1984 • 560 citations

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.

1991 • 521 citations

[8] Photoaffinity labeling

1977 • 495 citations

Mouse Mutants Lacking the Type 2 IGF Receptor (IGF2R) Are Rescued from Perinatal Lethality inIgf2andIgf1rNull Backgrounds

1996 • 479 citations

Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene

1994 • 471 citations

Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha.

1996 • 467 citations

A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate

1988 • 363 citations

M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity

1995 • 352 citations

Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis.

1989 • 333 citations

Studies on the mode of action of excess of vitamin A. 6. Lysosomal protease and the degradation of cartilage matrix

1963 • 292 citations

N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid.

1993 • 249 citations

Activation of Retinoid X Receptors Induces Apoptosis in HL-60 Cell Lines

1995 • 247 citations

Antiarrhythmic Effects of Polyunsaturated Fatty Acids

1996 • 230 citations

M6P/IGF2 receptor: a candidate breast tumor suppressor gene.

1996 • 205 citations

Direct demonstration of rapid insulin-like growth factor II Receptor internalization and recycling in rat adipocytes. Insulin stimulates 125I-insulin-like growth factor II degradation by modulating the IGF-II receptor recycling process.

1985 • 203 citations

Biochemical evidence that the type II insulin-like growth factor receptor is identical to the cation-independent mannose 6-phosphate receptor.

1988 • 190 citations

Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity

1992 • 190 citations

Identification and characterization of cells deficient in the mannose 6-phosphate receptor: evidence for an alternate pathway for lysosomal enzyme targeting.

1983 • 186 citations

The insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor mediates IGF-II-induced motility in human rhabdomyosarcoma cells.

1992 • 137 citations

Serum Form of the Rat Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor Is Truncated in the Carboxyl-terminal Domain

1989 • 114 citations

Characterization of a phosphorylated pentasaccharide isolated from Hansenula holstii NRRL Y-2448 phosphomannan

1973 • 86 citations

Characterization of a vitamin D3-resistant MCF-7 cell line.

1996 • 73 citations

[34] Membrane receptor for phosphomannosyl residues

1982 • 65 citations

Developmental expression of the IGF‐II/mannose 6‐phosphate receptor

1993 • 62 citations

Retro-retinoids in regulated cell growth and death.

1996 • 60 citations

Comparison of the effects of vitamin A and its analogs upon rabbit ear cartilage in organ culture and upon growth of the vitamin A-deficient rat

1974 • 55 citations

Soluble Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor Carries Multiple High Molecular Weight Forms of Insulin-like Growth Factor II in Fetal Bovine Serum

1995 • 54 citations

Expression of human cation-independent mannose 6-phosphate receptor cDNA in receptor-negative mouse P388D1 cells following gene transfer.

1988 • 51 citations

Deficient transforming growth factor-beta1 activation and excessive insulin-like growth factor II (IGFII) expression in IGFII receptor-mutant tumors.

1997 • 47 citations

[11] General principles for photoaffinity labeling of peptide hormone receptors

1985 • 46 citations

Rescue of the limb deformity in Hammertoe mutant mice by retinoic acid-induced cell death

1997 • 45 citations

Induction of apoptosis and cathepsin D in limbs exposed in vitro to an activated analog of cyclophosphamide

1995 • 34 citations

Photoaffinity labeling of retinoic acid-binding proteins.

1995 • 25 citations

Identification of receptors for insulin-like growth factor II in two insulin-like growth factor II producing cell lines

1986 • 24 citations

The effect of mannose6-phosphate on the turnover of cell surface glycosaminoglycans*1

1983 • 20 citations

Physicochemical Parameters Affecting the Charcoal Adsorption Assay for Quantitative Retinoid-Binding Measurement

1994 • 9 citations