Role of EP3 and EP4 prostaglandin receptors in reorganization of the cytoskeleton in mature human osteoclasts.

Prostanoid Receptors: Structures, Properties, and Functions

1999 • 2,395 citations

Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor

2000 • 811 citations

The cell biology of osteoclast function

2000 • 694 citations

Calcium-mediated Translocation of Cytosolic Phospholipase A2 to the Nuclear Envelope and Endoplasmic Reticulum

1995 • 469 citations

A New Member of Tumor Necrosis Factor Ligand Family, ODF/OPGL/TRANCE/RANKL, Regulates Osteoclast Differentiation and Function

1999 • 464 citations

The Effect of Calcium-Regulating Hormones and Prostaglandins on Bone Resorption by Osteoclasts Disaggregated from Neonatal Rabbit Bones*

1985 • 419 citations

Identification and Characterization of a Prostaglandin Transporter

1995 • 400 citations

The Role of Prostaglandin E Receptor Subtypes (EP1, EP2, EP3, and EP4) in Bone Resorption: An Analysis Using Specific Agonists for the Respective EPs

2000 • 382 citations

Subcellular Localization of Prostaglandin Endoperoxide H Synthases-1 and -2 by Immunoelectron Microscopy

1998 • 338 citations

The role of prostaglandins in the regulation of bone metabolism.

1995 • 293 citations

Cortical hyperostosis following long-term administration of prostaglandin E1 in infants with cyanotic congenital heart disease

1980 • 277 citations

Pathogenesis of bone erosions in rheumatoid arthritis

2000 • 252 citations

Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro

1991 • 245 citations

Nuclear localization of prostaglandin E ₂ receptors

1998 • 240 citations

Localization of Functional Prostaglandin E2 Receptors EP3 and EP4 in the Nuclear Envelope

1999 • 227 citations

G Protein–Coupled Prostanoid Receptors and the Kidney

2001 • 225 citations

Impaired Bone Resorption to Prostaglandin E2 in Prostaglandin E Receptor EP4-knockout Mice

2000 • 215 citations

The osteoclast clear zone is a specialized cell-extracellular matrix adhesion structure

1995 • 212 citations

Prostaglandin E2, Interleukin 1α, and Tumor Necrosis Factor-α Increase Human Osteoclast Formation and Bone Resorption in Vitro*

1998 • 176 citations

Prostaglandin E2 Induces Expression of Receptor Activator of Nuclear Factor–κB Ligand/Osteoprotegrin Ligand on Pre-B Cells: Implications for Accelerated Osteoclastogenesis in Estrogen Deficiency

2000 • 170 citations

Prostaglandin synthesis by fetal rat bone in vitro: Evidence for a role of prostacyclin

1979 • 155 citations

Cloning and characterization of an abundant subtype of the human calcitonin receptor.

1994 • 151 citations

Fluid Shear Stress Stimulates Prostaglandin and Nitric Oxide Release in Bone Marrow-Derived Preosteoclast-like Cells

2000 • 142 citations

The distribution of podosomes in osteoclasts cultured on bone laminae: Effect of retinol

1988 • 135 citations

Crucial Involvement of the EP4 Subtype of Prostaglandin E Receptor in Osteoclast Formation by Proinflammatory Cytokines and Lipopolysaccharide

2000 • 124 citations

Systemic administration of an anabolic dose of PGE2 in young rats increases the osteogenic capacity of bone marrow

1997 • 122 citations

Inhibition of osteoclastic motility by prostaglandins I₂, E₁, E₂ and 6‐oxo‐E₁

1983 • 107 citations

Impaired Bone Resorption by Lipopolysaccharide In Vivo in Mice Deficient in the Prostaglandin E Receptor EP4 Subtype

2000 • 92 citations

Insulin-like growth factor-I stimulates gonadotrophin production from eel pituitary cells: a possible metabolic signal for induction of puberty

1998 • 92 citations

Prostaglandin E2 Directly Inhibits Bone-Resorbing Activity of Isolated Mature Osteoclasts Mainly Through the EP4 Receptor

2000 • 77 citations

Regulation of cytosolic free calcium in isolated rat osteoclasts by calcitonin

1992 • 72 citations

Calcium homeostasis and hypercalciuria in hyperprostaglandin E syndrome

1992 • 69 citations

Prostaglandin E2 Increases the Skeletal Response to Mechanical Loading

1997 • 67 citations

Diclofenac sodium inhibits bone resorption in postmenopausal women

1994 • 52 citations

Adenosine inhibits actin dynamics in human neutrophils: Evidence for the involvement of cAMP

1998 • 44 citations

Effects of prostacyclin and prostaglandin E1 (PGE1) on bone resorption in the presence and absence of parathyroid hormone

1986 • 44 citations

Mechanisms of Osteoclast Dysfunction in Human Osteopetrosis: Abnormal Osteoclastogenesis and Lack of Osteoclast-Specific Adhesion Structures

1999 • 44 citations

Role of Actin Cytoskeleton in Prostaglandin-Induced Protection against Ethanol in an Intestinal Epithelial Cell Line

2000 • 35 citations

Two Isoforms of Prostaglandin EP3 Receptor Exhibiting Constitutive Activity and Agonist-Dependent Activity in Rho-Mediated Stress Fiber Formation

1997 • 34 citations

Prostaglandin E2 initially inhibits and then stimulates bone resorption in isolated rabbit osteoclast cultures

1989 • 32 citations

Regulation of Differentiated Osteoclasts

2000 • 30 citations

Characterization of the prostaglandin receptors in human osteoblasts in culture

2001 • 30 citations

Immobilization increases bone prostaglandin E: Effect of acetylsalicylic acid on disuse osteoporosis studied in dogs

1991 • 30 citations

The effect of sodium salicylate on the osteoclast-like cell formation and bone resorption in a mouse bone marrow culture

1994 • 24 citations

Long-term effect of naproxen on cancellous bone in ovariectomized rats

1992 • 16 citations

[Regulation of osteoclastic resorption by prostanoids in vivo].

1993 • 1 citations