Mechanism-based inhibition of dopamine beta-monooxygenase by aldehydes and amides.

[6] Statistical analysis of enzyme kinetic data

1979 • 2,002 citations

The Enzymatic Conversion of 3,4-Dihydroxyphenylethylamine to Norepinephrine

1960 • 435 citations

Substrates and inhibitors of dopamine-β-oxidase

1962 • 182 citations

Mechanism of dopamine-beta-hydroxylation. Semidehydroascorbate as the enzyme oxidation product of ascorbate.

1981 • 119 citations

Secondary isotope effects and structure-reactivity correlations in the dopamine .beta.-monooxygenase reaction: evidence for a chemical mechanism

1985 • 105 citations

Enolisation of Simple Carbonyl Compounds and Related Reactions

1982 • 97 citations

Direct spectrophotometric detection of ascorbate free radical formed by dopamine β-monooxygenase and by ascorbate oxidase

1980 • 92 citations

Evidence for two copper atoms/subunit in dopamine beta-monooxygenase catalysis.

1984 • 80 citations

Kinetic and spectroscopic studies of the interaction of copper with dopamine beta-hydroxylase.

1984 • 76 citations

Mechanism of modulation of dopamine .beta.-monooxygenase by pH and fumarate as deduced from initial rate and primary deuterium isotope effect studies

1983 • 75 citations

Asymmetric sulfoxidation by dopamine .beta.-hydroxylase, an oxygenase heretofore considered specific for methylene hydroxylation

1980 • 75 citations

Magnitude of intrinsic isotope effects in the dopamine .beta.-monooxygenase reaction

1983 • 66 citations

Simple enols. 2. Kinetics and mechanism of the ketonization of vinyl alcohol

1982 • 61 citations

Olefin oxygenation and N-dealkylation by dopamine .beta.-monooxygenase: catalysis and mechanism-based inhibition

1985 • 57 citations

3-Phenylpropenes as mechanism-based inhibitors of dopamine .beta.-hydroxylase: evidence for a radical mechanism

1985 • 44 citations

Dopamine .beta.-hydroxylase: activity and inhibition in the presence of .beta.-substituted phenethylamines

1982 • 39 citations

The Kinetics of the Cupric Ion Oxidation of α-Hydroxyacetophenone¹

1965 • 39 citations

Dopamine-B-hydroxylase: Suicide inhibition by the novel olefinic substrate, 1-phenyl-1-aminomethylethene

1983 • 35 citations

Dopamine beta-hydroxylase. Demonstration of enzymatic ketonization of the product enantiomer S-octopamine.

1981 • 33 citations

Mechanism-based inhibitors of dopamine .beta.-hydroxylase containing acetylenic or cyclopropyl groups

1985 • 32 citations

Mechanism-based inactivation of dopamine beta-monooxygenase by beta-chlorophenethylamine.

1984 • 28 citations

Inactivation of dopamine β-monooxygenase by hydrogen peroxide and by ascorbate

1980 • 25 citations

Dopamine beta-hydroxylase. Inactivation by a suicide substrate.

1980 • 25 citations

Alternate substrates of dopamine beta-hydroxylase. I. Kinetic investigations of benzyl cyanides as substrates and inhibitors.

1984 • 23 citations

Alternate substrates of dopamine beta-hydroxylase. III. Stoichiometry of the inactivation reaction with benzyl cyanides and spectroscopic investigations.

1984 • 18 citations

An acetylenic mechanism-based inhibitor of dopamine beta-hydroxylase.

1984 • 9 citations

Alternate substrates of dopamine beta-hydroxylase. II. Inhibition by benzyl cyanides and reactivation of inhibited enzyme.

1984 • 9 citations