The languages of bacteria

Quorum Sensing in Bacteria

2001 • 4,724 citations

MICROBIAL BIOFILMS

1995 • 4,253 citations

The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm

1998 • 3,303 citations

CENSUS AND CONSENSUS IN BACTERIAL ECOSYSTEMS: The LuxR-LuxI Family of Quorum-Sensing Transcriptional Regulators

1996 • 1,203 citations

Bacterial Quorum Sensing in Pathogenic Relationships

2000 • 1,102 citations

Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa

1999 • 1,056 citations

The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule

2001 • 991 citations

Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes

1997 • 987 citations

Biofilms, the customized microniche

1994 • 978 citations

How bacteria talk to each other: regulation of gene expression by quorum sensing

1999 • 978 citations

Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production

1999 • 945 citations

Bacterial bioluminescence: Isolation and genetic analysis of functions from Vibrio fischeri

1983 • 873 citations

Expression of Pseudomonas aeruginosa Virulence Genes Requires Cell-to-Cell Communication

1993 • 854 citations

Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa

1997 • 852 citations

Bacterial Interference Caused by Autoinducing Peptide Variants

1997 • 792 citations

AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora

2000 • 786 citations

Quorum sensing by peptide pheromones and two‐component signal‐transduction systems in Gram‐positive bacteria

1997 • 773 citations

Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling

1996 • 743 citations

Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence

1993 • 741 citations

Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi

1997 • 737 citations

A hierarchical quorum‐sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary‐phase sigma factor RpoS

1996 • 692 citations

Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway

1994 • 681 citations

Bacterial bioluminescence: its control and ecological significance

1979 • 641 citations

Identification of genes controlled by quorum sensing in Pseudomonas aeruginosa

1999 • 637 citations

Cell density control of staphylococcal virulence mediated by an octapeptide pheromone.

1995 • 634 citations

Identification of genes and gene products necessary for bacterial bioluminescence.

1984 • 615 citations

Quorum sensing in Escherichia coli and Salmonella typhimurium

1998 • 615 citations

Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein

1999 • 604 citations

Acyl homoserine-lactone quorum-sensing signal generation

1999 • 570 citations

Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa.

1995 • 557 citations

Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family

1995 • 550 citations

Diffusion of autoinducer is involved in regulation of the Vibrio fischeri luminescence system

1985 • 547 citations

Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus

1988 • 545 citations

Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli

1999 • 510 citations

Conjugation factor of Agrobacterium tumefaciens regulates Ti plasmid transfer by autoinduction

1993 • 504 citations

A LuxR-LuxI type regulatory system activates Agrobacterium Ti plasmid conjugal transfer in the presence of a plant tumor metabolite

1994 • 479 citations

Metabolism of Acyl-Homoserine Lactone Quorum-Sensing Signals by Variovorax paradoxus

2000 • 478 citations

The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.

1993 • 469 citations

Biochemical and genetic characterization of a competence pheromone from B. subtilis

1994 • 457 citations

Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence

1999 • 448 citations

Activation of alpha-toxin translation in Staphylococcus aureus by the trans-encoded antisense RNA, RNAIII.

1995 • 448 citations

Theagr P2 operon: An autocatalytic sensory transduction system inStaphylococcus aureus

1995 • 440 citations

Agrobacterium conjugation and gene regulation by N-acyl-L-homoserine lactones

1993 • 435 citations

QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa

2001 • 431 citations

Enzymatic Synthesis of a Quorum-Sensing Autoinducer Through Use of Defined Substrates

1996 • 406 citations

GENETIC NETWORKS CONTROLLING THE INITIATION OF SPORULATION AND THE DEVELOPMENT OF GENETIC COMPETENCE IN BACILLUS SUBTILIS

1995 • 406 citations

Purification and Structural Identification of an Autoinducer for the Luminescence System of Vibrio harveyi

1989 • 398 citations

Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide

1999 • 397 citations

BACTERIAL BIOLUMINESCENCE

1977 • 362 citations

A genetic analysis of the function of LuxO, a two‐component response regulator involved in quorum sensing in Vibrio harveyi

1999 • 362 citations

Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor

1998 • 359 citations

Quorum Sensing in Burkholderia cepacia : Identification of the LuxRI Homologs CepRI

1999 • 351 citations

The mechanism of action of S-adenosylhomocysteinase.

1979 • 347 citations

Burkholderia cepacia: medical, taxonomic and ecological issues

1996 • 337 citations

Agrobacterium tumefaciens T-complex transport apparatus: a paradigm for a new family of multifunctional transporters in eubacteria

1997 • 322 citations

LESSONS FROM A COOPERATIVE, BACTERIAL-ANIMAL ASSOCIATION: The Vibrio fischeri–Euprymna scolopes Light Organ Symbiosis

1996 • 315 citations

Regulation of quorum sensing in Vibrio harveyi by LuxO and Sigma‐54

2000 • 313 citations

Multiple protein-aspartate phosphatases provide a mechanism for the integration of diverse signals in the control of development in B. subtilis

1994 • 295 citations

Agrobacterium-plant cell DNA transport: have virulence proteins, will travel.

1996 • 280 citations

Purification and characterization of an extracellular peptide factor that affects two different developmental pathways in Bacillus subtilis.

1996 • 267 citations

Phenazine antibiotic biosynthesis in Pseudomonas aureofaciens 30-84 is regulated by PhzR in response to cell density

1994 • 249 citations

Sequence and Function of LuxU: a Two-Component Phosphorelay Protein That Regulates Quorum Sensing in Vibrio harveyi

1999 • 245 citations

An Exported Peptide Functions Intracellularly to Contribute to Cell Density Signaling in B. subtilis

1997 • 242 citations

Synergistic binding of the Vibrio fischeri LuxR transcriptional activator domain and RNA polymerase to the lux promoter region.

1994 • 239 citations

comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis

1995 • 229 citations

TraI, a LuxI homologue, is responsible for production of conjugation factor, the Ti plasmid N-acylhomoserine lactone autoinducer.

1994 • 221 citations

Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis.

1997 • 205 citations

Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes

2001 • 197 citations

The C-terminal region of the Vibrio fischeri LuxR protein contains an inducer-independent lux gene activating domain.

1991 • 197 citations

Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis.

1995 • 196 citations

A peptide export–import control circuit modulating bacterial development regulates protein phosphatases of the phosphorelay

1997 • 189 citations

Quorum sensing in Vibrio fischeri: essential elements for activation of the luminescence genes

1997 • 183 citations

The ins and outs of peptide signaling

1998 • 177 citations

A genetic analysis of the functions of LuxN: a two‐component hybrid sensor kinase that regulates quorum sensing in Vibrio harveyi

2000 • 175 citations

Sequence and function of LuxO, a negative regulator of luminescence in Vibrio harveyi

1994 • 173 citations

Inhibition of virulence factor expression in Staphylococcus aureus by the Staphylococcus epidermidis agr pheromone and derivatives

1999 • 168 citations

An Exclusive Contract: Specificity in the Vibrio fischeri-Euprymna scolopes Partnership

2000 • 166 citations

Cloning of a chromosomal locus (exp) which regulates the expression of several exoprotein genes in Staphylococcus aureus

1988 • 164 citations

Nucleotide sequence of the regulatory locus controlling expression of bacterial genes for bioluminescence

1987 • 154 citations

Opine catabolism and conjugal transfer of the nopaline Ti plasmid pTiC58 are coordinately regulated by a single repressor.

1992 • 152 citations

Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa

1994 • 150 citations

Activity of the Agrobacterium Ti plasmid conjugal transfer regulator TraR is inhibited by the product of the traM gene

1995 • 148 citations

Quorum sensing in Vibrio fischeri: evidence that S-adenosylmethionine is the amino acid substrate for autoinducer synthesis

1996 • 144 citations

Genetic dissection of DNA binding and luminescence gene activation by the Vibrio fischeri LuxR protein

1992 • 143 citations

In Vivo Evidence that S -Adenosylmethionine and Fatty Acid Synthesis Intermediates Are the Substrates for the LuxI Family of Autoinducer Synthases

1998 • 136 citations

Cloning and nucleotide sequence of luxR, a regulatory gene controlling bioluminescence in Vibrio harveyi

1990 • 132 citations

Critical regions of the Vibrio fischeri luxR protein defined by mutational analysis

1990 • 131 citations

[3] Quorum sensing signals in development of Pseudomonas aeruginosa biofilms

1999 • 120 citations

Acylhomoserine Lactone Synthase Activity of the Vibrio fischeri AinS Protein

1999 • 116 citations

Biosynthesis of methionine.

1956 • 106 citations

Identification of a locus controlling expression of luminescence genes in Vibrio harveyi

1989 • 105 citations

Evidence for a Signaling System in Helicobacter pylori : Detection of a luxS -Encoded Autoinducer

2000 • 102 citations

Shigella flexneri LuxS Quorum-Sensing System Modulates virB Expression but Is Not Essential for Virulence

2001 • 98 citations

The Antiactivator TraM Interferes with the Autoinducer-dependent Binding of TraR to DNA by Interacting with the C-terminal Region of the Quorum-sensing Activator

2000 • 85 citations

Localization of OccR‐activated and TraR‐activated promoters that express two ABC‐type permeases and the traR gene of Ti plasmid pTiR10

1996 • 83 citations

Characterization of RecombinantEschericha coli5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase: Analysis of Enzymatic Activity and Substrate Specificity

1996 • 77 citations

Escherichia coli S-adenosylhomocysteine/5′-methylthioadenosine nucleosidase. Purification, substrate specificity and mechanism of action

1985 • 74 citations

Control of Cellular Development in Sporulating Bacteria by the Phosphorelay Two-Component Signal Transduction System

2014 • 67 citations

S-Ribosylhomocysteine Cleavage Enzyme from Escherichia coli

1968 • 60 citations

Involvement of the RNA Polymerase α-Subunit C-Terminal Domain in LuxR-Dependent Activation of the Vibrio fischeri Luminescence Genes

1999 • 60 citations

Pseudomonas cepacia: pulmonary infection in patients with cystic fibrosis

1993 • 46 citations

Cloning, Characterization, andSequencing ofan Accessory Gene Regulator (agr) inStaphylococcus aureus

1988 • 40 citations

Intragenic suppression of aluxRmutation: Characterization of an autoinducer-independent LuxR

1995 • 23 citations

Methylthioadenosine

1983 • 21 citations