Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase

1974 • 9,660 citations

A Broad Host Range Mobilization System for In Vivo Genetic Engineering: Transposon Mutagenesis in Gram Negative Bacteria

1983 • 7,336 citations

A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE

1952 • 6,430 citations

MICROBIAL BIOFILMS

1995 • 4,253 citations

The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm

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A new medium for the enumeration and subculture of bacteria from potable water

1985 • 2,190 citations

Cellular Control of the Synthesis and Activity of the Bacterial Luminescent System

1970 • 1,230 citations

CENSUS AND CONSENSUS IN BACTERIAL ECOSYSTEMS: The LuxR-LuxI Family of Quorum-Sensing Transcriptional Regulators

1996 • 1,203 citations

Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes

1997 • 987 citations

Biofilms, the customized microniche

1994 • 978 citations

Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes.

1994 • 964 citations

Expression of Pseudomonas aeruginosa Virulence Genes Requires Cell-to-Cell Communication

1993 • 854 citations

Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa

1997 • 852 citations

Quorum sensing by peptide pheromones and two‐component signal‐transduction systems in Gram‐positive bacteria

1997 • 773 citations

A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa.

1995 • 767 citations

Chromosomal genetics of Pseudomonas

1979 • 721 citations

A hierarchical quorum‐sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary‐phase sigma factor RpoS

1996 • 692 citations

Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and sequence of the region required for their replication in Pseudomonas aeruginosa

1994 • 569 citations

Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa.

1995 • 557 citations

Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family

1995 • 550 citations

Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa.

1995 • 525 citations

The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N‐butyryl‐homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase

1997 • 429 citations

The Pseudomonas aeruginosa Quorum-Sensing Signal Molecule N -(3-Oxododecanoyl)- <scp>l</scp> -Homoserine Lactone Has Immunomodulatory Activity

1998 • 428 citations

LasR of Pseudomonas aeruginosa is a transcriptional activator of the alkaline protease gene (apr) and an enhancer of exotoxin A expression

1993 • 359 citations

An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa

1995 • 344 citations

Effect of rpoS Mutation on the Stress Response and Expression of Virulence Factors in Pseudomonas aeruginosa

1999 • 343 citations

Vfr controls quorum sensing in Pseudomonas aeruginosa

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Construction of broad-host-range plasmid vectors for easy visible selection and analysis of promoters

1990 • 284 citations

Genetics of Pseudomonas

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Effects of molecular oxygen on detection of superoxide radical with nitroblue tetrazolium and on activity stains for catalase

1984 • 259 citations

Response of Pseudomonas aeruginosa to pyocyanin: mechanisms of resistance, antioxidant defenses, and demonstration of a manganese-cofactored superoxide dismutase

1992 • 250 citations

Protective Role of Catalase in Pseudomonas aeruginosa Biofilm Resistance to Hydrogen Peroxide

1999 • 234 citations

Sensing Starvation: a Homoserine Lactone—Dependent Signaling Pathway in Escherichia coli

1994 • 215 citations

Coordinate regulation of siderophore and exotoxin A production: molecular cloning and sequencing of the Pseudomonas aeruginosa fur gene

1993 • 213 citations

Effect of flow regime on the architecture of a Pseudomonas fluorescens biofilm

2002 • 205 citations

Roles of Pseudomonas aeruginosa las and rhl Quorum-Sensing Systems in Control of Twitching Motility

1999 • 189 citations

Characterization of the Erwinia chrysanthemi expI–expR locus directing the synthesis of two N‐acyl‐homoserine lactone signal molecules

1998 • 185 citations

A double staining method for differentiating between two classes of mycobacterial catalase in polyacrylamide electrophoresis gels

1986 • 173 citations

Pseudomonas aeruginosa sodA and sodB mutants defective in manganese- and iron-cofactored superoxide dismutase activity demonstrate the importance of the iron-cofactored form in aerobic metabolism

1995 • 171 citations

Quorum-sensing in Gram-negative bacteria

2001 • 170 citations

Spatial Patterns of Alkaline Phosphatase Expression within Bacterial Colonies and Biofilms in Response to Phosphate Starvation

1998 • 167 citations

Pseudomonas aeruginosa and cystic fibrosis: unusual bacterial adaptation and pathogenesis.

1986 • 166 citations

Cloning and characterization of the katB gene of Pseudomonas aeruginosa encoding a hydrogen peroxide-inducible catalase: purification of KatB, cellular localization, and demonstration that it is essential for optimal resistance to hydrogen peroxide

1995 • 165 citations

Functional analysis of the Pseudomonas aeruginosa autoinducer PAI

1996 • 157 citations

Ferric uptake regulator (Fur) mutants of Pseudomonas aeruginosa demonstrate defective siderophore-mediated iron uptake, altered aerobic growth, and decreased superoxide dismutase and catalase activities

1996 • 154 citations

Bacterioferritin A Modulates Catalase A (KatA) Activity and Resistance to Hydrogen Peroxide in Pseudomonas aeruginosa

1999 • 148 citations

Regulation of the xcp secretion pathway by multiple quorum‐sensing modulons in Pseudomonas aeruginosa

1997 • 133 citations

In vivo studies disprove an obligatory role of azurin in denitrification in Pseudomonas aeruginosa and show that azu expression is under control of RpoS and ANR

1997 • 125 citations

Starvation Selection Restores Elastase and Rhamnolipid Production in a Pseudomonas aeruginosa Quorum-Sensing Mutant

1998 • 117 citations

Bacteriocuprein superoxide dismutases in pseudomonads

1985 • 115 citations

Genetics of Pseudomonas.

1969 • 113 citations

Integration of the quorum‐sensing system in the regulatory networks controlling virulence factor synthesis in Erwinia chrysanthemi

1998 • 107 citations

An operon containing fumC and sodA encoding fumarase C and manganese superoxide dismutase is controlled by the ferric uptake regulator in Pseudomonas aeruginosa: fur mutants produce elevated alginate levels

1997 • 102 citations

Cloning and characterization of the Pseudomonas aeruginosa sodA and sodB genes encoding manganese- and iron-cofactored superoxide dismutase: demonstration of increased manganese superoxide dismutase activity in alginate-producing bacteria

1993 • 100 citations

In vitro biosynthesis of the Pseudomonas aeruginosa quorum‐sensing signal molecule N‐butanoyl‐<scp>L</scp>‐homoserine lactone

1998 • 85 citations

Two plasmids, X1918 and Z1918, for easy recovery of the xylE and lacZ reporter genes

1993 • 65 citations

Fumarase C activity is elevated in response to iron deprivation and in mucoid, alginate-producing Pseudomonas aeruginosa: cloning and characterization of fumC and purification of native fumC

1997 • 61 citations

[44] Pseudomonas aeruginosa biofilm sensitivity to biocides: Use of hydrogen peroxide as model antimicrobial agent for examining resistance mechanisms

1999 • 56 citations

Improved broad-host-range lac-based plasmid vectors for the isolation and characterization of protein fusions in Pseudomonas aeruginosa

1991 • 55 citations

Pseudomonas aeruginosa mutants altered in their sensitivity to the effect of iron on toxin A or elastase yields

1982 • 48 citations

Extracellular Signal Molecule(s) Involved in the Carbon Starvation Response of Marine Vibrio sp. Strain S14

1998 • 48 citations

Global analysis of the carbon starvation response of a marine Vibrio species with disruptions in genes homologous to relA and spoT

1996 • 34 citations