Ontogeny of thyroid hormone receptors and c-erbA expression during brown adipose tissue development: evidence of fetal acquisition of the mature thyroid status.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Identification of a tHyroid Hormone Receptor That Is Pituitary-Specific

1989 • 493 citations

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

1989 • 437 citations

Identification of a Novel Thyroid Hormone Receptor Expressed in the Mammalian Central Nervous System

1987 • 429 citations

Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue.

1987 • 345 citations

Alternative splicing generates messages encoding rat c-erbA proteins that do not bind thyroid hormone.

1988 • 300 citations

Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats.

1990 • 298 citations

Identification of a Rat c-erbAα-Related Protein Which Binds Deoxyribonucleic Acid but does not Bind Thyroid Hormone

1988 • 254 citations

Differential expression of alpha and beta thyroid hormone receptor genes in rat brain and pituitary.

1989 • 251 citations

Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein.

1985 • 241 citations

Isolation and characterization of rat cDNA clones for two distinct thyroid hormone receptors.

1988 • 237 citations

Triiodothyronine amplifies norepinephrine stimulation of uncoupling protein gene transcription by a mechanism not requiring protein synthesis.

1988 • 209 citations

Alpha- and beta-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture.

1990 • 204 citations

The Early Ontogenesis of Thyroid Hormone Receptor in the Rat Fetus*

1985 • 177 citations

Binding of 3,5,3′-Triiodothyronine (T₃) and its Analogs to thein VitroTranslational Products of c-erbA Protooncogenes: Differences in the Affinity of the α- and β-Forms for the Acetic Acid Analog and Failure of the Human Testis and Kidney α-2 Products to Bind T₃

1990 • 148 citations

Optimal response of key enzymes and uncoupling protein to cold in BAT depends on local T3 generation

1987 • 110 citations

Nuclear 3,5,3′-Triiodothyronine (T₃) in Brown Adipose Tissue: Receptor Occupancy and Sources of T₃as Determined byin VivoTechniques*

1987 • 99 citations

Immunofluorescence localization of thyroid hormone receptor protein beta 1 and variant alpha 2 in selected tissues: cerebellar Purkinje cells as a model for beta 1 receptor-mediated developmental effects of thyroid hormone in brain.

1991 • 98 citations

Thyroid Hormones and 5’-Deiodinase in the Rat Fetus Late in Gestation: Effects of Maternal Hypothyroidism*

1991 • 93 citations

Ontogeny and perinatal modulation of gene expression in rat brown adipose tissue

1990 • 80 citations

Thyroid Hormone Receptors from Liver Nuclei: Characteristics of Receptor from Normal, Thyroidectomized, and Triiodothyronine-Treated Rats; Measurement of Occupied and Unoccupied Receptors, and Chromatin Binding of Receptors*

1978 • 65 citations

Development of Phodopus sungorus brown preadipocytes in primary cell culture: effect of an atypical beta-adrenergic agonist, insulin, and triiodothyronine on differentiation, mitochondrial development, and expression of the uncoupling protein UCP.

1991 • 61 citations

Direct assessment of brown adipose tissue as a site of systemic tri-iodothyronine production in the rat

1987 • 57 citations

Thyroid hormones and 5'-deiodinase in rat brown adipose tissue during fetal life

1989 • 49 citations

Tri-iodothyronine-induced increase in rat liver nuclear thyroid-hormone receptors associated with increased mitochondrial α-glycerophosphate dehydrogenase activity

1979 • 40 citations

Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver

1989 • 35 citations

Iodothyronine 5′-deiodinase activity in rat brown adipose tissue during development

1987 • 34 citations

Coordinate Expression of Functionally Distinct Thyroid Hormone Receptor α Isoforms during Neonatal Brain Development

1991 • 24 citations

Nuclear 3,5,3′-Triiodothyronine Receptor Occupancy, Phosphoenolpyruvate Carboxykinase (PEPck) Messenger Ribonucleic Acid Levels and PEPck Enzyme Activity in Rat Liver*

1987 • 19 citations

Evidence for a differential physiological modulation of brown fat iodothyronine 5′-deiodinase activity in the perinatal period

1988 • 16 citations

Ontogenesis of the High Affinity NADPH-Dependent Cytosolic 3,5,3′-Triiodo-L-Thyronine-Binding Protein in Rat

1991 • 13 citations

Pituitary nuclear triiodothyronine receptors during development in the rat

1983 • 9 citations