Transcriptional Profiling of Interferon Regulatory Factor 3 Target Genes: Direct Involvement in the Regulation of Interferon-Stimulated Genes

HOW CELLS RESPOND TO INTERFERONS

1998 • 3,937 citations

Antiviral Actions of Interferons

2001 • 2,683 citations

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

1998 • 1,781 citations

Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction

2000 • 1,304 citations

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

1998 • 1,040 citations

Viruses and Interferons

2001 • 985 citations

Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation

1998 • 901 citations

Functional classification of interferon-stimulated genes identified using microarrays

2001 • 882 citations

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300

1998 • 812 citations

Virus Infection Induces the Assembly of Coordinately Activated Transcription Factors on the IFN-β Enhancer In Vivo

1998 • 723 citations

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

1998 • 602 citations

Cellular gene expression altered by human cytomegalovirus: Global monitoring with oligonucleotide arrays

1998 • 445 citations

Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

1998 • 433 citations

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1995 • 342 citations

Interferon Regulatory Factor 3 and CREB-Binding Protein/p300 Are Subunits of Double-Stranded RNA-Activated Transcription Factor DRAF1

1998 • 334 citations

The Mechanism of Transcriptional Synergy of an In Vitro Assembled Interferon-β Enhanceosome

1997 • 333 citations

Structural and Functional Analysis of Interferon Regulatory Factor 3: Localization of the Transactivation and Autoinhibitory Domains

1999 • 319 citations

Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: Induction of interferon-responsive RNAs

1997 • 298 citations

Microarray Analysis Identifies Interferon-Inducible Genes and Stat-1 as Major Transcriptional Targets of Human Papillomavirus Type 31

2000 • 285 citations

Regulation of Type I Interferon Gene Expression by Interferon Regulatory Factor-3

1998 • 278 citations

Selective DNA Binding and Association with the CREB Binding Protein Coactivator Contribute to Differential Activation of Alpha/Beta Interferon Genes by Interferon Regulatory Factors 3 and 7

2000 • 274 citations

Essential Role of Interferon Regulatory Factor 3 in Direct Activation of RANTES Chemokine Transcription

1999 • 273 citations

Altered Cellular mRNA Levels in Human Cytomegalovirus-Infected Fibroblasts: Viral Block to the Accumulation of Antiviral mRNAs

2001 • 273 citations

Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3

1998 • 265 citations

Herpes Simplex Virus Triggers and Then Disarms a Host Antiviral Response

2001 • 263 citations

Involvement of the IRF family transcription factor IRF‐3 in virus‐induced activation of the IFN‐β gene

1998 • 262 citations

Quantitative Assessment of DNA Microarrays—Comparison with Northern Blot Analyses

2001 • 217 citations

Regulation of RANTES Chemokine Gene Expression Requires Cooperativity Between NF-κB and IFN-Regulatory Factor Transcription Factors

2000 • 215 citations

A new pathway of translational regulation mediated by eukaryotic initiation factor 3

2000 • 213 citations

A Comprehensive View of Regulation of Gene Expression by Double-stranded RNA-mediated Cell Signaling

2001 • 212 citations

Regulated Nuclear-Cytoplasmic Localization of Interferon Regulatory Factor 3, a Subunit of Double-Stranded RNA-Activated Factor 1

2000 • 206 citations

Identification of Distinct Signaling Pathways Leading to the Phosphorylation of Interferon Regulatory Factor 3

2001 • 193 citations

Gene Induction Pathways Mediated by Distinct IRFs during Viral Infection

2001 • 186 citations

Induction of the Human Protein P56 by Interferon, Double-Stranded RNA, or Virus Infection

2000 • 166 citations

The IRF-3 Transcription Factor Mediates Sendai Virus-Induced Apoptosis

2000 • 159 citations

Cytomegalovirus Activates Interferon Immediate-Early Response Gene Expression and an Interferon Regulatory Factor 3-Containing Interferon-Stimulated Response Element-Binding Complex

1998 • 158 citations

Global Analysis of Herpes Simplex Virus Type 1 Transcription Using an Oligonucleotide-Based DNA Microarray

2000 • 147 citations

Transcriptional Induction by Double-stranded RNA Is Mediated by Interferon-stimulated Response Elements without Activation of Interferon-stimulated Gene Factor 3

1995 • 139 citations

Activation of cellular interferon-responsive genes after infection of human cells with herpes simplex virus type 1

2000 • 132 citations

p38-dependent Activation of Interferon Regulatory Factor 3 by Lipopolysaccharide

1999 • 125 citations

Development of a Toxicological Gene Array and Quantitative Assessment of This Technology

2000 • 125 citations

New inducers revealed by the promoter sequence analysis of two interferon-activated human genes

1987 • 110 citations

Posttranslational Regulation of IRF-4 Activity by the Immunophilin FKBP52

2000 • 98 citations

Reconstitution of Virus-mediated Expression of Interferon α Genes in Human Fibroblast Cells by Ectopic Interferon Regulatory Factor-7

2000 • 98 citations

Characterization of Specific DNA-binding Factors Activated by Double-stranded RNA as Positive Regulators of Interferon α/β-stimulated Genes

1995 • 82 citations

Apoptosis is promoted by the dsRNA‐activated factor (DRAF1) during viral infection independent of the action of interferon or p53

2001 • 66 citations

Viral Activation of Interleukin-15 (IL-15): Characterization of a Virus-Inducible Element in the IL-15 Promoter Region

2000 • 63 citations

IFI60/ISG60/IFIT4, a New Member of the Human IFI54/IFIT2 Family of Interferon-Stimulated Genes

1998 • 59 citations

Novel functions of interferon-induced proteins

2000 • 58 citations

The IFI‐56K and IFI‐54K interferon‐inducible human genes belong to the same gene family

1988 • 32 citations

Binding of 125I-labeled human interferon to cell lines with low sensitivity to interferon.

1984 • 23 citations