Resistance to -Lactam Antibiotics in Bacteroides Spp.

A functional classification scheme for beta-lactamases and its correlation with molecular structure

1995 • 2,497 citations

The β-Lactamases of Gram-Negative Bacteria and their Possible Physiological Role

1973 • 719 citations

Susceptibility of Anaerobic Bacteria to 23 Antimicrobial Agents

1976 • 448 citations

Anaerobic Infections

1974 • 441 citations

Diffusion of beta-lactam antibiotics through the porin channels of Escherichia coli K-12

1985 • 338 citations

Anaerobic infections of the lung and pleural space.

1974 • 334 citations

Aerobic and Anaerobic Bacteria in Diabetic Foot Ulcers

1976 • 228 citations

Cloning and sequencing of the class B beta-lactamase gene (ccrA) from Bacteroides fragilis TAL3636

1990 • 173 citations

Beta-lactamase-mediated imipenem resistance in Bacteroides fragilis

1986 • 169 citations

Sequencing the gene for an imipenem-cefoxitin-hydrolyzing enzyme (CfiA) from Bacteroides fragilis TAL2480 reveals strong similarity between CfiA and Bacillus cereus beta-lactamase II

1990 • 164 citations

Anaerobic infections of the female genital tract: Bacteriologic and therapeutic aspects

1973 • 155 citations

Bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazole.

1977 • 149 citations

Insertion of a novel DNA sequence, IS 1186, upstream of the silent carbapenemase gene cfiA, promotes expression of carbapenem resistance in clinical isolates of Bacteroides fragilis

1994 • 148 citations

Anaerobic infections in humans: an overview

1995 • 147 citations

Genetic and biochemical analysis of a novel Ambler class A beta-lactamase responsible for cefoxitin resistance in Bacteroides species

1993 • 142 citations

Mode of action of azthreonam

1982 • 128 citations

In vitro antibacterial activity of SM-7338, a carbapenem antibiotic with stability to dehydropeptidase I

1989 • 116 citations

Genotypic identification of two groups within the species Bacteroides fragilis by ribotyping and by analysis of PCR-generated fragment patterns and insertion sequence content

1995 • 115 citations

Properties of novel beta-lactamase produced by Bacteroides fragilis

1983 • 113 citations

Modification of penicillin-binding proteins as mechanisms of beta-lactam resistance

1986 • 109 citations

Cloning and characterization of the endogenous cephalosporinase gene, cepA, from Bacteroides fragilis reveals a new subgroup of Ambler class A beta-lactamases

1993 • 96 citations

Comparative In Vitro Activity of New Beta-Lactam Antibiotics Against Anaerobic Bacteria

1981 • 95 citations

Formation of Beta-Lactamase in Bacteroides fragilis : Cell-Bound and Extracellular Activity

1976 • 94 citations

Biochemical characterization of the metallo-beta-lactamase CcrA from Bacteroides fragilis TAL3636

1992 • 88 citations

A silent carbapenemase gene in strains of Bacteroides fragilis can be expressed after a one-step mutation

1992 • 81 citations

Conjugal transfer of imipenem resistance in Bacteroides fragilis.

1992 • 76 citations

Sensitivity of Four Species of Bacteroides to Antibiotics

1955 • 75 citations

Cefoxitin inactivation by Bacteroides fragilis

1983 • 72 citations

In vitro activity of N-formimidoyl thienamycin, moxalactam, and other new beta-lactam agents against Bacteroides fragilis: contribution of beta-lactamase to resistance

1981 • 68 citations

Insertional activation of cepA leads to high-level beta-lactamase expression in Bacteroides fragilis clinical isolates

1994 • 67 citations

Antimicrobial resistance in Bacteroides

1987 • 66 citations

Antibiotic sensitivity of theBacteroides fragilis group in Europe

1992 • 64 citations

Characterisation of a -Lactamase Obtained from a Strain of Bacteroides Fragilis Resistant to -Lactam Antibiotics

1973 • 62 citations

Isolation and characterization of outer membranes of Bacteroides thetaiotaomicron grown on different carbohydrates

1984 • 60 citations

Factors Contributing to Resistance to Beta-Lactam Antibiotics in Bacteroides fragilis

1979 • 59 citations

Cefoxitin resistance in Bacteroides species: evidence indicating two mechanisms causing decreased susceptibility

1987 • 57 citations

Epidemiology of the Bacteroides fragilis group in the colonic flora in 10 patients with colonic cancer

1989 • 57 citations

The antimicrobial susceptibility patterns of the Barteroides fragilis group in the United States, 1987

1990 • 55 citations

Alterations to the penicillin-binding proteins in the Bacteroides fragilis group: a mechanism for non-β-lactamase mediated cefoxitin resistance

1990 • 55 citations

Molecular and genetic analysis of the Bacteroides uniformis cephalosporinase gene, cblA, encoding the species-specific beta-lactamase

1994 • 55 citations

Simultaneous resistance to metronidazole, co-amoxiclav, and imipenem in clinical isolate of Bacteroides fragilis

1995 • 52 citations

Activity of cefoperazone and two beta-lactamase inhibitors, sulbactam and clavulanic acid, against Bacteroides spp. correlated with beta-lactamase production

1982 • 51 citations

Biochemical properties and purification of metallo-beta-lactamase from Bacteroides fragilis

1991 • 50 citations

Comparative activities of newer beta-lactam agents against members of the Bacteroides fragilis group

1990 • 49 citations

Resistance to β-Lactam Antibiotics in Anaerobic Bacteria

1990 • 48 citations

Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis

1988 • 47 citations

Contribution of enzymatic properties, cell permeability, and enzyme expression to microbiological activities of beta-lactams in three Bacteroides fragilis isolates that harbor a metallo-beta-lactamase gene

1994 • 41 citations

Purification and properties of beta-lactamase from Bacteroides fragilis

1978 • 39 citations

Comparative susceptibility of the Bacteroides fragilis group species and other anaerobic bacteria to meropenem, imipenem, piperacillin, cefoxitin, ampicillin/sulbactam, clindamycin and metronidazole

1993 • 39 citations

Characterization of three different beta-lactamases from the Bacteroides fragilis group

1980 • 37 citations

Escherichia coli chromosomal mutations that permit direct cloning of the Bacteroides fragiiis metallo‐β‐lactamase gene, ccrA

1991 • 37 citations

Beta-lactamase production and susceptibility of US and European anaerobic gram-negative bacilli to beta-lactams and other agents

1992 • 37 citations

The β-lactamases of Bacteroides species

1981 • 36 citations

An investigation of -lactamases from clinical isolates of Bacteroides species

1992 • 36 citations

Properties of the penicillin-binding proteins of four species of the genus Bacteroides

1986 • 34 citations

Susceptibilities of species of the Bacteroides fragilis group to 10 antimicrobial agents

1990 • 33 citations

Anaerobes in Mixed Infections

1981 • 32 citations

Purification and characterization of an imipenem hydrolysing metallo-β-lactamase from Bacteroides fragilis

1992 • 30 citations

Antibacterial activity of new β-lactam antibiotics on cefoxitin-resistant strains of Baeteroides fragilis

1980 • 29 citations

Characterization of β-lactamases in clinical isolates of Bacteroides

1986 • 27 citations

The effect of lipopolysaccharide on lipid bilayer permeability of β‐lactam antibiotics

1984 • 26 citations

Penicillin-binding proteins in Bacteroides fragilis.

1983 • 24 citations

The .BETA.-lactamases of genus Bacteroides.

1983 • 22 citations

Transferable resistance to cefoxitin in Bacteroides thetaiotaomicron

1982 • 22 citations

Permeability to β-lactams in Bacteroides fragilis

1988 • 22 citations

In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes

1994 • 21 citations

Mechanisms responsible for reduced susceptibility to imipenem in Bacteroides fragilis

1996 • 21 citations

Changes in the susceptibility ofBacteroides fragilis group organisms to various antimicrobial agents 1979–1989

1992 • 20 citations

Purification and characterization of a new beta-lactamase from Bacteroides uniformis

1995 • 19 citations

In-vitro activity of cefoperazone-sulbactam against Bacteroides species

1986 • 18 citations

The isolation and characterization of a porin protein fromBacteroides fragilis

1996 • 14 citations

Identification of three porins in the outer membrane ofBacteroides fragilis

1995 • 14 citations

The role of β-lactamase and the permeability barrier on the activity of cephalosporins against members of the Bacteroides fragilis group

1987 • 12 citations

Comparative in–vitro activity of temocillin (BRL 17421), a new penicillin

1983 • 12 citations

β-Lactamase produced by a highly β-lactam-resistant strain of Barteroides fragilis: an obstacle to the chemotherapy of experimental mixed infections

1991 • 9 citations

Penicillin-binding proteins in Bacteroides fragilis and their affinities for several new cephalosporins

1983 • 8 citations

Outer membrane proteins of thebacteroides fragilis group

1981 • 8 citations

In-vitro susceptibility of the Bacteroides fragilis group and the inoculum effect of newer β-lactam antibiotics on this group of organisms

1989 • 7 citations

Potential Factors Influencing Carbapenem Activity Against Bacteroides fragilis Group Isolates

1995 • 2 citations