Sir2-Dependent Activation of Acetyl-CoA Synthetase by Deacetylation of Active Lysine

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

2001 • 1,892 citations

Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae

2000 • 1,756 citations

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

2002 • 1,051 citations

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

1997 • 678 citations

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability.

1995 • 601 citations

ACYL ADENYLATES: AN ENZYMATIC MECHANISM OF ACETATE ACTIVATION

1956 • 355 citations

Manipulation of a Nuclear NAD+ Salvage Pathway Delays Aging without Altering Steady-state NAD+ Levels

2002 • 289 citations

The Interaction of Alba, a Conserved Archaeal Chromatin Protein, with Sir2 and Its Regulation by Acetylation

2002 • 278 citations

Enzymatic activities of Sir2 and chromatin silencing

2001 • 158 citations

The Role of Lysine 529, a Conserved Residue of the Acyl-Adenylate-Forming Enzyme Superfamily, in Firefly Luciferase

2000 • 112 citations

Characterization of the Propionyl-CoA Synthetase (PrpE) Enzyme of Salmonella enterica: Residue Lys592 Is Required for Propionyl-AMP Synthesis

2002 • 110 citations

The prpE gene of Salmonella typhimurium LT2 encodes propionyl-CoA synthetase

1999 • 76 citations

cobB function is required for catabolism of propionate in Salmonella typhimurium LT2: evidence for existence of a substitute function for CobB within the 1,2-propanediol utilization (pdu) operon

1996 • 21 citations

Identification of a lysine residue at a nucleotide binding site in the firefly luciferase with p-fluorosulfonyl[14C]benzoyl-5'-adenosine

1981 • 14 citations