Synthetic peptides as antagonists of the anaphylatoxin C3a

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Improved silver staining procedure for fast staining in PhastSystem Development Unit. I. Staining of sodium dodecyl sulfate gels

1988 • 697 citations

Anaphylatoxin inactivator of human plasma: its isolation and characterization as a carboxypeptidase

1970 • 509 citations

Conformational restrictions of biologically active peptides via amino acid side chain groups

1982 • 395 citations

Inflammation: Basic Principles and Clinical Correlates

1988 • 275 citations

Effects of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates.

1986 • 267 citations

Endotoxin-induced shock in the rat. A role for C5a.

1989 • 182 citations

Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a.

1990 • 160 citations

Role of Complement Activation in a Model of Adult Respiratory Distress Syndrome

1980 • 154 citations

Structure and Function of C3a Anaphylatoxin*

1990 • 151 citations

Substituted 4,6-diaminoquinolines as inhibitors of C5a receptor binding

1992 • 84 citations

The active site of C3a anaphylatoxin.

1980 • 82 citations

Demonstration of a specific C3a receptor on guinea pig platelets.

1988 • 73 citations

9-(2-Sulfo)fluorenylmethyloxycarbonyl chloride, a new reagent for the purification of synthetic peptides

1978 • 73 citations

Elevated C3 anaphylatoxin levels in synovial fluids from patients with rheumatoid arthritis

1985 • 68 citations

Characterization of C3a receptor‐proteins on guinea pig platelets and human polymorphonuclear leukocytes

1989 • 56 citations

Degradation of human anaphylatoxin C3a by rat peritoneal mast cells: a role for the secretory granule enzyme chymase and heparin proteoglycan.

1986 • 47 citations

Guinea Pigs Deficient in C2, C4, C3 or the C3a Receptor

1987 • 42 citations

Peptide Analogues of the Anaphylatoxin C3a; Syntheses and Properties

1989 • 38 citations

Platelet Activation: a New Biological Activity of Guinea‐pig C3a Anaphylatoxin

1978 • 37 citations

Design and biological activity of a new generation of synthetic C3a analogues by combination of peptidic and non-peptidic elements.

1988 • 26 citations

A critical interpretation of experiments of binding of peptide hormone to specific receptors by computer modelling

1982 • 24 citations

Reevaluation of the C3a active site using short synthetic C3a analogues

1990 • 23 citations

In vivo effects of C3a on neutrophils and its contribution to inflammatory lung processes in a guinea-pig model.

1988 • 22 citations

Human C5a Anaphylatoxin: Gene Cloning and Expression in Escherichia coli

1992 • 21 citations

Characterization of the C5a Receptor on Guinea Pig Platelets

1991 • 18 citations

Low zone desensitization: a stimulus-specific control mechanism of cell response. Investigations on anaphylatoxin-induced platelet secretion.

1982 • 14 citations

Functional activities of synthetic anaphylatoxic peptides in widely used biological assays

1992 • 11 citations

Synthetic C3a analogs as specific inhibitors of C3a activity

1981 • 11 citations

Synthesis and properties of C-terminal C3A-analogues with methyleneamino bonds

1991 • 1 citations