Functional Implications of the Subunit Composition of Neuronal CaM Kinase II

Synaptic plasticity: LTP and LTD

1994 • 1,301 citations

Sensitivity of CaM Kinase II to the Frequency of Ca ²⁺ Oscillations

1998 • 1,263 citations

Autophosphorylation at Thr ²⁸⁶ of the α Calcium-Calmodulin Kinase II in LTP and Learning

1998 • 1,045 citations

NEURONAL Ca²⁺/CALMODULIN-DEPENDENT PROTEIN KINASES

1992 • 713 citations

Dynamic Control of CaMKII Translocation and Localization in Hippocampal Neurons by NMDA Receptor Stimulation

1999 • 652 citations

Calmodulin Trapping by Calcium-Calmodulin-Dependent Protein Kinase

1992 • 644 citations

CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP

1995 • 530 citations

Dual role of calmodulin in autophosphorylation of multifunctional cam kinase may underlie decoding of calcium signals

1994 • 508 citations

Purification and characterization of smooth muscle myosin light chain kinase.

1981 • 501 citations

Purification and characterization of a calmodulin-dependent protein kinase that is highly concentrated in brain.

1983 • 481 citations

Autophosphorylation-dependent Targeting of Calcium/ Calmodulin-dependent Protein Kinase II by the NR2B Subunit of theN-Methyl-d-aspartate Receptor

1998 • 442 citations

Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs

1989 • 397 citations

Calcium/calmodulin-dependent protein kinase II is associated with the N -methyl- <scp>d</scp> -aspartate receptor

1999 • 377 citations

CaMKIIβ Functions As an F-Actin Targeting Module that Localizes CaMKIIα/β Heterooligomers to Dendritic Spines

1998 • 336 citations

Distinct forebrain and cerebellar isozymes of type II Ca2+/calmodulin-dependent protein kinase associate differently with the postsynaptic density fraction.

1985 • 305 citations

Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulation

1989 • 293 citations

Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase.

1987 • 287 citations

Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2+-independent activity

1988 • 283 citations

Deduced primary structure of the beta subunit of brain type II Ca2+/calmodulin-dependent protein kinase determined by molecular cloning.

1987 • 253 citations

Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus.

1994 • 251 citations

Visualization of the Distribution of Autophosphorylated Calcium/Calmodulin-Dependent Protein Kinase II after Tetanic Stimulation in the CA1 Area of the Hippocampus

1997 • 234 citations

Structural features of Ca2+/calmodulin-dependent protein kinase II revealed by electron microscopy.

1991 • 227 citations

Inhibitory autophosphorylation of multifunctional Ca2+/calmodulin-dependent protein kinase analyzed by site-directed mutagenesis.

1992 • 220 citations

Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase.

1984 • 213 citations

Activation of the multifunctional Ca2+/calmodulin-dependent protein kinase by autophosphorylation: ATP modulates production of an autonomous enzyme.

1986 • 207 citations

Abnormal Hippocampal Spatial Representations in αCaMKII ^T286A and CREB ^αΔ− Mice

1998 • 186 citations

Spatial and temporal changes in signal transduction pathways during LTP

1994 • 184 citations

Multifunctional Ca2+/calmodulin-dependent protein kinase is necessary for nuclear envelope breakdown.

1990 • 173 citations

Developmental and regional expression of multifunctional Ca2+/calmodulin-dependent protein kinase isoforms in rat brain

1995 • 164 citations

Substrate-directed Function of Calmodulin in Autophosphorylation of Ca2+/Calmodulin-dependent Protein Kinase II

1998 • 163 citations

Mechanism of autophosphorylation of the multifunctional Ca2+/calmodulin-dependent protein kinase.

1985 • 153 citations

Molecular cloning of the cDNA encoding the third polypeptide (gamma) of brain calmodulin-dependent protein kinase II.

1988 • 148 citations

Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism

1993 • 141 citations

alpha KAP is an anchoring protein for a novel CaM kinase II isoform in skeletal muscle

1998 • 135 citations

Decoding calcium signals by multifunctional CaM kinase

1992 • 131 citations

Regulation of Ca2+/calmodulin-dependent protein kinase II by inter- and intrasubunit-catalyzed autophosphorylations.

1994 • 117 citations

Ca2+-regulated Dynamic Compartmentalization of Calmodulin in Living Smooth Muscle Cells

1995 • 106 citations

Cloning and analysis of two new isoforms of multifunctional Ca2+/calmodulin-dependent protein kinase. Expression in multiple human tissues.

1993 • 92 citations

Expression and characterization of calmodulin-dependent protein kinase II from cloned cDNAs in Chinese hamster ovary cells

1989 • 86 citations

Calmodulin Binds to Specific Sequences in the Cytoplasmic Domain of C-CAM and Down-regulates C-CAM Self-association

1996 • 72 citations

Identification of Domains Essential for the Assembly of Calcium/Calmodulin-dependent Protein Kinase II Holoenzymes

1998 • 71 citations

A Mechanism for Calmodulin (CaM) Trapping by CaM-kinase II Defined by a Family of CaM-binding Peptides

1998 • 71 citations

Identification of novel human tumor cell-specific CaMK-II variants

1997 • 70 citations

Dendritic localization of type II calcium calmodulin-dependent protein kinase mRNA in normal and reinnervated rat hippocampus

1992 • 58 citations

Structure, expression, and chromosome location of the gene for the beta subunit of brain-specific Ca2+/calmodulin-dependent protein kinase II identified by transgene integration in an embryonic lethal mouse mutant.

1992 • 57 citations

GAP-43 as a ‘calmodulin sponge’ and some implications for calcium signalling in axon terminals

1990 • 55 citations

Nitric oxide synthase expression in single hippocampal neurons

1994 • 31 citations

Proteolytic activation of calcium/calmodulin-dependent protein kinase II: Putative function in synaptic plasticity

1990 • 31 citations

The unique properties of glutamate receptor channels

1993 • 29 citations

Functional Diversity of Alternatively Spliced Isoforms of Drosophila Ca2+/Calmodulin-dependent Protein Kinase II

1996 • 24 citations

Functional Heterogeneity of Alternatively Spliced Isoforms of Drosophila Ca²⁺/Calmodulin‐Dependent Protein Kinase II

1996 • 22 citations

Subcellular distribution of α, and β subunit proteins of Ca²⁺ /calmodulin‐dependent protein kinase II expressed in Chinese hamster ovary cells

1990 • 12 citations

Purification and characterization of the Ca2+/calmodulin-dependent protein kinase II from chicken forebrain

1994 • 7 citations