Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

Identification and characterization of the familial adenomatous polyposis coli gene

1991 • 2,806 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

1991 • 1,890 citations

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

1986 • 1,863 citations

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

1990 • 1,080 citations

Identification of deletion mutations and three new genes at the familial polyposis locus

1991 • 769 citations

UPPER GASTROINTESTINAL CANCER IN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS

1989 • 763 citations

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1991 • 758 citations

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

1992 • 562 citations

Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer.

1990 • 511 citations

A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells.

1985 • 320 citations

Hereditary Gastrointestinal Polyposis Syndromes

1986 • 268 citations