Cotranslational Ubiquitination of Cystic Fibrosis Transmembrane Conductance Regulator in Vitro

Molecular chaperones in cellular protein folding

1996 • 3,540 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

UBIQUITIN-DEPENDENT PROTEIN DEGRADATION

1996 • 1,680 citations

A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein

1989 • 1,463 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

Degradation of CFTR by the ubiquitin-proteasome pathway

1995 • 1,285 citations

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

1995 • 885 citations

A 26 S protease subunit that binds ubiquitin conjugates.

1994 • 759 citations

Quality control in the secretory pathway

1995 • 679 citations

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1994 • 651 citations

THE UBIQUITIN-CONJUGATION SYSTEM

1992 • 561 citations

ER Quality Control: The Cytoplasmic Connection

1997 • 528 citations

Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins.

1994 • 482 citations

Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

1997 • 451 citations

The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

1993 • 375 citations

Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.

1994 • 359 citations

The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment.

1993 • 335 citations

The Cotranslational Integration of Membrane Proteins into the Phospholipid Bilayer Is a Multistep Process

1996 • 246 citations

Hemin inhibits ATP-dependent ubiquitin-dependent proteolysis: role of hemin in regulating ubiquitin conjugate degradation.

1981 • 141 citations

Aurintricarboxylic Acid: Inhibitor of Initiation of Protein Synthesis

1971 • 118 citations

Differential Effects of Ubiquitin Aldehyde on Ubiquitin and ATP-Dependent Protein Degradation

1996 • 32 citations