Intracellular pH and its relationship to regulation of ion transport in normal and cystic fibrosis human nasal epithelia.

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

2013 • 2,504 citations

Intracellular pH.

1981 • 2,440 citations

Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.

1986 • 561 citations

Generation of cAMP-Activated Chloride Currents by Expression of CFTR

1991 • 550 citations

Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

1991 • 508 citations

Abnormal Ion Permeation Through Cystic Fibrosis Respiratory Epithelium

1983 • 493 citations

Homocellular regulatory mechanisms in sodium-transporting epithelia: avoidance of extinction by “flush-through”

1981 • 273 citations

Lowering of pHi inhibits Ca2+-activated K+ channels in pancreatic B-cells

1984 • 262 citations

A hypothesis for pulmonary clearance and its implications.

1968 • 211 citations

Abnormal apical cell membrane in cystic fibrosis respiratory epithelium. An in vitro electrophysiologic analysis.

1987 • 153 citations

Intracellular Cl- activity and cellular Cl- pathways in cultured human airway epithelium

1989 • 150 citations

Activation of an apical Cl- conductance by Ca2+ ionophores in cystic fibrosis airway epithelia

1989 • 139 citations

Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy.

1988 • 128 citations

Increased Cytosolic pH in Multidrug-Resistant Human Lung Tumor Cells: Effect of Verapamil

1989 • 120 citations

Intracellular pH controls cell membrane Na+ and K+ conductances and transport in frog skin epithelium.

1988 • 111 citations

Culture of human nasal epithelial cells on collagen matrix supports. A comparison of bioelectric properties of normal and cystic fibrosis epithelia.

1985 • 109 citations

Sodium Transport Inhibition by Amiloride Reduces Basolateral Membrane Potassium Conductance in Tight Epithelia

1982 • 103 citations

Role of Na+/H+ exchange in the control of intracellular pH and cell membrane conductances in frog skin epithelium.

1988 • 85 citations

Cellular Cl- transport in cultured cystic fibrosis airway epithelium

1989 • 75 citations

Shunt resistance and ion permeabilities in normal and cystic fibrosis airway epithelia

1989 • 73 citations

Transcellular cross-talk between epithelial cell membranes

1982 • 73 citations

Extra- and intracellular hydrogen ion-selective microelectrode based on neutral carriers with extended pH response range in acid media

1988 • 72 citations

Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells

1990 • 72 citations

Transcellular sodium transport in cultured cystic fibrosis human nasal epithelium

1991 • 72 citations

Abnormal Respiratory Epithelial Ion Transport in Cystic Fibrosis

1986 • 67 citations

Characterization of potassium channels in respiratory cells

1989 • 49 citations

Characterization of potassium channels in respiratory cells

1989 • 46 citations

Potassium transport by flounder intestinal mucosa

1984 • 46 citations

Interactions of pH and K+ conductance in cultured bovine retinal pigment epithelial cells

1986 • 34 citations

Reconstitution in phospholipid vesicles of calcium-activated potassium channel from outer renal medulla

1987 • 32 citations

The Ca2+-sensitive K+-conductance of the human red cell membrane is strongly dependent on cellular pH

1985 • 31 citations

Sodium-proton exchange across the apical membrane of the alveolar type II cell of the fetal sheep

1990 • 24 citations

Regulation of Na⁺/H⁺ Exchange in Lymphocytes^a

1985 • 24 citations

Epithelial pH and Ion Transport Regulation by Proton Pumps and Exchangers

2007 • 22 citations

Intracellular pH and membrane potassium conductance in rabbit distal colon

1990 • 18 citations

The Na+/H+ antiporter in rat alveolar type II cells and its role in stimulated surfactant secretion

1988 • 15 citations