Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells (HL-60).

A procedure for the isolation of deoxyribonucleic acid from micro-organisms

1961 • 11,554 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Cellular differentiation, cytidine analogs and DNA methylation

1980 • 1,803 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

5-Methylcytosine in Eukaryotic DNA

1981 • 744 citations

Reactivation of an Inactive Human X Chromosome: Evidence for X Inactivation by DNA Methylation

1981 • 711 citations

Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine.

1982 • 575 citations

DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells

1981 • 464 citations

Methylation and gene control

1982 • 210 citations

Biological Effects of 5-Azacytidine in Eukaryotes

1974 • 198 citations

DNA Methylation--A Regulatory Signal in Eukaryotic Gene Expression

1981 • 192 citations

Studies of X chromosome DNA methylation in normal human cells

1982 • 157 citations

Hypomethylation of DNA during differentiation of friend erythroleukemia cells

1980 • 154 citations

Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides

1978 • 150 citations

5-Azacytidine-Induced Reactivation of a Herpes Simplex Thymidine Kinase Gene

1982 • 144 citations

Induction of Differentiation of Human Promyelocytic Leukemia Cells (HL-60) by Nucleosides and Methotrexate

1981 • 120 citations

Kinetics and Mechanisms of Degradation of the Antileukemic Agent 5‐Azacytidine in Aqueous Solutions

1975 • 113 citations

A SIMPLE AND RAPID METHOD FOR THE ISOLATION OF ENZYMATICALLY ACTIVE HELA CELL NUCLEI

1969 • 101 citations

5-Azacytidine induction of mouse endogenous type C virus and suppression of DNA methylation.

1981 • 99 citations

Incorporation of 5-Azacytidine into nucleic acids of Escherichia coli

1968 • 69 citations

The inhibition of DNA(cytosine-5)methylases by 5-azacytidine. The effect of azacytosine-containing DNA.

1981 • 66 citations

Mechanism of 5-azacytidine-induced transfer RNA cytosine-5-methyltransferase deficiency.

1980 • 51 citations

Functionally deficient differentiation of HL-60 promyelocytic leukemia cells induced by phorbol myristate acetate.

1981 • 46 citations

Effect of maturation on the response of human promyelocytic leukemia cells (HL-60) to the tumor promoter 12-o-tetradecanolyphorbol-13-acetate.

1980 • 37 citations

5-Azacytidine—A New Anticancer Drug with Significant Activity in Acute Myeloblastic Leukemia

1977 • 30 citations

Catabolism of 2-deoxyglucose by phagocytic leukocytes in the presence of 12-O-tetradecanoyl phorbol-13-acetate.

1978 • 28 citations

L-Ethionine as an inducer of differentiation in human promyelocytic leukemia cells (HL-60).

1980 • 27 citations

Mechanism of inhibition of DNA methyltransferase by 5-azacytosine substituted DNA

1982 • 3 citations