Functional Properties of Motoneurons Derived from Mouse Embryonic Stem Cells

Handbook of Physiology.

1960 • 10,428 citations

Single-Channel Recording

1995 • 2,565 citations

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

2001 • 1,874 citations

Directed Differentiation of Embryonic Stem Cells into Motor Neurons

2002 • 1,723 citations

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease

2002 • 1,622 citations

Induction of Midbrain Dopaminergic Neurons from ES Cells by Stromal Cell–Derived Inducing Activity

2000 • 1,267 citations

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells

2000 • 1,262 citations

Embryonic Stem Cells Express Neuronal Properties in Vitro

1995 • 1,173 citations

Neural progenitors from human embryonic stem cells

2001 • 1,113 citations

A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube

2000 • 1,077 citations

Requirement for the Homeobox Gene Hb9 in the Consolidation of Motor Neuron Identity

1999 • 605 citations

The hyperpolarization of spinal motoneurones by glycine and related amino acids

1968 • 481 citations

Serotonin‐induced bistability of turtle motoneurones caused by a nifedipine‐sensitive calcium plateau potential.

1989 • 465 citations

Inhibitory of glycine on spinal neurons in the cat.

1968 • 411 citations

Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons

1995 • 361 citations

Active Suppression of Interneuron Programs within Developing Motor Neurons Revealed by Analysis of Homeodomain Factor HB9

1999 • 350 citations

Differential subcellular localization of tubulin and the microtubule- associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies

1984 • 346 citations

A Requirement for Retinoic Acid-Mediated Transcriptional Activation in Ventral Neural Patterning and Motor Neuron Specification

2003 • 340 citations

Expression of the KCl cotransporter KCC2 parallels neuronal maturation and the emergence of low intracellular chloride

2003 • 304 citations

Quantitative aspects of repetitive firing of mammalian motoneurones, caused by injected currents

1963 • 288 citations

Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles

1996 • 283 citations

Mixed‐agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.

1984 • 274 citations

Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells

2003 • 270 citations

Hyperexcitable dendrites in motoneurons and their neuromodulatory control during motor behavior

2003 • 244 citations

Early development of glycine- and GABA-mediated synapses in rat spinal cord

1992 • 234 citations

Dendritic L‐type calcium currents in mouse spinal motoneurons: implications for bistability

2000 • 234 citations

Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats

2004 • 232 citations

Development of Ionic Currents Underlying Changes in Action Potential Waveforms in Rat Spinal Motoneurons

1998 • 192 citations

Relation between isometric force and stimulus rate in cat's hindlimb motor units of different twitch contraction time

1983 • 188 citations

On the regulation of repetitive firing in lumbar motoneurones during fictive locomotion in the cat

1992 • 158 citations

Membrane currents in visually identified motoneurones of neonatal rat spinal cord.

1990 • 157 citations

The regulation of synaptogenesis during normal development and following activity blockade

1991 • 149 citations

Optimal motor patterns for activating mammalian muscle

1979 • 136 citations

Voltage- and time-dependent chloride currents in chick skeletal muscle cells grown in tissue culture

1989 • 120 citations

Characterization of calcium currents in functionally mature mouse spinal motoneurons

2000 • 119 citations

Functional Integration of Embryonic Stem Cell-Derived Neurons in Hippocampal Slice Cultures

2003 • 113 citations

Development of glycine- and GABA-gated currents in rat spinal motoneurons

1995 • 112 citations

Apamin depresses selectively the after-hyperpolarization of cat spinal motoneurons

1987 • 110 citations

Development of L‐type calcium channels and a nifedipine‐sensitive motor activity in the postnatal mouse spinal cord

1999 • 110 citations

Stem cells in the treatment of Parkinson’s disease

2002 • 108 citations

Neurons derived in vitro from ES cells express homeoproteins characteristic of motoneurons and interneurons

1998 • 104 citations

Microtubule-associated protein 2 within axons of spinal motor neurons: associations with microtubules and neurofilaments in normal and beta,beta'-iminodipropionitrile-treated axons.

1985 • 89 citations

Regulation of repetitive firing in motoneurones by the afterhyperpolarization conductance

1971 • 76 citations

Progressive restriction of synaptic vesicle protein to the nerve terminal during development of the neuromuscular junction

1989 • 74 citations

MRI characteristics of acute and subacute brainstem and thalamic infarctions: value of T2- and diffusion-weighted sequences

2002 • 72 citations

Electrophysiological Properties of Rat Phrenic Motoneurons During Perinatal Development

1999 • 64 citations

Development of action potentials and apamin-sensitive after-potentials in mouse vestibular nucleus neurones

1998 • 63 citations

Overexpression of rat neuronal calcium sensor‐1 in rodent NG108‐15 cells enhances synapse formation and transmission

2001 • 53 citations

Molecular determinants of emerging excitability in rat embryonic motoneurons

2002 • 53 citations

Potassium currents in motoneurones

1995 • 52 citations

Guide to Data Acquisition and Analysis

1995 • 52 citations

Contractile activity regulates isoform expression and polysialylation of NCAM in cultured myotubes: involvement of Ca2+ and protein kinase C.

1996 • 50 citations

Voltage-sensitive calcium currents and their role in regulating phrenic motoneuron electrical excitability during the perinatal period

2001 • 45 citations

Functional motor neurons differentiating from mouse multipotent spinal cord precursor cells in culture and after transplantation into transected sciatic nerve

2003 • 41 citations

Afterpotentials and transduction properties in different types of central neurones.

1984 • 37 citations

Glutamate currents in mammalian spinal neurons: resolution of a paradox

1984 • 35 citations

Developmental Expression of the Small-Conductance Ca2+-Activated Potassium Channel SK2 in the Rat Retina

2001 • 29 citations

Excitatory and inhibitory transmission from dorsal root afferents to neonate rat motoneurons in vitro

1990 • 28 citations

Properties of spinal motoneurons and interneurons in the adult turtle: Provisional classification by cluster analysis

1998 • 27 citations

Development of G Protein‐mediated Ca²⁺ Channel Regulation in Mouse Embryonic Stem Cell‐derived Neurons

1997 • 26 citations

Current state of stem cell research for the treatment of Parkinson's disease

2002 • 24 citations

Stem cells in the treatment of amyotrophic lateral sclerosis (ALS)

2002 • 23 citations

Overexpression of rat neuronal calcium sensor-1 in rodent NG108-15 cells enhances synapse formation and transmission

2003 • 7 citations