Alpha-thrombin induces release of platelet-derived growth factor-like molecule(s) by cultured human endothelial cells.

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization.

1979 • 727 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

Human thrombins. Production, evaluation, and properties of alpha-thrombin.

1977 • 587 citations

Cultured endothelial cells produce a platelet-derived growth factor-like protein

1983 • 507 citations

Platelet-derived growth factor. I. High yield purification and evidence for multiple forms.

1982 • 457 citations

Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin.

1984 • 442 citations

The release of platelet-activating factor from human endothelial cells in culture.

1983 • 436 citations

Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides

1979 • 402 citations

Platelet-derived growth factor. II. Specific binding to cultured cells.

1982 • 366 citations

Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells.

1984 • 330 citations

An endothelial cell-derived growth factor.

1980 • 316 citations

Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells.

1986 • 310 citations

Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis

1985 • 286 citations

The measurement of thrombin in clotting blood by radioimmunoassay.

1976 • 235 citations

Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents.

1984 • 233 citations

Expression of the sis gene by endothelial cells in culture and in vivo.

1984 • 221 citations

Factors influencing endothelial cell proliferation in vitro

1978 • 205 citations

Binding of human thrombin to cultured human endothelial cells.

1979 • 193 citations

Thrombin-mediated release of factor VIII antigen from human umbilical vein endothelial cells in culture

1982 • 178 citations

Thrombin-induced gap formation in confluent endothelial cell monolayers in vitro

1983 • 164 citations

Regulation of production of a platelet‐derived growth factor‐like protein by cultured bovine aortic endothelial cells

1984 • 158 citations

The effect of calcium on the secretion of factor VIII-related antigen by cultured human endothelial cells

1983 • 151 citations

The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.

1985 • 143 citations

[8] methods for studying the platelet-derived growth factor receptor

1985 • 117 citations

Modulation of the sis Gene Transcript During Endothelial Cell Differentiation in Vitro

1985 • 117 citations

Effect of thrombin on the fibrinolytic activity of cultured bovine endothelial cells.

1979 • 107 citations

Thrombin Induces Thromboplastin Synthesis in Cultured Vascular Endothelial Cells

1985 • 71 citations

Evidence that the effects of thrombin on arachidonate metabolism in cultured human endothelial cells are not mediated by a high affinity receptor.

1980 • 53 citations

Detection of High Molecular Weight Forms of Platelet-Derived Growth Factor by Sequence-Specific Antisera

1984 • 36 citations

Thrombin-induced gap formation in confluent endothelial cell monolayers in vitro

1983 • 19 citations

The effect of thrombin on fibronectin in cultured human endothelial cells

1985 • 18 citations

Thrombin-mediated release of factor VIII antigen from human umbilical vein endothelial cells in culture

1982 • 14 citations