The chicken talpid³ gene encodesa novel protein essentialfor Hedgehog signaling

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Hedgehog signaling in animal development: paradigms and principles

2001 • 2,919 citations

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

2004 • 2,380 citations

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.

2004 • 2,260 citations

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

2004 • 2,149 citations

Estimating Synonymous and Nonsynonymous Substitution Rates Under Realistic Evolutionary Models

2000 • 1,666 citations

Vertebrate Smoothened functions at the primary cilium

2005 • 1,413 citations

Hedgehog signalling in the mouse requires intraflagellar transport proteins

2003 • 1,377 citations

Intrinsic Disorder in Cell-signaling and Cancer-associated Proteins

2002 • 1,174 citations

Hedgehog-Regulated Processing of Gli3 Produces an Anterior/Posterior Repressor Gradient in the Developing Vertebrate Limb

2000 • 1,019 citations

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

1999 • 772 citations

A mouse model of Greig cephalo–polysyndactyly syndrome: the extra–toesJ mutation contains an intragenic deletion of the Gli3 gene

1993 • 715 citations

Gli2, but notGli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

2002 • 671 citations

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

2002 • 591 citations

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

2005 • 539 citations

Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.

1995 • 504 citations

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

2002 • 484 citations

Progression of Vertebrate Limb Development Through SHH-Mediated Counteraction of GLI3

2002 • 381 citations

Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway

2001 • 368 citations

Chapter 10 Manipulating Gene Expression with Replication--Competent Retroviruses

1996 • 344 citations

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

2002 • 313 citations

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

2005 • 270 citations

Sonic hedgehog controls epaxial muscle determination through Myf5 activation

1999 • 269 citations

A model for anteroposterior patterning of the vertebrate limb based on sequential long- and short-range Shh signalling and Bmp signalling

2000 • 217 citations

MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription

2004 • 152 citations

Control of Muscle Cell-Type Specification in the Zebrafish Embryo by Hedgehog Signalling

1999 • 136 citations

The emergent design of the neural tube: prepattern, SHH morphogen and GLI code

2003 • 130 citations

Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta³) limb buds: Their relationships in the signalling cascade involved in limb patterning

1995 • 113 citations

Expression of ptc and gli genes in talpid 3 suggests bifurcation in Shh pathway*

1999 • 98 citations

The zebrafishiguanalocus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling

2004 • 98 citations

Ptc1 and Ptc2 Transcripts Provide Distinct Readouts of Hedgehog Signaling Activity during Chick Embryogenesis

2001 • 85 citations

Expression of β-catenin in the developing chick myotome is regulated by myogenic signals

2000 • 79 citations

Developmental abnormalities in the trunk and limbs of the talpid3 mutant of the fowl

1964 • 66 citations

Developmental abnormalities in the head region of the talpid3 mutant of the fowl

1964 • 57 citations

Constitutive Activation of Sonic Hedgehog Signaling in the Chicken Mutant talpid2: Shh-Independent Outgrowth and Polarizing Activity

1999 • 49 citations

The mis-expression of posterior Hox-4 genes in talpid (te3) mutant wings correlates with the absence of anteroposterior polarity

1992 • 41 citations

Craniofacial development in the talpid3 chicken mutant

2004 • 37 citations

Abnormalities in bone and cartilage development in thetalpid3mutant of the fowl

1968 • 18 citations

Analysis of the rdd locus in chicken: a model for human retinitis pigmentosa.

2003 • 17 citations