Inhibition of Tumor Necrosis Factor Alpha Alters Resistance toMycobacterium aviumComplex Infection in Mice

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation.

1993 • 1,058 citations

Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat.

1989 • 781 citations

Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome

1988 • 739 citations

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression.

1990 • 471 citations

The beige mutation in the mouse selectively impairs natural killer cell function

1979 • 467 citations

Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex.

1988 • 378 citations

Thalidomide inhibits the replication of human immunodeficiency virus type 1.

1993 • 230 citations

The beige mutation in the mouse. I. A stem cell predetermined impairment in natural killer cell function.

1979 • 198 citations

Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium avium infection

1994 • 182 citations

Elevated alpha–tumor necrosis factor levels in spinal fluid from HIV‐1–infected patients with central nervous system involvement

1991 • 170 citations

The beige mutation in the mouse. II. Selectivity of the natural killer (NK) cell defect.

1979 • 168 citations

Granulocyte Function in the Chediak-Higashi Syndrome of Mice

1974 • 157 citations

Treatment of experimental disseminated Mycobacterium avium complex infection in mice with recombinant IL-2 and tumor necrosis factor.

1989 • 125 citations

Bidirectional effects of cytokines on the growth of Mycobacterium avium within human monocytes.

1991 • 111 citations

Pentoxifylline (Trental) decreases the replication of the human immunodeficiency virus type 1 in human peripheral blood mononuclear cells and in cultured T cells [see comments]

1991 • 110 citations

Defective T-cell response in beige mutant mice

1982 • 94 citations

Pharmacologic Inhibitors of Tumor Necrosis Factor Production Exert Differential Effects in Lethal Endotoxemia and in Infection with Live Microorganisms in Mice

1995 • 71 citations

Production of TNF-alpha, IL-6 and TGF-beta, and expression of receptors for TNF-alpha and IL-6, during murine Mycobacterium avium infection.

1995 • 71 citations

Effect of rifabutin on disseminated Mycobacterium avium infections in thymectomized, CD4 T-cell-deficient mice

1990 • 43 citations

1,25 Dihydroxyvitamin D3-dependent inhibition of growth or killing of Mycobacterium avium complex in human macrophages is mediated by TNF and GM-CSF

1990 • 42 citations

Response to stimulation with recombinant cytokines and synthesis of cytokines by murine intestinal macrophages infected with the Mycobacterium avium complex

1995 • 41 citations

Modulation of Mycobacterium avium growth in vivo by cytokines: involvement of tumour necrosis factor in resistance to atypical mycobacteria

1991 • 39 citations

Beige mouse model for Mycobacterium avium complex disease

1995 • 38 citations

Pentoxifylline inhibits acute HIV-1 replication in human T cells by a mechanism not involving inhibition of tumour necrosis factor synthesis or nuclear factor-κB activation

1996 • 35 citations

Protection of mice from Mycobacterium avium infection by recombinant interleukin-12

1995 • 34 citations

Temporal effect of tumor necrosis factor alpha on murine macrophages infected with Mycobacterium avium

1997 • 27 citations

Susceptibility of Beige Mice toMycobacterium aviumComplex Infections by Different Routes of Challenge

1989 • 26 citations

Enhancement of antibacterial activity of clofazimine against Mycobacterium avium-Mycobacterium intracellulare complex infection induced by IFN-gamma is mediated by TNF-alpha

1997 • 23 citations

Immunological studies of NK cell-deficient beige mice. II. Analysis of T-lymphocyte functions in beige mice.

1989 • 16 citations

Assessment of New Therapies for Infection Due to the Mycobacterium avium Complex: Appropriate Use of In Vitro and In Vivo Testing

1994 • 14 citations

An analysis of the natural killer cell defect in beige mice

1981 • 14 citations

Induction of anti-mycobacterial and anti-listerial activity of human monocytes requires different activation signals

1991 • 12 citations

Pentoxifylline Aggravates Impairment in Tumor Necrosis Factor-a Secretion and Increases Mycobacterial Load in Macrophages from AIDS Patients with Disseminated Mycobacterium avium-intracellulare Complex Infection

1994 • 12 citations

Treatment of an Infected Murine Macrophage Cell Line (J774A.1) with Interferon-γ but Not Tumor Necrosis Factor-α or LiveMycobacterium intracellulareAlone Modulates the Expression of Adhesion Molecules

1997 • 8 citations

Pentoxifylline Impairs Macrophage Defense against Mycobacterium avium Complex

1995 • 7 citations

Pentoxifylline inhibits Ig kappa gene transcription and rearrangements in pre-B cells.

1998 • 6 citations

Pentoxifylline Inhibits Ig κ Gene Transcription and Rearrangements in Pre-B Cells

1998 • 5 citations