Minireview: Aquaporin 2 Trafficking

Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid

1993 • 2,625 citations

Identification and proteomic profiling of exosomes in human urine

2004 • 2,017 citations

Extracellular Calcium Sensing and Extracellular Calcium Signaling

2001 • 1,383 citations

Aquaporins in the Kidney: From Molecules to Medicine

2002 • 1,206 citations

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

1996 • 601 citations

Extracellular calcium sensing and signalling

2003 • 587 citations

Phosphorylation of Serine 256 Is Required for cAMP-dependent Regulatory Exocytosis of the Aquaporin-2 Water Channel

1997 • 465 citations

Nephrogenic Diabetes Insipidus

2001 • 432 citations

Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

1997 • 424 citations

Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct.

1997 • 358 citations

Identification of a Novel Syntaxin- and Synaptobrevin/VAMP-binding Protein, SNAP-23, Expressed in Non-neuronal Tissues

1996 • 356 citations

Protein kinase A phosphorylation is involved in regulated exocytosis of aquaporin-2 in transfected LLC-PK1 cells

1997 • 306 citations

Localization of the extracellular Ca²⁺/polyvalent cation-sensing protein in rat kidney

1998 • 305 citations

Hypokalemia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex.

1996 • 295 citations

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.

1995 • 294 citations

Molecular physiology of urinary concentrating mechanism: regulation of aquaporin water channels by vasopressin

1997 • 280 citations

Prostaglandin E receptors and the kidney

2000 • 277 citations

The ins and outs of aquaporin-2 trafficking

2003 • 266 citations

The aquaporin family of water channels in kidney

1995 • 261 citations

Role of the Ca2+-Sensing Receptor in Divalent Mineral Ion Homeostasis

1997 • 239 citations

The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel

2002 • 231 citations

Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells

2000 • 224 citations

Calcium and cyclic adenosine monophosphate as second messengers for vasopressin in the rat inner medullary collecting duct.

1988 • 220 citations

cAMP-dependent Phosphorylation Stimulates Water Permeability of Aquaporin-collecting Duct Water Channel Protein Expressed in Xenopus Oocytes

1995 • 217 citations

Regulation of Aquaporin-2 Trafficking by Vasopressin in the Renal Collecting Duct

2000 • 216 citations

Localization and regulation of PKA-phosphorylated AQP2 in response to V₂-receptor agonist/antagonist treatment

2000 • 197 citations

The Biochemistry of Neurotransmitter Secretion

1995 • 190 citations

Ca2+ and secretory-vesicle dynamics

1995 • 185 citations

The Subcellular Localization of an Aquaporin-2 Tetramer Depends on the Stoichiometry of Phosphorylated and Nonphosphorylated Monomers

2000 • 172 citations

Protein Kinase A Anchoring Proteins Are Required for Vasopressin-mediated Translocation of Aquaporin-2 into Cell Membranes of Renal Principal Cells

1999 • 169 citations

Large Scale Protein Identification in Intracellular Aquaporin-2 Vesicles from Renal Inner Medullary Collecting Duct

2005 • 164 citations

An Inhibitory Role of Rho in the Vasopressin-mediated Translocation of Aquaporin-2 into Cell Membranes of Renal Principal Cells

2001 • 158 citations

Expression of VAMP-2-like protein in kidney collecting duct intracellular vesicles. Colocalization with Aquaporin-2 water channels.

1995 • 158 citations

Vasopressin-elicited water and urea permeabilities are altered in IMCD in hypercalcemic rats

1998 • 155 citations

Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2

2004 • 142 citations

Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for Its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells

2004 • 141 citations

Syntaxin-4 is localized to the apical plasma membrane of rat renal collecting duct cells: possible role in aquaporin-2 trafficking.

1996 • 137 citations

Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra)

2005 • 137 citations

Prostaglandin E₂interaction with AVP: effects on AQP2 phosphorylation and distribution

2000 • 137 citations

The molecular basis of nephrogenic diabetes insipidus

1998 • 134 citations

Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue

1999 • 134 citations

cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI

2003 • 133 citations

Causes of reversible nephrogenic diabetes insipidus: A systematic review

2005 • 121 citations

Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells

2001 • 121 citations

Molecular and cellular defects in nephrogenic diabetes insipidus

2001 • 120 citations

Calcium-Sensing Receptor Activation of Rho Involves Filamin and Rho-Guanine Nucleotide Exchange Factor

2002 • 120 citations

Aquaporin-2 localization in clathrin-coated pits: inhibition of endocytosis by dominant-negative dynamin

2002 • 119 citations

Vasopressin depolymerizes apical F-actin in rat inner medullary collecting duct

1993 • 106 citations

Non-muscle Myosin II and Myosin Light Chain Kinase Are Downstream Targets for Vasopressin Signaling in the Renal Collecting Duct

2004 • 104 citations

Nephrogenic diabetes insipidus11In collaboration with The American Physiological Society, Thomas E. Andreoli, MD, Editor

1998 • 104 citations

The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho

2003 • 103 citations

Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells

2004 • 101 citations

The mechanisms of aquaporin control in the renal collecting duct

2008 • 100 citations

Dual Effects of Hypertonicity on Aquaporin-2 Expression in Cultured Renal Collecting Duct Principal Cells

2005 • 92 citations

Ser‐256 phosphorylation dynamics of aquaporin 2 during maturation from the endoplasmic reticulum to the vesicular compartment in renal cells

2003 • 91 citations

Evidence for dual signaling pathways for V2 vasopressin receptor in rat inner medullary collecting duct

1996 • 90 citations

Phosphorylation of Aquaporin-2 Does Not Alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles

1996 • 89 citations

Coupling of vasopressin‐induced intracellular Ca²⁺ mobilization and apical exocytosis in perfused rat kidney collecting duct

2002 • 88 citations

Expression and Functional Analysis of Water Channels in a Stably AQP2-transfected Human Collecting Duct Cell Line

1996 • 86 citations

Vasopressin depolymerizes F-actin in toad bladder epithelial cells

1991 • 86 citations

Direct demonstration of aquaporin-2 water channel recycling in stably transfected LLC-PK1 epithelial cells

1996 • 85 citations

Aquaporin‐2 trafficking is regulated by PDZ‐domain containing protein SPA‐1

2004 • 85 citations

SNAP-23 in rat kidney: colocalization with aquaporin-2 in collecting duct vesicles

1998 • 84 citations

Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct

1998 • 81 citations

SNARE expression and localization in renal epithelial cells suggest mechanism for variability of trafficking phenotypes

2002 • 81 citations

Water channel aquaporin-2 directly binds to actin

2004 • 80 citations

Hypertonicity Is Involved in Redirecting the Aquaporin-2 Water Channel into the Basolateral, Instead of the Apical, Plasma Membrane of Renal Epithelial Cells

2003 • 80 citations

Identification of a multiprotein “motor” complex binding to water channel aquaporin-2

2005 • 79 citations

The phosphatase inhibitor okadaic acid induces AQP2 translocation independently from AQP2 phosphorylation in renal collecting duct cells

2000 • 77 citations

Actin remodeling requires ERM function to facilitate AQP2 apical targeting

2005 • 75 citations

Cyclic AMP is sufficient for triggering the exocytic recruitment of aquaporin‐2 in renal epithelial cells

2003 • 74 citations

The 4.5Å Structure of Human AQP2

2005 • 72 citations

A Heterotrimeric G Protein of the Gi Family Is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial Cells

1998 • 71 citations

Functional involvement of VAMP/synaptobrevin-2 in cAMP-stimulated aquaporin 2 translocation in renal collecting duct cells

2002 • 71 citations

Differential regulation of AQP2 trafficking in endosomes by microtubules and actin filaments

2005 • 70 citations

Expression of syntaxins in rat kidney

1997 • 65 citations

V2-like vasopressin receptor mobilizes intracellular Ca2+ in rat medullary collecting tubules

1993 • 65 citations

Physiology in MedicineNephrogenic diabetes insipidus1

1998 • 64 citations

The aquaporin family of water channels in kidney.

1996 • 63 citations

Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling¹

2001 • 61 citations

Sensing of extracellular Ca2+ by parathyroid and kidney cells: Cloning and characterization of an extracellular Ca2+-sensing receptor

1995 • 56 citations

Altered expression of selected genes in kidney of rats with lithium-induced NDI

2005 • 56 citations

Extracellular Ca²⁺ decreases chloride reabsorption in rat CTAL by inhibiting cAMP pathway

1998 • 55 citations

Water and sodium balance in space

2001 • 55 citations

Phosphoinositide signaling in rat inner medullary collecting duct

1998 • 52 citations

Effect of cytochalasin D on the actin cytoskeleton of the toad bladder epithelial cell

1992 • 51 citations

Renal physiology of the extracellular calcium-sensing receptor

2002 • 49 citations

Selective Decrease in Urinary Aquaporin 2 and Increase in Prostaglandin E2 Excretion Is Associated with Postobstructive Polyuria in Human Congenital Hydronephrosis

2004 • 48 citations

Vasopressin and oxytocin receptors coupled to Ca2+ mobilization in rat inner medullary collecting duct

1993 • 46 citations

Specific coupling of a cation-sensing receptor to G protein alpha-subunits in MDCK cells

1997 • 44 citations

The effect of vasopressin on the cytoskeleton of the epithelial cell

1993 • 39 citations

Effect of nocodazole on the water permeability response to vasopressin in rabbit collecting tubules perfused in vitro.

1989 • 37 citations

Vesicle fusion proteins in rat inner medullary collecting duct and amphibian bladder

1995 • 27 citations

Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking

2004 • 23 citations

Nephrogenic diabetes insipidus: identification of the genetic defect

1993 • 22 citations

To what extent is microtubular network involved in antidiuretic response?

1988 • 22 citations

Principal cell-specific antigen and hormonal regulatory network in RC.SVtsA58 cell line

1994 • 19 citations

PGE2-induced inhibition of AVP-dependent cAMP accumulation in the OMCD of the rat kidney is cumulative with respect to the effects of ?2-adrenergic and A1-adenosine agonists, insensitive to pertussis toxin and dependent on extracellular calcium

1993 • 16 citations

Vasopressin, Hypercalciuria and Aquaporin – The Key Elements for Impaired Renal Water Handling in Astronauts?

2002 • 13 citations

Renal function in space: The link between osteoporosis, hypercalciuria, and aquaporins

2005 • 11 citations

Stimulation of Rho GDI release by ERM proteins

2000 • 10 citations

AVP-sensitive cAMP production is dependent on calmodulin in both MTAL and MCT

1988 • 9 citations

ADH-induced water permeability: What role for the microtubular network?

1988 • 7 citations

Microfilament Network Is Needed for the Endocytosis of Water Channels and Not for Apical Membrane Insertion Upon Vasopressin Action

2000 • 6 citations

The activation of protein kinase C prevents PGE2-induced inhibition of AVP-dependent cAMP accumulation in the rat outer medullary collecting tubule

1993 • 6 citations

Nephrogenic Diabetes Insipidus

1996 • 3 citations

[Nephrogenic diabetes insipidus].

1996 • 1 citations