Altered expression of alpha 4 beta 7, a gut homing integrin, by circulating and mucosal T cells in colonic mucosal inflammation.

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Cortisone in Ulcerative Colitis

1955 • 2,701 citations

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1993 • 1,762 citations

Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

1994 • 1,129 citations

Variation Between Observers in Describing Mucosal Appearances in Proctocolitis

1964 • 633 citations

Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

1996 • 558 citations

Cortisone in Ulcerative Colitis

1954 • 524 citations

Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes.

1994 • 350 citations

Selective expression of integrin alpha 4 beta 7 on a subset of human CD4+ memory T cells with Hallmarks of gut-trophism.

1993 • 254 citations

Expression of vascular adhesion molecules in inflammatory bowel disease

1992 • 217 citations

Adhesion molecules in inflammatory bowel disease.

1995 • 193 citations

A fundamental subdivision of circulating lymphocytes defined by adhesion to mucosal addressin cell adhesion molecule-1. Comparison with vascular cell adhesion molecule-1 and correlation with beta 7 integrins and memory differentiation.

1996 • 191 citations

Short-term course and prognosis of Crohn's disease

1974 • 165 citations

T cells, but not B cells, are required for bowel inflammation in interleukin 2-deficient mice.

1995 • 149 citations

Structure and function of adhesion receptors in leukocyte trafficking

1995 • 145 citations

Evidence that CD4⁺, but not CD8⁺ T cells are responsible for murine interleukin‐2‐deficient colitis

1995 • 144 citations

Reactivity of infiltrating T lymphocytes with microbial antigens in Crohn's disease

1991 • 137 citations

Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences.

1996 • 128 citations

Alpha 4 beta 7 integrin mediates B cell binding to fibronectin and vascular cell adhesion molecule-1. Expression and function of alpha 4 integrins on human B lymphocytes.

1993 • 128 citations

Peripheral monocyte and naive T-cell recruitment and activation in Crohn's disease

1995 • 127 citations

Cytokine production in patients with inflammatory bowel disease.

1992 • 116 citations

Remission of Crohn's Disease After Human Immunodeficiency Virus Infection

1988 • 107 citations

Regulation of lymphocyte homing into the brain during viral encephalitis at various stages of infection.

1996 • 97 citations

Chronic inflammatory bowel disease in childhood.

1982 • 74 citations

Mucosally activated circulating human B cells in diarrhea express homing receptors directing them back to the gut

1996 • 69 citations

Aetiology and pathogenesis of chronic inflammatory bowel disease

1994 • 55 citations

Comparison of lymphokine secretion and mRNA expression in the CD45RA⁺ and CD45RO⁺ subsets of human peripheral blood CD4⁺ and CD8⁺ lymphocytes

1995 • 54 citations

Membrane CD45R isoform exchange on CD4 T cells is rapid, frequent and dynamic in vivo

1994 • 51 citations

α_Eβ₇ and α₄β₇ integrins associated with intraepithelial and mucosal homing, are expressed on macrophages

1995 • 49 citations

Gut‐homing CD4⁺ T cell receptor αβ⁺ T cells in the pathogenesis of murine inflammatory bowel disease

1994 • 44 citations

Crohn's disease, ulcerative colitis, and normal intestinal lymphocytes express integrins in dissimilar patterns

1994 • 43 citations

Flow cytometric analysis of peripheral blood lymphocytes in ulcerative colitis and Crohn's disease.

1991 • 42 citations

Adhesion Molecule Expression on Vascular Endothelium and Nitroblue Tetrazolium Reducing Activity in Human Colonic Mucosa

1995 • 40 citations

Expression of the mucosal homing receptor α4β7 in malignant lymphomatous polyposis of the intestine

1994 • 35 citations

Specific regulation of VLA-4 and alpha 4 beta 7 integrin expression on human activated T lymphocytes.

1996 • 34 citations

Two-color immunofluorescence and flow cytometric analysis of lamina propria lymphocyte subsets in ulcerative colitis and Crohn's Disease

1991 • 32 citations

Immune Events Associated with Inflammatory Bowel Disease

1990 • 31 citations

Integrin α4β7 Co-Stimulation of Human Peripheral Blood T Cell Proliferation

1994 • 29 citations

Similar but nonidentical amino acid residues on vascular cell adhesion molecule-1 are involved in the interaction with alpha 4 beta 1 and alpha 4 beta 7 under different activity states.

1995 • 24 citations

Selective recruitment of lymphocyte subsets to the inflamed appendix

1995 • 18 citations

Phenotypical characterization of peripheral blood T cells in patients with coeliac disease: elevation of antigen-primed CD45RO+ T lymphocytes.

1995 • 17 citations

Interleukin-2 receptor α and β chain expression by circulating αβ and γδ T cells in inflammatory bowel disease

1995 • 12 citations

Deleted Work

1955 • 0 citations