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Management of Infections Due to Antibiotic-Resistant Streptococcus pneumoniae

Data up to Jan 2025

Published1998
Citations236
References139

Total Citations Per Year

Abstract

References (139)

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1996 • 97 citations

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1995 • 89 citations

Resistance to penicillin and non-beta-lactam antibiotics of Streptococcus pneumoniae at a childrenʼs hospital

1994 • 89 citations

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1979 • 76 citations

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1987 • 75 citations

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1997 • 75 citations

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1996 • 75 citations

Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci

1996 • 75 citations

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1992 • 72 citations

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1976 • 69 citations

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1996 • 63 citations

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1996 • 61 citations

Cefprozil treatment of persistent and recurrent acute otitis media

1997 • 57 citations

Steroid Therapy for Bacterial Meningitis

1995 • 56 citations

MIC and time-kill study of activities of DU-6859a, ciprofloxacin, levofloxacin, sparfloxacin, cefotaxime, imipenem, and vancomycin against nine penicillin-susceptible and -resistant pneumococci

1996 • 56 citations

In vivo efficacy of a broad-spectrum cephalosporin, ceftriaxone, against penicillin-susceptible and -resistant strains of Streptococcus pneumoniae in a mouse pneumonia model

1994 • 55 citations

In vivo efficacy of a new fluoroquinolone, sparfloxacin, against penicillin-susceptible and -resistant and multiresistant strains of Streptococcus pneumoniae in a mouse model of pneumonia

1992 • 54 citations

MIDDLE EAR FLUID CONCENTRATIONS OF AMOXICILLIN AFTER LARGE DOSAGES IN CHILDREN WITH ACUTE OTITIS MEDIA

1997 • 54 citations

Breakthrough bacteremia and meningitis during treatment with cephalosporins parenterally for pneumococcal pneumonia

1998 • 53 citations

Middle ear fluid concentrations of amoxicillin after large dosages in children with acute otitis media*

1998 • 53 citations

Cerebrospinal fluid bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in children with meningitis treated with high-dosage cefotaxime

1997 • 53 citations

In vitro activities of oxazolidinones U-100592 and U-100766 against penicillin-resistant and cephalosporin-resistant strains of Streptococcus pneumoniae

1996 • 53 citations

Trovafloxacin, a new fluoroquinolone with potent activity against Streptococcus pneumoniae

1997 • 52 citations

Invasive pneumococci with high level penicillin and cephalosporin resistance at a mid-south children's hospital.

1994 • 51 citations

Pyogenic Bacterial Pneumonia in Human Immunodeficiency Virus–Infected Inpatients: A Clinical, Radiological, Microbiological, and Epidemiological Study

1998 • 50 citations

Concentrations of ceftriaxone in cerebrospinal fluid of children with meningitis receiving dexamethasone therapy

1994 • 49 citations

Complicated Parapneumonic Effusions in Children Caused by Penicillin-NonsusceptibleStreptococcus pneumoniae

1998 • 49 citations

Evaluation of CP-99,219, a new fluoroquinolone, for treatment of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis

1995 • 48 citations

Effect of increased dosages of amoxicillin in treatment of experimental middle ear otitis due to penicillin-resistant Streptococcus pneumoniae

1993 • 47 citations

Trovafloxacin in treatment of rabbits with experimental meningitis caused by high-level penicillin-resistant Streptococcus pneumoniae

1997 • 46 citations

Clinical implications of penicillin and ceftriaxone resistance among children with pneumococcal bacteremia

1999 • 46 citations

Human Pharmacokinetics and Distribution in Various Tissues of Ceftriaxone

1986 • 45 citations

MENINGITIS WITH BETA-LACTAM-RESISTANT STREPTOCOCCUS PNEUMONIAE

1993 • 45 citations

Risk/Benefit in the Treatment of Children with Imipenem-Cilastatin for Meningitis Caused by Penicillin-Resistant Pneumococcus

1993 • 42 citations

Penicillin- and cephalosporin-resistant strains of Streptococcus pneumoniae causing sepsis and meningitis in children with sickle cell disease

1995 • 42 citations

INVASIVE PNEUMOCOCCI WITH HIGH LEVEL PENICILLIN AND CEPHALOSPORIN RESISTANCE AT A MID-SOUTH CHILDRENʼS HOSPITAL

1994 • 41 citations

The bactericidal activity of levofloxacin compared with ofloxacin, D- ofloxacin, ciprofloxacin, sparfloxacin and cefotaxime against Streptococcus pneumoniae

1997 • 41 citations

Levels of Cefotaxime in Body Fluids and Tissues: A Review

1982 • 40 citations

PENETRATION OF CEFTRIAXONE INTO THE MIDDLE EAR FLUID OF CHILDREN

1998 • 40 citations

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1997 • 39 citations

Pharmacokinetics of Vancomycin in Normal Subjects and in Patients with Reduced Renal Function

1981 • 39 citations

Serum protein binding and extravascular diffusion of methoxyimino cephalosporins. Time courses of free and total concentrations of cefotaxime and ceftriaxone in serum and pleural exudate

1990 • 38 citations

Treatment of Penicillin-Resistant Pneumococcal Bacteremia in Neutropenic Patients with Cancer

1997 • 38 citations

Bactericidal activity against intermediately cephalosporin-resistant Streptococcus pneumoniae in cerebrospinal fluid of children with bacterial meningitis treated with high doses of cefotaxime and vancomycin

1997 • 38 citations

In vitro and in vivo antibacterial activities of KRM-1648 and KRM-1657, new rifamycin derivatives

1994 • 38 citations

Efficacies of cefotaxime and ceftriaxone in a mouse model of pneumonia induced by two penicillin- and cephalosporin-resistant strains of Streptococcus pneumoniae

1996 • 34 citations

Antibiotic-resistant pneumococcal disease in children at Baragwanath Hospital, Johannesburg

1986 • 33 citations

Comparative activities of LY 333328, a new glycopeptide, against penicillin-susceptible and -resistant pneumococci

1996 • 31 citations

Comparative In Vitro Killing Activities of Meropenem, Imipenem, Ceftriaxone, and Ceftriaxone plus Vancomycin at Clinically Achievable Cerebrospinal Fluid Concentrations against Penicillin-Resistant Streptococcus pneumoniae Isolates from Children with Meningitis

1998 • 31 citations

Nosocomial epiglottitis associated with penicillin- and cephalosporin-resistant Streptococcus pneumoniae bacteremia

1994 • 30 citations

MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci

1996 • 29 citations

In vitro activities of five fluoroquinolone compounds against strains of Streptococcus pneumoniae with resistance to other antimicrobial agents

1996 • 29 citations

Twice Daily Cefpodoxime Proxetil Compared with Thrice Daily Amoxicillin/Clavulanic Acid for Treatment of Acute Otitis Media in Children

1994 • 26 citations

Meningitis From a Pneumococcus Moderately Resistant to Penicillin

1979 • 26 citations

Efficacy and safety of grepafloxacin 600 mg daily for 10 days in patients with community-acquired pneumonia

1997 • 24 citations

Decreased susceptibility to imipenem among penicillin-resistant Streptococcus pneumoniae [published erratum appears in J Antimicrob Chemother 1997 Sep;40(3):462]

1997 • 24 citations

Therapy for children with invasive pneumococcal infections. American Academy of Pediatrics Committee on Infectious Diseases.

1997 • 23 citations

Rifabutin for Experimental Pneumococcal Meningitis

1997 • 23 citations

Penicillin-Resistant Pneumococci From Pediatric Patients in the Washington, DC, Area

1995 • 23 citations

Failure of cefotaxime treatment in an adult with Streptococcus pneumoniae meningitis

1997 • 23 citations

In vitro activity of the trinem sanfetrinem (GV104326) against gram-positive organisms

1996 • 22 citations

Treatment of experimental pneumonia due to penicillin-resistant Streptococcus pneumoniae in immunocompetent rats

1997 • 22 citations

The penetration of ceftriaxone into synovial fluid of the inflamed joint

1985 • 20 citations

Ceftriaxone Therapy in Pediatric Patients

1983 • 20 citations

Inoculum effect and bactericidal activity of cefditoren and other antibiotics againstStreptococcus pneumoniae, Haemophilus influenzae, andNeisseria meningitidis

1996 • 19 citations

Development of experimental pneumonia by infection with penicillin-insensitive Streptococcus pneumoniae in guinea pigs and their treatment with amoxicillin, cefotaxime, and meropenem

1996 • 19 citations

Failure of cefotaxime treatment in two children with meningitis caused by highly penicillin‐resistant Streptococcus pneumoniae

1995 • 19 citations

Levofloxacin in vitro activity against bacteremic isolates of Streptococcus pneumoniae

1996 • 18 citations

Ceftriaxone (Ro 13-9904) therapy of serious infection

1982 • 17 citations

Efficacy of single-dose ceftriaxone in experimental otitis media induced by penicillin- and cephalosporin-resistant Streptococcus pneumoniae

1996 • 17 citations

Efficacy of clarithromycin treatment of acute otitis media caused by infection with penicillin-susceptible, -intermediate, and -resistant Streptococcus pneumoniae in the chinchilla

1996 • 16 citations

Septic arthritis and osteomyelitis caused by penicillin and cephalosporin-resistant Streptococcus pneumoniae in a children's hospital

1996 • 16 citations

Appearance of resistance to beta-lactam antibiotics during therapy for Streptococcus pneumoniae meningitis

1995 • 14 citations

PENETRATION OF CEFPODOXIME INTO MIDDLE EAR FLUID IN PEDIATRIC PATIENTS WITH ACUTE OTITIS MEDIA

1997 • 11 citations

Penetration of Third-Generation Cephalosporins into Human Peritoneal Tissue

1989 • 10 citations

Activity of trovafloxacin against blood isolates ofStreptococcus pneumoniae in Sweden

1996 • 10 citations

Antimicrobial activity and spectrum of sparfloxacin tested against erythromycin-resistant Streptococcus pneumoniae isolates

1996 • 10 citations

PENICILLIN AND TRIMETHOPRIM-SULFAMETHOXAZOLE-RESISTANT PNEUMOCOCCI ISOLATED FROM BLOOD CULTURES OF THREE INFANTS IN METROPOLITAN WASHINGTON, DC

1991 • 9 citations

In vitro activity of sanfetrinem (GV104326), a new trinem antimicrobial agent, versus Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis

1996 • 9 citations

Pharmacokinetics of Ceftriaxone and Its Relation to Concentrations in Extravascular Compartments

1985 • 9 citations

Concentration of cefuroxime in middle ear effusion of children with acute otitis media

1997 • 8 citations

Meningitis from a pneumococcus moderately resistant to penicillin

1979 • 7 citations

MIDDLE EAR EFFUSION CONCENTRATIONS OF CEFIXIME DURING ACUTE OTITIS MEDIA WITH EFFUSION AND OTITIS MEDIA WITH EFFUSION

1997 • 7 citations

Concerns of Secondary Fever in Streptococcus pneumoniae Meningitis in an Era of Increasing Antibiotic Resistance

1996 • 2 citations

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