The Continued Emergence of Drug-Resistant Streptococcus pneumoniae in the United States: An Update from the Centers for Disease Control and Prevention's Pneumococcal Sentinel Surveillance System

The Protective Efficacy of Polyvalent Pneumococcal Polysaccharide Vaccine

1991 • 1,066 citations

Trends in Antimicrobial Drug Prescribing Among Office-Based Physicians in the United States

1995 • 808 citations

Estimation of a Common Effect Parameter from Sparse Follow-Up Data

1985 • 780 citations

Management of Infections Caused by Antibiotic-Resistant Streptococcus Pneumoniae

1994 • 579 citations

Emergence of Drug-Resistant Pneumococcal Infections in the United States

1994 • 556 citations

Multiple-Antibiotic-Resistant Pathogenic Bacteria -- A Report on the Rockefeller University Workshop

1994 • 434 citations

Intercontinental Spread of a Multiresistant Clone of Serotype 23F Streptococcus pneumoniae

1991 • 424 citations

The Spread of Multiply Resistant Streptococcus pneumoniae at a Day Care Center in Ohio

1992 • 392 citations

Risk Factors and Response to Antibiotic Therapy in Adults with Bacteremic Pneumonia Caused by Penicillin-Resistant Pneumococci

1987 • 383 citations

Pneumococcal Disease after Pneumococcal Vaccination

1980 • 335 citations

Horizontal transfer of multiple penicillin‐binding protein genes, and capsular biosynthetic genes, in natural populations of Streptococcus pneumoniae

1991 • 315 citations

Antimicrobial resistance among respiratory isolates of Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae in the United States

1990 • 308 citations

Antimicrobial Resistance of Streptococcus pneumoniae in the United States, 1979-1987

1991 • 269 citations

Penicillin-resistant Streptococcus pneumoniae in acute otitis media

1995 • 266 citations

Evolution of penicillin resistance in Streptococcus pneumoniae; the role of Streptococcus mitis in the formation of a low affinity PBP2B in S. pneumoniae

1993 • 261 citations

Serotype Distribution of Streptococcus pneumoniae Infections among Preschool Children in the United States, 1978-1994: Implications for Development of a Conjugate Vaccine

1995 • 250 citations

Pneumococcal disease: prospects for a new generation of vaccines

1994 • 196 citations

Pneumococcal Polysaccharide-Meningococcal Outer Membrane Protein Complex Conjugate Vaccine Is Immunogenic in Infants and Children

1995 • 185 citations

Minimizing the Impact of Drug-Resistant Streptococcus pneumoniae (DRSP)

1996 • 169 citations

Transmission of Multidrug-Resistant Serotype 23F Streptococcus pneumoniae in Group Day Care: Evidence Suggesting Capsular Transformation of the Resistant Strain In Vivo

1995 • 165 citations

High prevalence of multidrug-resistant Streptococcus pneumoniae among children in a rural Kentucky community

1995 • 164 citations

Penicillin-Resistant Streptococcus pneumoniae Strains Recovered in Houston: Identification and Molecular Characterization of Multiple Clones

1993 • 149 citations

Immunogenicity of heptavalent pneumococcal conjugate vaccine in infants

1996 • 146 citations

Relapsing pneumococcal meningitis: Isolation of an organism with decreased susceptibility to penicillin G

1974 • 141 citations

Colonization with penicillin-resistant Streptococcus pneumoniae in a child-care center

1995 • 117 citations

Susceptibility of Streptococcus pneumoniae to Penicillin: A Prospective Microbiological and Clinical Study

1992 • 114 citations

Increased rate of isolation of penicillin-resistant Streptococcus pneumoniae in a children's hospital and in vitro susceptibilities to antibiotics of potential therapeutic use

1992 • 109 citations

A randomized comparison of three bivalent Streptococcus pneumoniae glycoprotein conjugate vaccines in young children

1994 • 104 citations

Identification of multiple clones of extended-spectrum cephalosporin-resistant Streptococcus pneumoniae isolates in the United States

1995 • 92 citations

Invasive Disease Due to Streptococcus pneumoniae in an Area with a High Rate of Relative Penicillin Resistance

1987 • 91 citations

Resistance to penicillin and non-beta-lactam antibiotics of Streptococcus pneumoniae at a childrenʼs hospital

1994 • 89 citations

Serotype Distribution and Antimicrobial Resistance Patterns of Invasive Isolates ofStreptococcus pneumoniae:Alaska, 1991–1998

2000 • 89 citations

Appropriateness of antibiotic therapy in long-term care facilities

1987 • 86 citations

Development of interpretive criteria and quality control limits for broth microdilution and disk diffusion antimicrobial susceptibility testing of Streptococcus pneumoniae

1994 • 74 citations

The Escalating Problem of Antimicrobial Resistance in Streptococcus pneumoniae

1992 • 68 citations

A penicillin-resistant pneumococcus

1978 • 66 citations

Invasive Pneumococcal Disease in Central Oklahoma: Emergence of High-Level Penicillin Resistance and Multiple Antibiotic Resistance

1993 • 64 citations

Antibiotic-Resistant Isolates of Streptococcus pneumoniae from Clinical Specimens: A Cluster of Serotype 19A Organisms in Brooklyn, New York

1986 • 61 citations

Multiple Antimicrobial Resistance of Pneumococci in Children with Otitis Media, Bacteremia, and Meningitis in Slovakia

1995 • 52 citations

The Clinical and Molecular Epidemiology of Bacteremias at a University Hospital Caused by Pneumococci Not Susceptible to Penicillin

1995 • 48 citations

Antimicrobial resistance in Streptococcus pneumoniae: can immunization prevent its spread?

1994 • 41 citations

Fatal Pneumonia Due to a Tetracycline-Resistant Pneumococcus

1966 • 20 citations

Emergence of Penicillin-Resistant Invasive Pneumococci in a Single American Community

1995 • 13 citations

Evidence for a Clonal Origin of Relative Penicillin Resistance among Type 9L Pneumococci in Northwestern Canada

1992 • 10 citations