Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption

2000 • 1,169 citations

Evidence for the Secretion of an Osteoclast Stimulating Factor in Myeloma

1974 • 681 citations

Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord

2000 • 496 citations

Osteoprotegerin Produced by Osteoblasts Is an Important Regulator in Osteoclast Development and Function*

2000 • 381 citations

Immunological Characterization of Circulating Osteoprotegerin/Osteoclastogenesis Inhibitory Factor: Increased Serum Concentrations in Postmenopausal Women with Osteoporosis

1999 • 378 citations

Recruitment of new osteoblasts and osteoclasts is the earliest critical event in the pathogenesis of human multiple myeloma.

1991 • 256 citations

Biochemical Markers of Bone Metabolism

2011 • 250 citations

Serum syndecan-1: a new independent prognostic marker in multiple myeloma

2000 • 241 citations

Mechanisms of bone destruction in multiple myeloma: the importance of an unbalanced process in determining the severity of lytic bone disease.

1989 • 240 citations

The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro.

1997 • 239 citations

Cell–cell contact between marrow stromal cells and myeloma cells via VCAM-1 and α4β1-integrin enhances production of osteoclast-stimulating activity

2000 • 201 citations

Cell–cell contact between marrow stromal cells and myeloma cells via VCAM-1 and α4β1-integrin enhances production of osteoclast-stimulating activity

2000 • 178 citations

Transmembrane and cytoplasmic domains of syndecan mediate a multi-step endocytic pathway involving detergent-insoluble membrane rafts

2000 • 146 citations

Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins

2000 • 125 citations

Hepatocyte Growth Factor (HGF) Induces Interleukin-11 Secretion From Osteoblasts: A Possible Role for HGF in Myeloma-Associated Osteolytic Bone Disease

1999 • 118 citations

Biochemical markers of bone metabolism reflect osteoclastic and osteoblastic activity in multiple myeloma

2000 • 98 citations

Interferon-α 2b Added to Melphalan-Prednisone for Initial and Maintenance Therapy in Multiple Myeloma

1996 • 83 citations

Prognostic evaluation in multiple myeloma: an analysis of the impact of new prognostic factors

1999 • 62 citations

Serum markers of bone metabolism in multiple myeloma: prognostic value of the carboxy‐terminal telopeptide of type I collagen (ICTP)

1997 • 59 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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