A nuclease-hypersensitive element of the human c-myc promoter interacts with a transcription initiation factor.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma

1983 • 732 citations

Site-Specific Oligonucleotide Binding Represses Transcription of the Human c- myc Gene in Vitro

1988 • 707 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

The chemistry and biology of unusual DNA structures adopted by oligopurine · oligopyrimidine sequences

1988 • 543 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

An altered DNA conformation detected by S1 nuclease occurs at specific regions in active chick globin chromatin

1982 • 448 citations

Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in burkitt lymphoma

1984 • 443 citations

DNAase I-hypersensitive sites of chromatin

1981 • 410 citations

Purification and Properties of Drosophila Heat Shock Activator Protein

1987 • 388 citations

Chromosomal breakpoints and structural alterations of the c-myc locus differ in endemic and sporadic forms of Burkitt lymphoma.

1986 • 371 citations

Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site.

1987 • 355 citations

Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences

1968 • 308 citations

Rapid Cytoplasmic Turnover of c-myc mRNA: Requirement of the 3′ Untranslated Sequences

1987 • 302 citations

The Structure and Evolution of the Human /?-Globin Gene Family

1980 • 301 citations

Structure refined to 2Å of a nicked DNA octanucleotide complex with DNase I

1988 • 293 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE.

1987 • 278 citations

Unusual DNA Structures

2011 • 277 citations

Novel promoter upstream of the human c-myc gene and regulation of c-myc expression in B-cell lymphomas.

1986 • 176 citations

Modulation of epidermal growth factor receptor proto-oncogene transcription by a promoter site sensitive to S1 nuclease.

1988 • 143 citations

Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1.

1989 • 130 citations

Regulatory elements that modulate expression of human c-myc.

1987 • 129 citations

A sequence conserved in both the chicken and mouse alpha 2(I) collagen promoter contains sites sensitive to S1 nuclease.

1984 • 118 citations

Two distinct mechanisms of transcriptional control operate on c-myc during differentiation of HL60 cells.

1988 • 106 citations

DNA structure equilibria in the human c-myc gene

1987 • 99 citations

The c-myc gene encodes superimposed RNA polymerase II and III promoters

1987 • 99 citations

An erythrocyte-specific protein that binds to the poly(dG) region of the chicken beta-globin gene promoter.

1988 • 99 citations

Trans-acting elements modulate expression of the human c-myc gene in Burkitt lymphoma cells.

1986 • 95 citations

Unusual DNA structures in the adenovirus genome.

1986 • 87 citations

Target sequences for cis-acting regulation within the dual promoter of the human c-myc gene.

1987 • 69 citations

Structure and function of the S1 nuclease-sensitive site in the adenovirus late promoter

1986 • 58 citations

A molecular model for gene repression.

1966 • 48 citations

A plasmacytoma-specific factor binds the c-myc promoter region.

1987 • 45 citations

Synthesis and processing of simian virus 40-specific RNA in adenovirus-infected, simian virus 40-transformed human cells

1983 • 39 citations

Unusual DNA sequences located within the promoter region and the first intron of the chicken pro-alpha 1(I) collagen gene.

1987 • 34 citations

Accurate and Efficient Transcription of Human c-myc Genes Injected into Xenopus laevis Oocytes

1985 • 19 citations

Specific transcription of an adenoviral gene that possesses no TATA sequence homology in extracts of HeLa cells.

1984 • 17 citations