Elongated Telomeres inscidMice

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

1995 • 862 citations

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1998 • 636 citations

DNA-Dependent Kinase (p350) as a Candidate Gene for the Murine SCID Defect

1995 • 610 citations

Telomeres in the mouse have large inter-chromosomal variations in the number of T ₂ AG ₃ repeats

1997 • 490 citations

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

1996 • 478 citations

Yeast Ku as a Regulator of Chromosomal DNA End Structure

1998 • 432 citations

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene

1995 • 386 citations

TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

1995 • 370 citations

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

1998 • 369 citations

Accelerated telomere shortening in ataxia telangiectasia

1996 • 334 citations

The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities

1998 • 245 citations

Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

1997 • 196 citations

DNA-PK: at the cross-roads of biochemistry and genetics

1997 • 169 citations

Telomere length, chromatin structure and chromosome fusigenic potential

1997 • 92 citations