Homology modelling of the ligand-binding domain of glucocorticoid receptor: binding site interactions with cortisol and corticosterone

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase‐trimethoprim, a drug‐receptor system

1988 • 1,947 citations

Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

1987 • 1,920 citations

Progressive sequence alignment as a prerequisitetto correct phylogenetic trees

1987 • 1,899 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Atomic structure of progesterone complexed with its receptor

1998 • 654 citations

Co-activators and co-repressors in the integration of transcriptional responses

1998 • 606 citations

Steroid–Cell Interactions

1974 • 592 citations

Structural Evidence for Ligand Specificity in the Binding Domain of the Human Androgen Receptor

2000 • 587 citations

The neuronal mineralocorticoid eeceptor as a mediator of glucocorticoid response

1988 • 576 citations

Atlas of Steroid Structure

1975 • 535 citations

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

1998 • 516 citations

Domains of the Human Androgen Receptor Involved in Steroid Binding, Transcriptional Activation, and Subcellular Localization

1991 • 513 citations

Mineralocorticoid and Glucocorticoid Receptor Activities Distinguished by Nonreceptor Factors at a Composite Response Element

1993 • 461 citations

Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH2-terminal Domain

1999 • 354 citations

Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands

1993 • 299 citations

The Androgen Receptor Amino-Terminal Domain Plays a Key Role in p160 Coactivator-Stimulated Gene Transcription

1999 • 268 citations

THE NUCLEAR HORMONE RECEPTOR GENE SUPERFAMILY

1995 • 260 citations

Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor.

1993 • 190 citations

Antagonism in the humanmineralocorticoid receptor

1998 • 171 citations

Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors

1999 • 166 citations

Domain structure of the glucocorticoid receptor protein.

1987 • 121 citations

The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor.

1996 • 83 citations

A conserved carboxy-terminal subdomain is important for ligand interpretation and transactivation by nuclear receptors.

1994 • 58 citations

Valine 571 Functions as a Regional Organizer in Programming the Glucocorticoid Receptor for Differential Binding of Glucocorticoids and Mineralocorticoids

1999 • 24 citations

Crystal and molecular structure of cortisol (11β,17α,21-trihydroxypregn-4-ene-3,20-dione) methanol solvate

1973 • 22 citations

Novel cDNA sequence possibly generated by alternative splicing of a mouse glucocorticoid receptor gene transcript from Shionogi carcinoma 115

1989 • 10 citations