Activation of Mitogen-Activated Protein Kinases in Human Heart During Cardiopulmonary Bypass

The MAPK signaling cascade

1995 • 3,300 citations

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

1994 • 2,659 citations

Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats.

1997 • 683 citations

Oxidative Stress-Induced Actin Reorganization Mediated by the p38 Mitogen-Activated Protein Kinase/Heat Shock Protein 27 Pathway in Vascular Endothelial Cells

1997 • 569 citations

Stimulation of the Stress-Activated Mitogen-Activated Protein Kinase Subfamilies in Perfused Heart

1996 • 531 citations

“Stress-Responsive” Mitogen-Activated Protein Kinases (c-Jun N-Terminal Kinases and p38 Mitogen-Activated Protein Kinases) in the Myocardium

1998 • 510 citations

Inhibition of p38 Mitogen-Activated Protein Kinase Decreases Cardiomyocyte Apoptosis and Improves Cardiac Function After Myocardial Ischemia and Reperfusion

1999 • 504 citations

Cellular mechanisms of cardiac hypertrophy

1998 • 409 citations

Stimulation of “Stress-regulated” Mitogen-activated Protein Kinases (Stress-activated Protein Kinases/c-Jun N-terminal Kinases and p38-Mitogen-activated Protein Kinases) in Perfused Rat Hearts by Oxidative and Other Stresses

1998 • 320 citations

Oxidative Stress Disrupts Insulin-induced Cellular Redistribution of Insulin Receptor Substrate-1 and Phosphatidylinositol 3-Kinase in 3T3-L1 Adipocytes

1999 • 307 citations

PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits

1999 • 217 citations

Activation of c-Jun N-Terminal Kinases and p38-Mitogen-activated Protein Kinases in Human Heart Failure Secondary to Ischaemic Heart Disease

1999 • 216 citations

MAPK activation determines renal epithelial cell survival during oxidative injury

1999 • 198 citations

Oxidative Stress Induces DNA Fragmentation and Caspase Activation Via the c-Jun NH2-terminal Kinase Pathway in H9c2 Cardiac Muscle Cells

1998 • 193 citations

Hypoxia/Reoxygenation Stimulates Jun Kinase Activity Through Redox Signaling in Cardiac Myocytes

1997 • 179 citations

Hypoxia and Hypoxia/Reoxygenation Activate p65PAK, p38Mitogen-Activated Protein Kinase (MAPK), and Stress-Activated Protein Kinase (SAPK) in Cultured Rat Cardiac Myocytes

1997 • 124 citations

Calcium Influx Activates Extracellular-regulated Kinase/Mitogen-activated Protein Kinase Pathway through a Calmodulin-sensitive Mechanism in PC12 Cells

1999 • 95 citations

Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart

1998 • 87 citations

p38 MAPK Inhibition Decreases TNF-α Production and Enhances Postischemic Human Myocardial Function

1999 • 86 citations

Regulation of mitogen-activated protein kinase cascade in adult rat heart preparations in vitro.

1994 • 80 citations

Activation of Mitogen-activated Protein Kinases in in vivo Ischemia/Reperfused Myocardium in Rats

1999 • 70 citations

Can clonidine, enoximone, and enalaprilat help to protect the myocardium against ischaemia in cardiac surgery?

1996 • 55 citations

Adenosine Prevents Hyperkalemia-Induced Calcium Loading in Cardiac Cells: Relevance for Cardioplegia

1997 • 44 citations

Hypothermic stress leads to activation of Ras-Erk signaling

1999 • 37 citations

Regulation of mitogen-activated protein kinase cascade in adult rat heart preparations in vitro.

1994 • 37 citations

Captopril in Cardioplegia and Reperfusion: Protective Effects on the Ischemic Heart

1997 • 26 citations

Beneficial Effects of Angiotensin I Converting Enzyme Inhibitor on Post-ischemic Contractile Function of Perfused Rat Heart

1996 • 15 citations