Validation of [123I]β-CIT SPECT to Assess Serotonin Transporters In Vivo in Humans: a Double-Blind, Placebo-Controlled, Crossover Study with the Selective Serotonin Reuptake Inhibitor Citalopram

An Inventory for Measuring Depression

1961 • 36,954 citations

Co-Planar Stereotaxic Atlas of the Human Brain

1988 • 11,912 citations

Statistical parametric maps in functional imaging: A general linear approach

1994 • 9,606 citations

Co-planar stereotaxic atlas of the human brain

1989 • 7,557 citations

A Three-Dimensional Statistical Analysis for CBF Activation Studies in Human Brain

1992 • 2,062 citations

Detecting Activations in PET and fMRI: Levels of Inference and Power

1996 • 1,156 citations

The spectrum of behaviors influenced by serotonin

1998 • 1,126 citations

Neuropathologic changes in Alzheimer's disease.

2003 • 544 citations

Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography

1998 • 507 citations

Serotonin Transporter Occupancy of Five Selective Serotonin Reuptake Inhibitors at Different Doses: An [¹¹C]DASB Positron Emission Tomography Study

2004 • 485 citations

[123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease.

1997 • 412 citations

SPECT imaging of dopamine and serotonin transporters with [¹²³I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates

1993 • 357 citations

Altered Serotonin Innervation Patterns in the Forebrain of Monkeys Treated with (±)3,4-Methylenedioxymethamphetamine Seven Years Previously: Factors Influencing Abnormal Recovery

1999 • 340 citations

Reduced Central Serotonin Transporters in Alcoholism

1998 • 316 citations

(±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals

2000 • 296 citations

Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users

1999 • 286 citations

Graphical, Kinetic, and Equilibrium Analyses of in vivo [¹²³I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects

1994 • 274 citations

Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons

2001 • 253 citations

Autoradiography of antidepressant binding sites in the human brain: localization using [3h]imipramine and [3h]paroxetine

1988 • 219 citations

High‐affinity binding of [¹²⁵I]RTI‐55 to dopamine and serotonin transporters in rat brain

1992 • 211 citations

SPECT imaging of dopamine and serotonin transporters with [123I]?-CIT. Binding kinetics in the human brain

1993 • 200 citations

Cortical Serotonin Transporter Density and Verbal Memory in Individuals Who Stopped Using 3,4-Methylenedioxymethamphetamine (MDMA or "Ecstasy")

2001 • 196 citations

Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users

2003 • 195 citations

Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter.

2002 • 189 citations

Pet study of [¹¹C] β‐CIT binding to monoamine transporters in the monkey and human brain

1994 • 184 citations

Imaging serotonin and dopamine transporters with 123I-beta-CIT SPECT: binding kinetics and effects of normal aging.

2000 • 181 citations

High affinity [3H]paroxetine binding to serotonin uptake sites in human brain tissue

1989 • 166 citations

2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand

2000 • 159 citations

Changes in Human In vivo Serotonin and Dopamine Transporter Availabilities during Chronic Antidepressant Administration

2002 • 158 citations

Human Research on MDMA (3,4-Methylene- dioxymethamphetamine) Neurotoxicity: Cognitive and Behavioural Indices of Change

2000 • 157 citations

Serotonin ClearanceIn VivoIs Altered to a Greater Extent by Antidepressant-Induced Downregulation of the Serotonin Transporter than by Acute Blockade of this Transporter

2002 • 148 citations

Serotonergic function after (±)3,4-methylene-dioxymethamphetarnine (‘Ecstasy’) in humans

1998 • 146 citations

In vivo quantification of brain serotonin transporters in humans using [11C]McN 5652.

2000 • 142 citations

Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions.

2002 • 137 citations

?-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo

1995 • 131 citations

Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user

2000 • 120 citations

Visualizing Dopamine and Serotonin Transporters in the Human Brain with the Potent Cocaine Analogue [¹²⁵I]RTI‐55: In Vitro Binding and Autoradiographic Characterization

1994 • 115 citations

Lung as reservoir for antidepressants in pharmacokinetic drug interactions

1998 • 95 citations

Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies.

1996 • 94 citations

[^123/125I]RTI‐55, an in vivo label for the serotonin transporter

1992 • 75 citations

Specific memory deficits in ecstasy users? The results of a meta‐analysis

2003 • 68 citations

In vivo visualization of serotonin transporters in the human brain during fluoxetine treatment

1999 • 57 citations

Whole-body biodistribution, radiation absorbed dose and brain SPECT imaging with iodine-123-beta-CIT in healthy human subjects.

1994 • 51 citations

Occupancy of the serotonin transporter by fluoxetine, paroxetine, and sertraline: In vivo studies with [¹²⁵i]rti‐55

1994 • 48 citations

[125I]β-CIT-FE and [125I]β-CIT-FP are superior to [125I]β-CIT for dopamine transporter visualization: Autoradiographic evaluation in the human brain

1997 • 42 citations

Validity of [¹²³I]β‐CIT SPECT in detecting MDMA‐induced serotonergic neurotoxicity

2002 • 33 citations

Validity of in vivo [I]?-CIT SPECT in detecting MDMA-induced neurotoxicity in rats

2003 • 16 citations