Validity of [123I]β‐CIT SPECT in detecting MDMA‐induced serotonergic neurotoxicity

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity

1988 • 548 citations

Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.

1987 • 526 citations

3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.

1987 • 455 citations

Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.

1987 • 451 citations

SPECT imaging of dopamine and serotonin transporters with [¹²³I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates

1993 • 357 citations

The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain

1986 • 354 citations

Altered Serotonin Innervation Patterns in the Forebrain of Monkeys Treated with (±)3,4-Methylenedioxymethamphetamine Seven Years Previously: Factors Influencing Abnormal Recovery

1999 • 340 citations

Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users

1999 • 286 citations

Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")

1995 • 268 citations

Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration

1988 • 255 citations

Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons

2001 • 253 citations

Autoradiography of antidepressant binding sites in the human brain: localization using [3h]imipramine and [3h]paroxetine

1988 • 219 citations

High‐affinity binding of [¹²⁵I]RTI‐55 to dopamine and serotonin transporters in rat brain

1992 • 211 citations

Methylenedioxymethamphetamine: A potentially neurotoxic amphetamine analogue

1986 • 206 citations

Cortical Serotonin Transporter Density and Verbal Memory in Individuals Who Stopped Using 3,4-Methylenedioxymethamphetamine (MDMA or "Ecstasy")

2001 • 196 citations

Pet study of [¹¹C] β‐CIT binding to monoamine transporters in the monkey and human brain

1994 • 184 citations

Regional and subcellular localization in human brain of [3H]paroxetine binding, a marker of serotonin uptake sites

1988 • 171 citations

High affinity [3H]paroxetine binding to serotonin uptake sites in human brain tissue

1989 • 166 citations

In vivo detection of short- and long-term MDMA neurotoxicity?a positron emission tomography study in the living baboon brain

1998 • 143 citations

Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions.

2002 • 137 citations

Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA)

1988 • 110 citations

Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations.

1996 • 109 citations

[123I]FP-CIT binds to the dopamine transporter as assessed by biodistribution studies in rats and SPECT studies in MPTP-lesioned monkeys

1997 • 106 citations

Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies.

1996 • 94 citations

[^123/125I]RTI‐55, an in vivo label for the serotonin transporter

1992 • 75 citations

Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis.

1990 • 72 citations

Functional Consequences of Repeated (±)3,4-Methylenedioxymethamphetamine (MDMA) Treatment in Rhesus Monkeys

2001 • 64 citations

Comparison of [3H]Paroxetine and [3H]Cyanoimipramine for Quantitative Measurement of Serotonin Transporter Sites in Human Brain

1996 • 58 citations

Occupancy of the serotonin transporter by fluoxetine, paroxetine, and sertraline: In vivo studies with [¹²⁵i]rti‐55

1994 • 48 citations

Serotonin, the Cerebellum and Ataxia (1993)

1993 • 36 citations

In vitro and in vivo characterization of newly developed iodinated 1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}piperazine derivatives in rats: Limited value as dopamine transporter SPECT ligands

1996 • 17 citations

Enhancement of [123I]?-CIT binding in the striatum with clomipramine: Is there a serotonin-dopamine interaction?

1997 • 17 citations

Comparative in vivo study of iodine-123-labeled ?-cit and nor-?-cit binding to serotonin transporters in rat brain

1999 • 12 citations

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