The Genes Encoding Anti-NP Antibodies in Inbred Strains of Mice

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region

1981 • 677 citations

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

1981 • 509 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

The Three-Dimensional Structure of a Phosphorylcholine-Binding Mouse Immunoglobulin Fab and the Nature of the Antigen Binding Site

1974 • 465 citations

Antibody diversity: Somatic hypermutation of rearranged VH genes

1981 • 334 citations

Analysis of the repertoire of anti‐NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response

1978 • 316 citations

Genetics, Expression, and Function of Idiotypes

1983 • 264 citations

Contemporary topics in molecular immunology

1974 • 158 citations

The genetic basis of antibody production: A single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse

1983 • 151 citations

Molecular basis of a mouse strain-specific anti-hapten response

1983 • 150 citations

Somatic variants of murine immunoglobulin λ light chains

1982 • 136 citations

Organization of four mouse lambda light chain immunoglobulin genes.

1981 • 127 citations

Chromosomal location of structural genes encoding murine immunoglobulin lambda light chains. Genetics of murine lambda light chains.

1981 • 121 citations

Multiple differences between the nucleic acid sequences of the IgG2aa and IgG2ab alleles of the mouse.

1981 • 118 citations

Anti-oxazolone hybridomas and the structure of the oxazolone idiotype.

1983 • 114 citations

Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity.

1981 • 109 citations

Recombination between antibody heavy chain variable-region genes: evidence for gene conversion.

1983 • 104 citations

Immunoglobulin V region variants in hybridoma cells. II. Recombination between V genes.

1982 • 86 citations

Secretion of a λ2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region

1983 • 80 citations

Dual expression of λ genes in the MOPC-315 plasmacytoma

1981 • 78 citations

Physical linkage of the constant region genes for immunoglobulins lambda I and lambda III.

1981 • 66 citations

Somatic Mutation in Genes for the Variable Portion of the Immunoglobulin Heavy Chain

1982 • 60 citations

Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions.

1983 • 59 citations

T and B cells that recognize the same antigen do not transcribe similar heavy chain variable region gene segments.

1983 • 54 citations

Immunoglobulin Structures at High Resolution

1975 • 40 citations

Two monoclonal antibodies against different antigens using the same VH germ-line gene

1983 • 29 citations

Immunoglobulin diversity: analysis of the germ-line V_Hgene repertoire of the murine anti-GAT response

1983 • 24 citations

Cross‐reactivity of the NP^a and NP^b idiotypic responses of BALB/c and C57BL/6 mice to (4‐hydroxy‐3‐nitrophenyl)acetyl (NP)

1982 • 18 citations

Annual Review of Immunology.

1983 • 14 citations