Surface-bound chemokines capture and prime T cells for synapse formation

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

2004 • 1,657 citations

Two-Photon Imaging of Lymphocyte Motility and Antigen Response in Intact Lymph Node

2002 • 1,177 citations

Chemokines and Cell Migration in Secondary Lymphoid Organs

1999 • 1,046 citations

Chemokines and the Arrest of Lymphocytes Rolling Under Flow Conditions

1998 • 1,013 citations

Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell–dendritic cell interaction

2006 • 795 citations

Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

2003 • 756 citations

T Cell Receptor Signaling Precedes Immunological Synapse Formation

2002 • 695 citations

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in theplt/pltmouse

2000 • 580 citations

Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

2005 • 561 citations

Imaging the Single Cell Dynamics of CD4+ T Cell Activation by Dendritic Cells in Lymph Nodes

2004 • 537 citations

Chemokines Trigger Immediate β2 Integrin Affinity and Mobility Changes

2000 • 517 citations

Role of Rho in Chemoattractant-Activated Leukocyte Adhesion Through Integrins

1996 • 494 citations

Epstein-Barr Virus–induced Molecule 1 Ligand Chemokine Is Expressed by Dendritic Cells in Lymphoid Tissues and Strongly Attracts Naive T Cells and Activated B Cells

1998 • 479 citations

Polarity of T Cell Shape, Motility, and Sensitivity to Antigen

1996 • 438 citations

Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines

2005 • 405 citations

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes

1997 • 386 citations

Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells

1999 • 367 citations

Differential Clustering of CD4 and CD3ζ During T Cell Recognition

2000 • 364 citations

T cell costimulation by chemokine receptors

2005 • 336 citations

Costimulation and endogenous MHC ligands contribute to T cell recognition

2001 • 302 citations

Neutrophil attractant/activation protein‐1 (interleukin‐8) induces in vitro neutrophil migration by haptotactic mechanism

1993 • 215 citations

A single class II myosin modulates T cell motility and stopping, but not synapse formation

2004 • 207 citations

Kinetics and Extent of T Cell Activation as Measured with the Calcium Signal

1997 • 194 citations

Identification of the Glycosaminoglycan Binding Site of the CC Chemokine, MCP-1

2004 • 194 citations

Cutting Edge: Hierarchy of Chemokine Receptor and TCR Signals Regulating T Cell Migration and Proliferation

2000 • 163 citations

Regulation of Myosin-IIA Assembly and Mts1 Binding by Heavy Chain Phosphorylation

2005 • 153 citations

Imaging Synapse Formation during Thymocyte Selection

2002 • 142 citations

The lymphoid chemokine CCL21 costimulates naïve T cell expansion and Th1 polarization of non-regulatory CD4+ T cells

2004 • 135 citations

Kinetics and expression patterns of chemokine receptors in human CD4⁺ T lymphocytes primed by myeloid or plasmacytoid dendritic cells

2003 • 117 citations

Mapping the sensitivity of T cells with an optical trap: Polarity and minimal number of receptors for Ca²⁺signaling

1999 • 109 citations

CC Chemokine Ligand 19 Secreted by Mature Dendritic Cells Increases Naive T Cell Scanning Behavior and Their Response to Rare Cognate Antigen

2005 • 94 citations

Stimulation of naïve T‐cell adhesion and immunological synapse formation by chemokine‐dependent and ‐independent mechanisms

2002 • 63 citations

Mechanisms of T cell motility and arrest: Deciphering the relationship between intra- and extracellular determinants

2005 • 34 citations