Th2 cell clonal anergy as a consequence of partial activation.

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1992 • 1,573 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.

1987 • 1,166 citations

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

1991 • 1,132 citations

Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

1993 • 911 citations

B70 antigen is a second ligand for CTLA-4 and CD28

1993 • 907 citations

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1991 • 660 citations

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

1993 • 595 citations

Separation of IL-4 Production from Th Cell Proliferation by an Altered T Cell Receptor Ligand

1991 • 565 citations

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.

1984 • 529 citations

Identification of an Alternative CTLA-4 Ligand Costimulatory for T Cell Activation

1993 • 517 citations

Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin.

1983 • 441 citations

Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands

1993 • 414 citations

Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells

1988 • 406 citations

Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness.

1987 • 391 citations

Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice

1993 • 369 citations

Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody.

1990 • 360 citations

Two better cell lines for making hybridomas expressing specific T cell receptors.

1989 • 300 citations

Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas.

1984 • 272 citations

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells.

1988 • 260 citations

Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation.

1991 • 255 citations

Role of interleukin 1 in the activation of T lymphocytes.

1988 • 231 citations

Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones.

1990 • 218 citations

T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells.

1988 • 212 citations

Split Anergy in a CD8 ⁺ T Cell: Receptor-dependent Cytolysis in the Absence of Interleukin-2 Production

1991 • 199 citations

Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells.

1990 • 144 citations

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas.

1992 • 131 citations

CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4.

1993 • 112 citations

Anti-CD3 antibody induces unresponsiveness to IL-2 in Th1 clones but not in Th2 clones.

1990 • 109 citations

Th1 and Th2 clones differ in their response to a tolerogenic signal.

1990 • 102 citations

Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice

1993 • 97 citations

Differential regulation of interleukin 4 and interleukin 5 gene expression: a comparison of T-cell gene induction by anti-CD3 antibody or by exogenous lymphokines.

1990 • 73 citations

In vivo induction of tolerance in murine CD4+ cell subsets.

1993 • 68 citations

Antagonism of superantigen-stimulated helper T-cell clones and hybridomas by altered peptide ligand.

1994 • 68 citations

Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones.

1991 • 64 citations

Antigen receptor-mediated anergy in resting T lymphocytes and T cell clones. Correlation with lymphokine secretion patterns.

1992 • 62 citations

Anergized T cell clones retain their cytolytic ability.

1993 • 44 citations

Hen egg-white lysozyme-specific T cells elicited in hen egg-white lysozyme-transgenic mice retain an imprint of self-tolerance.

1993 • 35 citations

Activation and growth of colony-stimulating factor-dependent cell lines is cell cycle stage dependent.

1987 • 28 citations

The use of the polymerase chain reaction to map CD4⁺ T cell epitopes

1991 • 23 citations