MONOCYTE-DERIVED DENDRITIC CELL PRECURSORS FACILITATE TOLERANCE TO HEART ALLOGRAFTS AFTER TOTAL LYMPHOID IRRADIATION1

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

‘Actively Acquired Tolerance’ of Foreign Cells

1953 • 3,103 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Improved technique of heart transplantation in rats

1969 • 1,338 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.

1993 • 502 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

1996 • 416 citations

Induction of specific tissue transplantation tolerance using fractionated total lymphoid irradiation in adult mice: long-term survival of allogeneic bone marrow and skin grafts.

1977 • 392 citations

HEART ALLOGRAFTS IN MURINE SYSTEMS

1992 • 299 citations

Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells

1994 • 298 citations

BONE MARROW-DERIVED DENDRITIC CELL PROGENITORS (NLDC 145+, MHC CLASS II+, B7-1dim, B7-2−) INDUCE ALLOANTIGEN-SPECIFIC HYPORESPONSIVENESS IN MURINE T LYMPHOCYTES1,2

1995 • 281 citations

Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival.

1995 • 202 citations

Donor CD8 cells prevent allogeneic marrow graft rejection in mice: potential implications for marrow transplantation in humans.

1993 • 195 citations

Granulocyte Colony-Stimulating Factor Reduces the Capacity of Blood Mononuclear Cells to Induce Graft-Versus-Host Disease: Impact on Blood Progenitor Cell Transplantation

1997 • 155 citations

ENHANCED TYPE 2 AND DIMINISHED TYPE 1 CYTOKINES IN NEONATAL TOLERANCE

1995 • 148 citations

FURTHER STUDIES OF VETO ACTIVITY IN RHESUS MONKEY BONE MARROW IN RELATION TO ALLOGRAFT TOLERANCE AND CHIMERISM

1994 • 130 citations

CTLA4-Ig PLUS BONE MARROW INDUCES LONG-TERM ALLOGRAFT SURVIVAL AND DONOR-SPECIFIC UNRESPONSIVENESS IN THE MURINE MODEL

1996 • 122 citations

Use of homozygous allogeneic bone marrow for induction of tolerance with antilymphocyte serum: dose and timing.

1971 • 86 citations

Generation of DC from mouse spleen cell cultures in response to GM-CSF: immunophenotypic and functional analyses.

1995 • 81 citations

Evidence for mouse Th1- and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation.

1989 • 68 citations

THE ROLE OF PURIFIED CD8+ T CELLS IN GRAFT-VERSUS-LEUKEMIA ACTIVITY AND ENGRAFTMENT AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION

1995 • 63 citations

The role of donor and recipient B7-1 (CD80) in allograft rejection.

1997 • 60 citations

THE DEVELOPMENT OF A POSTTRANSPLANT TLI TREATMENT STRATEGY THAT PROMOTES ORGAN ALLOGRAFT ACCEPTANCE WITHOUT CHRONIC IMMUNOSUPPRESSION>

1992 • 44 citations

??/??-T CELL RECEPTOR-DIRECTED THERAPY IN RAT ALLOGRAFT RECIPIENTS

1996 • 28 citations

MECHANISMS OF TOLERANCE TO RAT HEART ALLOGRAFTS USING POSTTRANSPLANT TLI

1996 • 24 citations

Deficits in T helper cells after total lymphoid irradiation (TLI): Reduced IL-2 secretion and normal IL-2 receptor expression in the mixed leukocyte reaction (MLR)

1990 • 12 citations

Generation of dendritic cells from mouse spleen cell cultures in response to GM-CSF: immunophenotypic and functional analyses

1995 • 11 citations