MECHANISMS OF TOLERANCE TO RAT HEART ALLOGRAFTS USING POSTTRANSPLANT TLI

A Cell Culture Model for T Lymphocyte Clonal Anergy

1990 • 1,894 citations

Improved technique of heart transplantation in rats

1969 • 1,338 citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1995 • 532 citations

Induction of specific tissue transplantation tolerance using fractionated total lymphoid irradiation in adult mice: long-term survival of allogeneic bone marrow and skin grafts.

1977 • 392 citations

HEART ALLOGRAFTS IN MURINE SYSTEMS

1992 • 299 citations

RANTES chemokine expression in cell-mediated transplant rejection of the kidney

1994 • 267 citations

Transplantation tolerance in adult rats using total lymphoid irradiation: permanent survival of skin, heart, and marrow allografts.

1978 • 201 citations

Acquired Immune Tolerance to Cadaveric Renal Allografts

1989 • 185 citations

Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and interferon-gamma in long-surviving mouse heart allografts after brief CD4-monoclonal antibody therapy.

1995 • 175 citations

ENHANCED TYPE 2 AND DIMINISHED TYPE 1 CYTOKINES IN NEONATAL TOLERANCE

1995 • 148 citations

INCREASED EXPRESSION OF IL-4 AND IL-10 AND DECREASED EXPRESSION OF IL-2 AND INTERFERON-γ IN LONG-SURVIVING MOUSE HEART ALLOGRAFTS AFTER BRIEF CD4-MONOCLONAL ANTIBODY THERAPY1,2

1995 • 142 citations

Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells.

1990 • 117 citations

Induction of specific unresponsiveness to heart allografts in mongrel dogs treated with total lymphoid irradiation and antithymocyte globulin.

1984 • 94 citations

GRAFT-INFILTRATING T HELPER CELLS, CD45RC PHENOTYPE, AND TH1/TH2-RELATED CYTOKINES IN DONOR-SPECIFIC TRANSFUSION–INDUCED TOLERANCE IN ADULT RATS

1995 • 91 citations

Total lymphoid irradiation in kidney and liver transplantation in the baboon: prolonged graft survival and alterations in T cell subsets with low cumulative dose regimens.

1984 • 75 citations

Evidence for mouse Th1- and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation.

1989 • 68 citations

Cellular basis of allograft rejection in vivo. V. Examination of the mechanisms responsible for the differing efficacy of monoclonal antibody to CD4+ T cell subsets in low- and high-responder rat strains.

1989 • 54 citations

THE DEVELOPMENT OF A POSTTRANSPLANT TLI TREATMENT STRATEGY THAT PROMOTES ORGAN ALLOGRAFT ACCEPTANCE WITHOUT CHRONIC IMMUNOSUPPRESSION>

1992 • 44 citations

SURVIVAL OF PRIMATES FOLLOWING ORTHOTOPIC CARDIAC TRANSPLANTATION TREATED WITH TOTAL LYMPHOID IRRADIATION AND CHEMICAL IMMUNE SUPPRESSION

1981 • 44 citations

In vitro propagation and cloning of murine natural suppressor (NS) cells.

1984 • 38 citations

LYMPHOKINE PRODUCTION BY MLR-REACTIVE REACTION LYMPHOCYTES OBTAINED FROM NORMAL MICE AND MICE RENDERED TOLERANT OF CLASS II MHC ANTIGENS

1989 • 32 citations

INDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN RATS USING POSTTRANSPLANT TOTAL LYMPHOID IRRADIATION AND ANTI-T CELL ANTIBODIES1

1993 • 30 citations

ALLOANTIGEN PRIMING AFTER TOTAL LYMPHOID IRRADIATION ALTERS ALLOIMMUNE CYTOKINE RESPONSES

1995 • 26 citations

ASSOCIATION OF DOWN-REGULATION OF CYTOKINE ACTIVITY WITH RAT HIND LIMB ALLOGRAFT SURVIVAL

1995 • 24 citations

Altered IFN-gamma and IL-4 pattern lymphokine secretion in mice partially depleted of CD4 T cells by anti-CD4 monoclonal antibody.

1992 • 23 citations

Antigen presenting ability of thymic macrophages and epithelial cells: Evidence for defects in the antigen processing function of thymic epithelial cells

1991 • 20 citations

Blocking of mixed lymphocyte reaction by spleen cells from total lymphoid-irradiated mice involves interruption of the IL-2 pathway.

1992 • 13 citations

Thymic irradiation inhibits the rapid recovery of TH1 but not TH2-Like functions of CD4+ T cells after total lymphoid irradiation

1991 • 11 citations

B cell infiltration of the thymic medulla in new zealand black, new zealand white, and (new zealand black × new zealand white)f₁ mice

1990 • 9 citations