Stereotyped and specific gene expression programs in human innate immune responses to bacteria

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1997 • 5,522 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes

2000 • 4,803 citations

Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation

1999 • 2,990 citations

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors

2000 • 2,076 citations

The Transcriptional Program of Sporulation in Budding Yeast

1998 • 1,876 citations

Innate Immunity

2000 • 1,715 citations

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

1999 • 1,714 citations

High-fidelity mRNA amplification for gene profiling

2000 • 693 citations

Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes

1999 • 450 citations

Phosphorylation and Activation of a cAMP-specific Phosphodiesterase by the cAMP-dependent Protein Kinase

1996 • 406 citations

Recognition of a bacterial adhesin by an integrin: Macrophage CR3 (αMβ2, ) binds filamentous hemagglutinin of Bordetella pertussis

1990 • 395 citations

Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence.

1989 • 350 citations

Impaired antigen presentation by human monocytes during endotoxin tolerance

2000 • 277 citations

T Cell Activation and the Cytoskeleton

2000 • 264 citations

Phase variation in Bordetella pertussis by frameshift mutation in a gene for a novel two-component system

1989 • 241 citations

In vitro activation of a human macrophage-like cell line

1979 • 205 citations

Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis

2000 • 197 citations

COMPARISON OF CYTOKINE PRODUCTION IN CULTURES OF WHOLE HUMAN BLOOD AND PURIFIED MONONUCLEAR CELLS

1999 • 160 citations

Innate immunity: Lipoproteins take their Toll on the host

1999 • 141 citations

Bordetella pertussis Infection: Pathogenesis, Diagnosis, Management, and the Role of Protective Immunity

2000 • 131 citations

CpG DNA Induces Maturation of Dendritic Cells with Distinct Effects on Nascent and Recycling MHC-II Antigen-Processing Mechanisms

2000 • 129 citations

Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death

2001 • 124 citations

Salmonella typhiFlagella Are Potent Inducers of Proinflammatory Cytokine Secretion by Human Monocytes

1999 • 122 citations

Adenosine - cyclic AMP pathways and cytokine expression.

1999 • 120 citations

cAMP Up-Regulates Cell Surface Expression of Lymphocyte CXCR4: Implications for Chemotaxis and HIV-1 Infection

1999 • 93 citations

Cyclooxygenase-2 Expression in Lipopolysaccharide-Stimulated Human Monocytes Is Modulated by Cyclic AMP, Prostaglandin E2, and Nonsteroidal Anti-inflammatory Drugs

2000 • 86 citations

Selective Inhibition of IgG-Mediated Phagocytosis in Gelsolin-Deficient Murine Neutrophils

2000 • 79 citations

Impaired antigen presentation by human monocytes during endotoxin tolerance

2000 • 78 citations

CpG Oligodeoxynucleotides Down-Regulate Macrophage Class II MHC Antigen Processing

1999 • 73 citations

Comparing functional genomic datasets: lessons from DNA microarray analyses of host–pathogen interactions

2001 • 65 citations

Targeted mutations that ablate either the adenylate cyclase or hemolysin function of the bifunctional cyaA toxin of Bordetella pertussis abolish virulence.

1992 • 60 citations

Whole blood model of meningococcal bacteraemia—a method for exploring host-bacterial interactions

1995 • 40 citations

How Do You See CG?

2000 • 39 citations

Bordetella pertussisInfection of Human Monocytes Inhibits Antigen‐Dependent CD4 T Cell Proliferation

1997 • 38 citations

cAMP attenuates interleukin-1-stimulated macrophage colony-stimulating factor (M-CSF) expression

2000 • 19 citations

IP-10 mRNA EXPRESSION IN CULTURED KERATINOCYTES IS SUPPRESSED BY INHIBITION OF PROTEIN KINASE-C AND TYROSINE KINASE AND ELEVATION OF cAMP

1999 • 14 citations