Significance of the enzyme complex that synthesizes UMP in ehrlich ascites cells

Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymes

1973 • 205 citations

The Biochemical Activity of 6-Azauridine: Interference with Pyrimidine Metabolism in Transplantable Mouse Tumors

1959 • 136 citations

Studies on a pyrimidine phosphoribosyltransferase from murine leukemia P1534J. Partial purification, substrate specificity, and evidence for its existence as a bifunctional complex with orotidine 5-phosphate decarboxylase.

1975 • 104 citations

Regulation of pyrimidine and arginine biosynthesis in mammals

1971 • 92 citations

Purification and Properties of Orotidine-5′-Phosphate Pyrophosphorylase and Orotidine-5′-Phosphate Decarboxylase from Bakers' Yeast

1971 • 91 citations

Purification and Kinetic Properties of Brain Orotidine 5′-Phosphate Decarboxylase

1968 • 87 citations

3-Ribosylpurines

1964 • 87 citations

Coordinate overproduction of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in hamster cells resistant to pyrazofurin and 6-azauridine.

1979 • 65 citations

Interconversion of different molecular weight forms of human erythrocyte orotidylate decarboxylase.

1975 • 59 citations

Purification, size, and properties of the complex of orotate phosphoribosyltransferase: orotidylate decarboxylase from mouse Ehrlich ascites carcinoma.

1976 • 56 citations

Inhibitors of orotate phosphoribosyl-transferase and orotidine-5'-phosphate decarboxylase from mouse ehrlich ascites cells: a procedure for analyzing the inhibition of a multi-enzyme complex

1977 • 54 citations

Kinetic and conformational studies of the orotate phosphoribosyltransferase:orotidine-5'-phosphate decarboxylase enzyme complex from mouse Ehrlich ascites cells

1977 • 52 citations

Pyrimidine pathway variants of cultured mouse lymphoma cells with altered levels of both orotate phosphoribosyltransferase and orotidylate decarboxylase.

1979 • 46 citations

Baker's yeast UMP:pyrophosphate phosphoribosyltransferase. Purification, enzymatic and kinetic properties.

1979 • 45 citations

Interconversion of different molecular weight forms of the orotate phosphoribosyltransferase.orotidine-5'-phosphate decarboxylase enzyme complex from mouse Ehrlich ascites cells.

1979 • 37 citations

Alteration of quaternary structural behaviour of an hepatic orotate phosphoribosyltransferase-orotidine-5′-phosphate decarboxylase complex in rats following allopurinol therapy

1972 • 37 citations

Subunit structure of the orotate phosphoribosyltransferase-orotidylate decarboxylase complex from human erythrocytes

1977 • 34 citations

Effect of 6-azauridine on de novo pyrimidine biosynthesis in cultured Ehrlich ascites cells. Orotate inhibition of dihydroorotase and dihydroorotate dehydrogenase.

1979 • 33 citations

Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.

1977 • 28 citations

Pyrimidine metabolism in hereditary erythrocyte pyrimidine 5′ nucleotidase deficiency

1978 • 22 citations

The rapid separation of orotate, orotidylate, and uridylate by thin-layer chromatography

1977 • 14 citations

Pyrimidine Metabolism in Erythrocytes of the Newborn

1979 • 9 citations

Mammalian synthesis of UMP from orotate: The regulation of and conformers of Complex U

1978 • 8 citations

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