Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease
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References (69)
“Mini-mental state”
1975 • 82,784 citations
Clinical diagnosis of Alzheimer's disease
1984 • 27,279 citations
Normative data on a battery of neuropsychological tests in the Han Chinese population
2010 • 20,181 citations
Special Care Units and Traditional Care in Dementia: Relationship with Behavior, Cognition, Functional Status and Quality of Life - A Review
2013 • 20,010 citations
Older Adults' Reasons for Using Technology while Aging in Place
2015 • 19,091 citations
Sensitivity and False Alarm Rate of a Fall Sensor in Long-Term Fall Detection in the Elderly
2014 • 18,386 citations
Neuropathological stageing of Alzheimer-related changes
1991 • 14,533 citations
Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families
1993 • 8,888 citations
The Clinical Dementia Rating (CDR)
1993 • 8,861 citations
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
1993 • 4,145 citations
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
1992 • 2,520 citations
Diagnosis of Alzheimer's Disease
1985 • 2,482 citations
Alzheimer's Disease: Cell-Specific Pathology Isolates the Hippocampal Formation
1984 • 2,199 citations
Observations on the brains of demented old people
1970 • 2,066 citations
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
1994 • 1,813 citations
The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease
1991 • 1,344 citations
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.
1993 • 1,329 citations
Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
1993 • 1,092 citations
Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease
1997 • 1,067 citations
MR‐based hippocampal volumetry in the diagnosis of Alzheimer's disease
1992 • 848 citations
Some morphometric aspects of the brain in senile dementia of the alzheimer type
1981 • 803 citations
Apolipoprotein E Status as a Predictor of the Development of Alzheimer's Disease in Memory-Impaired Individuals
1995 • 747 citations
Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging
1992 • 677 citations
Apolipoprotein E in animal models of CNS injury and in alzheimer's disease
1994 • 651 citations
Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease.
1995 • 596 citations
Anterior temporal lobes and hippocampal formations: normative volumetric measurements from MR images in young adults.
1989 • 592 citations
Regional pattern of degeneration in Alzheimer's disease: neuronal loss and histopathological grading
1981 • 567 citations
ApoE-4 and Age at Onset of Alzheimer's Disease
1997 • 467 citations
Temporal lobe seizures: lateralization with MR volume measurements of the hippocampal formation.
1990 • 431 citations
Hypothesis: Microtubule Instability and Paired Helical Filament Formation in the Alzheimer Disease Brain Are Related to Apolipoprotein E Genotype
1994 • 427 citations
Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease
1997 • 422 citations
Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer's disease
1991 • 421 citations
Volume loss of the hippocampus and temporal lobe in healthy elderly persons destined to develop dementia
1997 • 403 citations
The apolipoprotein ε4 allele in patients with Alzheimer's disease
1993 • 401 citations
Clinical and pathological correlates of apolipoprotein E ε4 in Alzheimer's disease
1996 • 384 citations
Temporal Lobe Regions on Magnetic Resonance Imaging Identify Patients With Early Alzheimer's Disease
1993 • 376 citations
The human hippocampus: An atlas of applied anatomy
1988 • 339 citations
Memory function in very early Alzheimer's disease
1994 • 335 citations
The radiologic prediction of Alzheimer disease: the atrophic hippocampal formation.
1993 • 314 citations
Amygdalohippocampal MR volume measurements in the early stages of Alzheimer disease.
1994 • 302 citations
Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer's disease: Correlation with memory functions
1995 • 280 citations
Apolipoprotein E allele ∈4, dementia, and cognitive decline in a population sample
1995 • 269 citations
Volumetric MRI analysis of the amygdala and the hippocampus in subjects with age‐associated memory impairment
1994 • 266 citations
Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease
1996 • 255 citations
Memory function in normal aging
1992 • 254 citations
Apolipoprotein E: risk factor for Alzheimer disease.
1994 • 253 citations
Apolipoprotein E genotyping in Alzheimer's disease
1996 • 235 citations
MRI‐Based Hippocampal Volume Measurements in Epilepsy
1994 • 224 citations
The limbic system in Alzheimer's disease. A neuropathologic investigation.
1976 • 204 citations
Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: population based study
1994 • 201 citations
MR imaging-based volume measurements of the hippocampal formation and anterior temporal lobe: validation studies.
1990 • 197 citations
Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons.
1997 • 174 citations
Quantitative Changes in Mesial Temporal Volume, Regional Cerebral Blood Flow, and Cognition in Alzheimer's Disease
1992 • 173 citations
Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes
1995 • 166 citations
Apolipoprotein e4 allele and cognitive decline in elderly men
1994 • 164 citations
Apolipoprotein E ϵ4 allele and hippocampal volume in twins with normal cognition
1997 • 149 citations
Procedures for setting normal values
1995 • 147 citations
Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease
1996 • 144 citations
Hippocampal atrophy in early Alzheimer's Disease: Anatomic specificity and validation
1993 • 133 citations
SPECT and MRI analysis in Alzheimer's disease: relation to apolipoprotein E epsilon 4 allele.
1996 • 125 citations
Do Older Women Use Estrogen Replacement? Data from the Duke Established Populations for Epidemiologic Studies of the Elderly (EPESE)
1996 • 118 citations
Apolipoprotein E ϵ4 and Incidence of Alzheimer Disease in a Community Population of Older Persons
1997 • 94 citations
A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease
1997 • 81 citations
Mayo Clinic Alzheimer’s Disease Patient Registry
1990 • 75 citations
Alzheimer's disease is a laminar, regional, and neural system specific disease, not a global brain disease
1994 • 75 citations
Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E.
1996 • 71 citations
Alzheimer Amyloid-β Peptide Forms Denaturant-Resistant Complex with Type ε3 but Not Type ε4 Isoform of Native Apolipoprotein E
1996 • 45 citations
Solvation Effects on the Conformational Behaviour of Gellan and Calcium Ion Binding to Gellan Double Helices
1996 • 39 citations
GERIATRIC BIOSCIENCE: Apolipoprotein E Genotype: Utility in Clinical Practice in Alzheimer's Disease
1996 • 9 citations