Structural stabilization of botulinum neurotoxins by tyrosine phosphorylation

Examination of the secondary structure of proteins by deconvolved FTIR spectra

1986 • 2,865 citations

Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins

1986 • 2,761 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

Determination of protein secondary structure by Fourier transform infrared spectroscopy: A critical assessment

1993 • 1,489 citations

Mechanism of action of tetanus and botulinum neurotoxins

1994 • 532 citations

Synaptic Vesicles and Exocytosis

1994 • 371 citations

THERAPY—BOTULINUM TOXIN

2002 • 352 citations

The Effects of Phosphorylation on the Structure and Function of Proteins

1993 • 266 citations

Fourier Transform Infrared Techniques for Probing Membrane Protein Structure

1988 • 248 citations

Bacterial protein toxins penetrate cells via a four‐step mechanism

1994 • 224 citations

Calorimetrically Determined Dynamics of Complex Unfolding Transitions in Proteins

1990 • 212 citations

Separation, purification, partial characterization and comparison of the heavy and light chains of botulinum neurotoxin types A, B, and E.

1985 • 161 citations

Structure, stability, and receptor interaction of cholera toxin as studied by Fourier-transform infrared spectroscopy

1990 • 118 citations

FTIR spectroscopic studies of the conformation and amide hydrogen exchange of a peptide model of the hydrophobic transmembrane .alpha.-helixes of membrane proteins

1992 • 111 citations

Molecular aspects of tetanus and botulinum neurotoxin poisoning

1995 • 105 citations

Fourier Transform Infrared and Hydrogen/Deuterium Exchange Reveal an Exchange-resistant Core of α -Helical Peptide Hydrogens in the Nicotinic Acetylcholine Receptor

1995 • 84 citations

Surface-Core Relationships in Human Low Density Lipoprotein as Studied by Infrared Spectroscopy

1995 • 77 citations

Infrared spectroscopic characterization of the structural changes connected with the E1→E2 transition in the Ca2+-ATPase of sarcoplasmic reticulum.

1987 • 73 citations

Significance of 12 S Toxin of Clostridium botulinum Type E

1969 • 72 citations

Engineering enzymes for stability

1996 • 62 citations

Tyrosine Phosphorylation Modulates the Activity of Clostridial Neurotoxins

1996 • 55 citations

[9] Fourier resolution enhancement of infrared spectral data

1992 • 51 citations

Agonist-independent activation of acetylcholine receptor channels by protein kinase A phosphorylation.

1991 • 41 citations

Protein stability and interaction of the nicotinic acetylcholine receptor with cholinergic ligands studied by Fourier-transform infrared spectroscopy

1992 • 40 citations

Structural basis for the extreme thermostability of D-glyceraldehyde-3-phosphate dehydrogenase from Thermotoga maritima: analysis based on homology modelling

1995 • 32 citations

Protein structural effects of agonist binding to the nicotinic acetylcholine receptor

1992 • 29 citations

Removal of spectral noise in the quantitation of protein structure through infrared band decomposition

1997 • 27 citations

Structural analysis of botulinum neurotoxin types A and E in aqueous and nonpolar solvents by Fourier transform infrared, second derivative UV absorption, and circular dichroic spectroscopies

1990 • 20 citations

Thermal perturbation studies of membrane-bound acetylcholine receptor from Torpedo: Effects of cholinergic ligands and membrane perturbants

1987 • 15 citations