Organization of the Drosophila melanogaster hsp70 heat shock regulation unit.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

1982 • 1,038 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

A drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene

1984 • 534 citations

Multiple sequence motifs are involved in SV40 enhancer function.

1986 • 511 citations

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

1984 • 474 citations

Activating protein factor binds in vitro to upstream control sequences in heat shock gene chromatin

1984 • 329 citations

Sequences required for in vitro transcriptional activation of a Drosophila hsp 70 gene

1985 • 291 citations

Determinants of heat shock-induced chromosome puffing

1985 • 281 citations

Activation of heat-shock genes in eukaryotes

1985 • 263 citations

Heat shock regulatory elements function as an inducible enhancer in the xenopus hsp70 gene and when linked to a heterologous promoter

1986 • 239 citations

An SV40 “enhancer trap” incorporates exogenous enhancers or generates enhancers from its own sequences

1984 • 223 citations

Upstream elements necessary for optimal function of the hsp 70 promoter in transformed flies

1984 • 213 citations

Nucleotide sequence analysis of the Drosophila small heat shock gene cluster at locus 67B

1983 • 198 citations

Regulation of heat-shock genes: a DNA sequence upstream of Drosophila hsp70 genes is essential for their induction in monkey cells.

1982 • 171 citations

Isolation and functional analysis of a human 70,000-dalton heat shock protein gene segment.

1985 • 164 citations

Extensive regions of homology in front of the two hsp70 heat shock variant genes in Drosophila melanogaster

1981 • 161 citations

Separate regulatory elements for the heat-inducible and ovarian expression of the drosophila hsp26 gene

1985 • 138 citations

Activation of the Drosophila hsp27 promoter by heat shock and by ecdysone involves independent and remote regulatory sequences

1986 • 128 citations

Heat shock and ecdysterone activation of the Drosophila melanogaster hsp23 gene; a sequence element implied in developmental regulation.

1986 • 112 citations

Nucleotide sequences of heat shock activated genes in Drosophila melanogaster. I. Sequences in the regions of the 5′ and 3′ ends of the hsp 70 gene in the hybrid plasmid 56H8

1980 • 104 citations

Transcription of a Drosophila heat shock gene is heat-induced in Xenopus oocytes.

1982 • 102 citations

Binding of Drosophila heat-shock gene transcription factor to the hsp 70 promoter. Evidence for symmetric and dynamic interactions.

1986 • 93 citations

Two genes for the major heat-shock protein of Drosophila melanogaster arranged as an inverted repeat

1980 • 89 citations

Expression of a Drosophila heat-shock protein in Xenopus oocytes: conserved and divergent regulatory signals.

1982 • 85 citations

The Heat Shock Consensus Sequence Is Not Sufficient for hsp70 Gene Expression in Drosophila melanogaster

1985 • 73 citations

Sequence requirement for expression of the Drosophila melanogaster heat shock protein hsp22 gene during heat shock and normal development.

1986 • 55 citations

Inducible transcription and puffing in Drosophila melanogaster transformed with hsp70-phage lambda hybrid heat shock genes.

1984 • 51 citations

Several hundred base pairs upstream of Drosophila hsp23 and 26 genes are required for their heat induction in transformed flies.

1986 • 50 citations

Sequences involved in temperature and ecdysterone-induced transcription are located in separate regions of a Drosophila melanogaster heat shock gene.

1986 • 48 citations

Expression of heat shock-β-galactosidase hybrid genes in cultured Drosophila cells

1984 • 40 citations

A viable simian virus 40 variant that carries a newly generated sequence reiteration in place of the normal duplicated enhancer element.

1984 • 38 citations

The heat shock consensus sequence is not sufficient for hsp70 gene expression in Drosophila melanogaster.

1985 • 36 citations

Ecdysterone selectively stimulates the expression of a 23000-Da heat-shock protein-β-galactosidase hybrid gene in cultured Drosophila cells

1985 • 35 citations

Activation of gene expression is adversely affected at high multiplicities of linked simian virus 40 enhancer.

1986 • 24 citations