Smad4 and transforming growth factor beta1 expression in patients with squamous cell carcinoma of the esophagus.

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways

1996 • 899 citations

DPC4 gene in various tumor types.

1996 • 680 citations

Enhanced expression of transforming growth factor β isoforms in pancreatic cancer correlates with decreased survival

1993 • 518 citations

Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis

1999 • 430 citations

Tumor suppressor activity of the TGF-β pathway in human cancers

1996 • 412 citations

Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer.

1992 • 346 citations

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

1997 • 317 citations

Functions of mammalian Smad genes as revealed by targeted gene disruption in mice

2000 • 174 citations

Role of Transforming Growth Factor-β1 in Invasion and Metastasis in Gastric Carcinoma

1999 • 157 citations

The expression of transforming growth factor-?1 is significantly correlated with the expression of vascular endothelial growth factor and poor prognosis of patients with advanced gastric carcinoma

1999 • 154 citations

A Gene for Familial Juvenile Polyposis Maps to Chromosome 18q21.1

1998 • 120 citations

Expression of Smad proteins in human colorectal cancer

1999 • 113 citations

ALLELOTYPE OF ADENOMA AND DIFFERENTIATED ADENOCARCINOMA OF THE STOMACH

1996 • 103 citations

Independent regulation of growth and SMAD-mediated transcription by transforming growth factor beta in human melanoma cells.

1999 • 74 citations

Immunocytochemically Detectable TGF-β Associated with Malignancy in Thyroid Epithelial Neoplasia

1990 • 63 citations

Preserved Smad4 expression in the transforming growth factor beta signaling pathway is a favorable prognostic factor in patients with advanced gastric cancer.

2001 • 53 citations

Smad4 (DPC4) - a potent tumour suppressor?

1998 • 42 citations

A novel SMAD4 gene mutation in seminoma germ cell tumors.

2000 • 41 citations

Overexpression of Transforming Growth Factor-β1 in Scirrhous Carcinoma of the Stomach Correlates with Decreased Survival

1998 • 34 citations

Gastro-intestinal tumorigenesis in Smad4 mutant mice

2000 • 33 citations

Mutation analysis of transforming growth factor beta type II receptor, Smad2, Smad3 and Smad4 in esophageal squamous cell carcinoma.

2000 • 33 citations