Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells

THIOREDOXIN

1985 • 1,885 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

REDOX REGULATION OF CELLULAR ACTIVATION

1997 • 1,121 citations

Regulation of the Erythropoietin Gene: Evidence That the Oxygen Sensor Is a Heme Protein

1988 • 1,042 citations

[21] Thioredoxin and thioredoxin reductase

1995 • 932 citations

A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration

1980 • 915 citations

A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration

1980 • 589 citations

Identification of Defensin-1, Defensin-2, and CAP37/Azurocidin as T-cell Chemoattractant Proteins Released from Interleukin-8-stimulated Neutrophils

1996 • 551 citations

Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway.

1992 • 463 citations

G protein-coupled signal transduction pathways for interleukin-8

1993 • 385 citations

[29] Glutaredoxin

1995 • 284 citations

Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2.

1990 • 283 citations

Intravascular IL-8. Inhibitor of polymorphonuclear leukocyte accumulation at sites of acute inflammation.

1991 • 262 citations

Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide

1994 • 252 citations

Elevation of plasma thioredoxin levels in HIV-infected individuals

1996 • 209 citations

Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity.

1996 • 203 citations

High level monocyte chemoattractant protein-1 expression in transgenic mice increases their susceptibility to intracellular pathogens.

1995 • 191 citations

Selective G Protein Coupling by C-C Chemokine Receptors

1996 • 191 citations

Long-term impaired neutrophil migration in mice overexpressing human interleukin-8.

1994 • 171 citations

Evidence for the role of an altered redox state in hyporesponsiveness of synovial T cells in rheumatoid arthritis.

1997 • 170 citations

Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation

1992 • 166 citations

Thioredoxin as a potent costimulus of cytokine expression.

1996 • 166 citations

Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione

1993 • 162 citations

Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells.

1996 • 161 citations

8 Color, 10-parameter flow cytometry to elucidate complex leukocyte heterogeneity

1997 • 160 citations

Chemotaxis in a lymphocyte cell line transfected with C-C chemokine receptor 2B: Evidence that directed migration is mediated by βγ dimers released by activation of G_αi-coupled receptors

1997 • 158 citations

Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism.

1995 • 147 citations

Monocyte function in intravenous drug abusers with lymphadenopathy syndrome and in patients with acquired immunodeficiency syndrome: selective impairment of chemotaxis.

1985 • 135 citations

Measurements of Plasma Glutaredoxin and Thioredoxin in Healthy Volunteers and During Open-Heart Surgery

1998 • 126 citations

Secretion of thioredoxin after in vitro activation of human B cells.

1992 • 116 citations

Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells

1995 • 115 citations

Adult T leukemia cells produce a lymphokine that augments interleukin 2 receptor expression.

1985 • 111 citations

Mismatch Binding Protein-Based Mutation Detection Systems

1995 • 111 citations

ADF, A Growth-Promoting Factor Derived from Adult T Cell Leukemia and Homologous to Thioredoxin: Involvement in Lymphocyte Immortalization by HTLV-I and EBV

1991 • 104 citations

Impairment of polymorphonuclear leucocyte function in patients with acquired immunodeficiency syndrome and with lymphadenopathy syndrome.

1986 • 99 citations

High rates of thioredoxin secretion correlate with growth arrest in hepatoma cells.

1995 • 89 citations

The reductive enzyme thioredoxin 1 acts as an oxidant when it is exported to the Escherichia coli periplasm

1998 • 85 citations

Thioredoxin Expression and Localization in Human Cell Lines: Detection of Full-Length and Truncated Species

1997 • 84 citations

Carrageenan‐induced acute inflammation in the mouse air pouch synovial model. Role of tumour necrosis factor

1997 • 79 citations

Thioredoxin increases the proliferation of human B-cell lines through a protein kinase C-dependent mechanism.

1994 • 77 citations

Localization of thioredoxin in the rat brain and functional implications

1995 • 74 citations

IL-1β primes IL-8-activated human neutrophils for elastase release, phospholipase D activity, and calcium flux

1996 • 65 citations

Astroglial expression of ATL-derived factor, a human thioredoxin homologue, in the gerbil brain after transient global ischemia

1993 • 64 citations

Human eosinophil cytotoxicity-enhancing factor. Eosinophil-stimulating and dithiol reductase activities of biosynthetic (recombinant) species with COOH-terminal deletions.

1993 • 62 citations

Purification, characterization, and complete amino acid sequence of a thioredoxin from a green alga, Chlamydomonas reinhardtii

1990 • 40 citations

Pairs of violet-light-excited fluorochromes for flow cytometric analysis

1998 • 40 citations

Identification of glutathione S-transferase isozymes and ?-glutamylcysteine synthetase as negative acute-phase proteins in rat liver

1998 • 36 citations

Thioredoxin from Activated Macrophages as a Trophic Factor for Central Cholinergic Neurons in Vitro

1993 • 36 citations

Detection of Membrane Associated Thioredoxin on Human Cell Lines

1997 • 33 citations

Identification of MIP-1α/LD78 as a Monocyte Chemoattractant Released by the HTLV-I-Transformed Cell Line MT4

1995 • 28 citations

Regulation of eosinophil migration by adult T cell leukemia-derived factor.

1993 • 26 citations

Single-cell analysis of macrophage chemotactic protein-1-regulated cytosolic Ca2+ increase in human adherent monocytes

1995 • 23 citations

Chemoattractant(s) in Culture Supernatants of HTLV-I-Infected T-Cell Lines

1991 • 8 citations