Role of transforming growth factor‐β and hepatocyte growth factor in late normal tissue effects of radiation

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1991 • 1,176 citations

Transforming growth factor-beta in disease: the dark side of tissue repair.

1992 • 1,126 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1990 • 1,002 citations

Accelerated Healing of Incisional Wounds in Rats Induced by Transforming Growth Factor-β

1987 • 938 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy.

1993 • 819 citations

Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis.

1991 • 794 citations

Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.

1991 • 698 citations

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system

1991 • 661 citations

Transforming Growth Factors β1 and α in Chronic Liver Disease

1991 • 655 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

Growth factors in wound healing. Single and synergistic effects on partial thickness porcine skin wounds.

1989 • 539 citations

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.

1991 • 521 citations

TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

1990 • 447 citations

Cloning of a Type I TGF-β Receptor and Its Effect on TGF-β Binding to the Type II Receptor

1993 • 401 citations

Inactivation of the Type II Receptor Reveals Two Receptor Pathways for the Diverse TGF-β Activities

1993 • 388 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions.

1992 • 327 citations

Transforming Growth Factor β as a Predictor of Liver and Lung Fibrosis after Autologous Bone Marrow Transplantation for Advanced Breast Cancer

1993 • 318 citations

Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells.

1993 • 290 citations

Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells.

1992 • 256 citations

Promoter Sequences of the Human Transforming Growth Factor-β1 Gene Responsive to Transforming Growth Factor-β1 Autoinduction

1989 • 254 citations

Hepatocyte growth factor may act as a pulmotrophic factor on lung regeneration after acute lung injury.

1993 • 253 citations

The met Proto-Oncogene Receptor and Lumen Formation

1992 • 246 citations

Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta 1 precursor.

1988 • 211 citations

Regulation of cell movement: the motogenic cytokines

1991 • 199 citations

Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-beta precede bleomycin-induced pulmonary fibrosis in mice.

1988 • 199 citations

The pro domain of pre-pro-transforming growth factor .beta.1 when independently expressed is a functional binding protein for the mature growth factor

1990 • 185 citations

Transforming growth factor-beta 1 expression in irradiated liver.

1990 • 178 citations

Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four Kringle domains with homology to hepatocyte growth factor

1991 • 161 citations

Hepatocyte growth factor-scatter factor (HGF-SF) and the C-met receptor

1993 • 146 citations

Transforming Growth Factor-β1 Expression in Irradiated Liver

1990 • 145 citations

Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: Cloning of its cDNA, purification and characterization of recombinant protein

1991 • 139 citations

Regulation of TGFβ gene expression in rat liver intoxicated with carbon tetrachloride

1990 • 137 citations

Roles of HGF as a pleiotropic factor in organ regeneration.

1993 • 131 citations

Transforming growth factor beta: a promotor of late connective tissue injury following radiotherapy?

1990 • 131 citations

Interactions of recombinant and platelet transforming growth factor-β1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor

1989 • 127 citations

Transforming growth factor beta 1 induces cachexia and systemic fibrosis without an antitumor effect in nude mice.

1991 • 121 citations

Exaggerated Radiation-Induced Fibrosis in Patients With Systemic Sclerosis

1991 • 115 citations

Modulation of insulin-like growth factor-II/mannose 6-phosphate receptors and transforming growth factor-beta 1 during liver regeneration.

1991 • 113 citations

Liver tumor promotion: Effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-?1 expression

1991 • 89 citations

Expression of Tumor Necrosis Factor-α and Transforming Growth Factor-β1 in Acute Liver Injury

1989 • 84 citations

Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development

1991 • 74 citations

Alpha 2-macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-beta 2 in rat hepatocytes.

1990 • 64 citations

Radiation Sensitivity of the Liver

1990 • 60 citations

Purification and Immunological Characterization of the Rat Liver Insulin-Like Growth Factor-II Receptor

1987 • 57 citations

Transforming growth factor-β1 and mannose 6-phosphate/insulin-like growth factor-II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat

1994 • 55 citations

TGF‐β and Wound Healing

2007 • 50 citations

Analysis of Local mRNA Expression for Extracellular Matrix Proteins and Growth Factors Using in situ Hybridization in Fibroproliferative Lung Disorders

1991 • 50 citations

Early increases in pulmonary mRNA encoding procollagens and transforming growth factor-beta in mice sensitive to cyclophosphamide-induced pulmonary fibrosis.

1989 • 41 citations

Collagen Synthesis and Degradation by Systemic Sclerosis Lung Fibroblasts

1991 • 24 citations

Are hepatocyte growth factor‐like protein and macrophage stimulating protein the same protein?

1993 • 22 citations

Isoforms of human HGF and their biological activities.

1993 • 17 citations

The protective effect of cyclosporine against cirrhotic alteration of the liver.

1991 • 13 citations