Transforming growth factor-β1 and mannose 6-phosphate/insulin-like growth factor-II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

1961 • 3,860 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.

1985 • 839 citations

Transforming Growth Factors β1 and α in Chronic Liver Disease

1991 • 655 citations

Distribution and modulation of the cellular receptor for transforming growth factor-beta.

1987 • 556 citations

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.

1988 • 548 citations

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.

1991 • 521 citations

The murine transforming growth factor-beta precursor.

1986 • 492 citations

Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation.

1988 • 483 citations

Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat.

1988 • 424 citations

In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis.

1989 • 420 citations

Localization and actions of transforming growth factor-βs in the embryonic nervous system

1991 • 360 citations

Cellular distribution of transforming growth factor-beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride-induced rat liver fibrosis.

1990 • 354 citations

Normal embryo fibroblasts release transforming growth factors in a latent form

1984 • 336 citations

Inositol 1,4,5-trisphosphate microinjection activates sea urchin eggs

1984 • 316 citations

Antibodies to the N-terminal portion of cartilage-inducing factor A and transforming growth factor beta. Immunohistochemical localization and association with differentiating cells.

1986 • 271 citations

Origin, pattern, and mechanism of bile duct proliferation following biliary obstruction in the rat

1990 • 227 citations

Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta 1 precursor.

1988 • 211 citations

Estimation of hydroxyproline by the AutoAnalyser

1964 • 201 citations

Transforming growth factor-beta 1, -beta 2, and -beta 3 secreted by a human glioblastoma cell line. Identification of small and different forms of large latent complexes.

1992 • 181 citations

Differential effects of interleukin‐1α, tumor necrosis factor α, and transforming growth factor β1 on cell proliferation and collagen formation by cultured fat‐storing cells

1989 • 178 citations

Regulation of TGFβ gene expression in rat liver intoxicated with carbon tetrachloride

1990 • 137 citations

Interactions of recombinant and platelet transforming growth factor-β1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor

1989 • 127 citations

Modulation of insulin-like growth factor-II/mannose 6-phosphate receptors and transforming growth factor-beta 1 during liver regeneration.

1991 • 113 citations

Modulation of hepatic lipocyte proteoglycan synthesis and proliferation by Kupffer cell-derived transforming growth factors type β1 and type α

1990 • 103 citations

Cloning and Sequence Analysis of Simian Transforming Growth Factor-β cDNA

1987 • 95 citations

Purification and Immunological Characterization of the Rat Liver Insulin-Like Growth Factor-II Receptor

1987 • 57 citations

The Multifunctional Nature of Peptide Growth Factors

1990 • 52 citations